PrECISE project deliverables
The page lists 28 deliverables related to the research project "PrECISE".
List of Deliverables
| title and desprition | type | last update |
|---|---|---|
Generate SWATH proteome profiles from sample punches prepared in D.6.2This deliverable converts the validation cohort tissue samples into quantitative protein profiles. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
1st Interim Progress ReportThe interim project progress report will address the main achievements and concrete key outcomes of the first project year (project summary, work performed and main results, risk assessment, list of scientific publications and dissemination activities). All work packages will summarize their work, challenges and outcomes in order to contribute to this report. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Network reconstruction algorithms for MS dataProvides novel algorithms for protein network reconstruction tailored to the MS data format of partner ETH and evaluated on the already existing prostatic cell line data of ETH. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Re-implement methodsAnalyses methods will be refactored and re-implemented within the framework. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
2nd Interim Progress ReportThe interim project progress report will address the main achievements and concrete key outcomes of the second project year (project summary, work performed and main results, risk assessment, list of scientific publications and dissemination activities). All work packages will summarize their work, challenges and outcomes in order to contribute to this report. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Generate amplicon sequencing profiles from sample punches prepared in D.6.2This deliverable converts the validation cohort tissue samples into quantitative genomic amplicon profiles. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Proteomic data sets in cancer cell linesIn this deliverable the data required to train the logical models will be provided. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Data input and input interfaceWe will input data and implement a framework for depositing future data into SmartBiobank. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Robust cross-cohort clinical patient classifierWe will provide molecular signatures and/or biomarkers of clinical groups based on the integration of all analyzed data types. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
A complete catalogue of targeted profilesThis report will provide normalized molecular profiles, including DNA and protein-expression profiles, of all biopsies studied in WP2. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Clonal classification of tumoursClassification of tumours according to dominant clonal content. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Targeted profiling of prospective cohortThis report will provide profiles of selected biopsies and will be used to inform sample and assay selection in WP6. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Integrate methods, including ACSN and WatsonWe will finalize dashboard implementation and interface with data access and depository, refactored methods, ACSN, and Watson. Integration of data and methods will be followed by extensive application testing. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Generate cell line drug sensitivity/resistance validation assaysThis deliverable will validate the drug predictions for prostatic cell lines inferred in WP5. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Catalogue of molecular alterations and dysregulated pathwaysWe will provide lists of molecular alterations and targeted pathways. The list will be segregated according to pathological stage (Gleason score), clonal structure and patient. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Identification of systematic alterations of networks for different prognosis and for different clonal compositionFound alterations enable the comparison with the genomic analysis of WP1 and provide predictions to be validated in WP6. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Final clone inferenceRefined clonality models and associated biomarkers. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Internal and external IT communication infrastructure and project websiteThe external IT communication infrastructure constitutes a guideline for communication of the PrECISE project to external target groups including conferences, marketing measures and communication channels. Furthermore this deliverable constitutes the launch of the internal PrECISE communication infrastructure including the establishment of mailing lists or a subversion server, and the PrECISE website. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Websites, patent fillings, videos etc. | 2020-03-25 |
Project quality planThe project quality plan (the project handbook) constitutes a set of project templates, explanations on the project management process, review process, quality checks, meeting organisation, which is communicated to all partners. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Interactome of molecular interactions in prostate cancerThis deliverable provides comprehensive information of all known and inferred interactions in prostate cancer. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Generic modelIn this deliverable, we will construct a generic logical model that will include altered signalling pathways identified by WP3 and WP4, complemented by pathways that are known to be frequently altered in cancer. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
First data-driven reconstruction of context-specific networkProteome networks based on MS and phospho-MS data from prostatic cells lines and from samples of the proCOC and MetaProC biopsies. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Computational pipeline to extract prior network information at the proteomic levelProvides a computational tool to extract and to mathematically aggregate prior information for later use in data-driven network reconstruction. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |
Targeted ultra-deep sequencing of cancer-gene lociThis report will provide targeted profiles of selected biopsies and will be used to improve clone inference in WP1, prognostic-biomarker inference in WP3, and tumour classification in WP4. Results will influence the construction of amplicon deliverables in D2.2 and D2.3. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Data Management PlanThe purpose of the DMP is to provide an analysis of the main elements of the data management policy that will be used by the applications with regard to all the datasets that will be generated by the project. The DMP is not a fixed document, but evolves during the lifespan of the project. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Final regulatory network inferenceRefined reversed engineered regulatory networks in PC tumours based on updated methodology for network integration and analyses of small datasets. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Ultra-deep sequencing of prognostic biomarkersThis report will provide targeted profiles of selected biopsies and will be used improve clone inference in WP1, prognostic-biomarker inference in WP3, tumour classification WP4, sample and assay selection in WP6. Results will influence the construction of amplicon deliverables in D2.3. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Documents, reports | 2020-03-25 |
Design and integrate pathway visualizationWe will provide visual profiles of data from patients, clones and cell lines using ACSN and networks created in WP3 and WP5. Programme: H2020-EU.3.1.1. - Topic(s): PHC-02-2015 |
Other | 2020-03-25 |