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ESCAPE-NET SIGNED

European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

ESCAPE-NET project word cloud

Explore the words cloud of the ESCAPE-NET project. It provides you a very rough idea of what is the project "ESCAPE-NET" about.

outcomes happens samples gt policies combining survival environmental lack genetic first created building dna minutes left heart networks rates translate cohorts arrest risk sufficiently treatment patient resuscitation 20 medical database rhythm differences sca inherited obtaining suddenly teams sudden hampered influencing causes countries lethal forces databases unexpectedly clinical association cardiac data population professional council patients mostly infrastructures occurrence acquired health scientific collaborating prevention individualized designing presently strategies efforts untreated deaths join

Project "ESCAPE-NET" data sheet

The following table provides information about the project.

Coordinator	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	http://www.escape-net.eu
Total cost	9˙992˙881 €
EC max contribution	9˙992˙881 € (100%)
Programme	1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
Code Call	H2020-SC1-2016-RTD
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2021-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	coordinator	2˙618˙678.00
2	REGION HOVEDSTADEN REGION HOVEDSTADEN Organization address address: KONGENS VAENGE 2 city: HILLEROD postcode: 3400 website: www.regionh.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (HILLEROD)	participant	1˙601˙250.00
3	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Organization address address: INGOLSTADTER LANDSTRASSE 1 city: NEUHERBERG postcode: 85764 website: www.helmholtz-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (NEUHERBERG)	participant	1˙146˙562.00
4	UNIVERSITE DE PARIS UNIVERSITE DE PARIS Organization address address: 85 BD SAINT GERMAIN city: PARIS postcode: 75006 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	678˙750.00
5	ISTITUTO AUXOLOGICO ITALIANO ISTITUTO AUXOLOGICO ITALIANO Organization address address: VIA L. ARIOSTO 13 city: MILANO postcode: 20145 website: www.auxologico.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	665˙625.00
6	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	640˙000.00
7	BIOCOMPUTING PLATFORMS LTD OY BIOCOMPUTING PLATFORMS LTD OY Organization address address: INNOPOLI 3 VAISALANTIE 6 city: ESPOO postcode: 2130 website: www.bcplatforms.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (ESPOO)	participant	349˙500.00
8	ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI Organization address address: VIA MARIO NEGRI 2 city: MILANO postcode: 20156 website: www.marionegri.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	347˙281.00
9	STICHTING VUMC STICHTING VUMC Organization address address: DE BOELELAAN 1117 city: AMSTERDAM postcode: 1081 HV website: www.vumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	345˙125.00
10	FUNDACIO INSTITUT MAR D INVESTIGACIONS MEDIQUES IMIM FUNDACIO INSTITUT MAR D INVESTIGACIONS MEDIQUES IMIM Organization address address: Doctor Aiguader 88 city: BARCELONA postcode: 8003 website: www.imim.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	290˙312.00
11	SOCIETE EUROPEENNE DE CARDIOLOGIE SOCIETE EUROPEENNE DE CARDIOLOGIE Organization address address: ROUTE DES COLLES 2035 city: BIOT SOPHIA ANTIPOLIS postcode: 6903 website: www.escardio.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (BIOT SOPHIA ANTIPOLIS)	participant	268˙171.00
12	EUROPEAN RESUSCITATION COUNCIL EUROPEAN RESUSCITATION COUNCIL Organization address address: EMILE VANDERVELDELAAN 35 city: NIEL postcode: 2845 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (NIEL)	participant	257˙500.00
13	Catalyze B.V. Catalyze B.V. Organization address address: JOOP-GEESINKWEG 167 city: AMSTERDAM-DUIVENDRECHT postcode: 1114 AB website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM-DUIVENDRECHT)	participant	223˙033.00
14	UNIVERSITA DEGLI STUDI DI PAVIA UNIVERSITA DEGLI STUDI DI PAVIA Organization address address: STRADA NUOVA 65 city: PAVIA postcode: 27100 website: www.unipv.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PAVIA)	participant	220˙000.00
15	ZDRAVOTNICKA ZACHRANNA SLUZBA KRALOVEHRADECKEHO KRAJE ZDRAVOTNICKA ZACHRANNA SLUZBA KRALOVEHRADECKEHO KRAJE Organization address address: HRADECKA 1690/2A NOVY HRADEC KRALOVE city: HRADEC KRALOVE postcode: 500 12 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (HRADEC KRALOVE)	participant	136˙937.00
16	PANAXEA BV PANAXEA BV Organization address address: SCIENCE PARK 400 MATRIX II UNIT 3.1 city: AMSTERDAM postcode: 1098 XH website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	130˙062.00
17	DRUG DISCOVERY FACTORY BV DRUG DISCOVERY FACTORY BV Organization address address: JOOP GEESINKWEG 167 city: AMSTERDAM DUIVENDRECHT postcode: 1114 AB website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM DUIVENDRECHT)	participant	74˙091.00
18	UNIVERSITE PARIS DESCARTES UNIVERSITE PARIS DESCARTES Organization address address: RUE DE L ECOLE DE MEDECINE 12 city: PARIS CEDEX 06 postcode: 75270 website: www.univ-paris5.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS CEDEX 06)	participant	0.00

Map

Project objective

Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have been hampered by the lack of sufficiently large study cohorts of SCA patients with detailed information. Obtaining SCA patient samples is challenging as the condition happens suddenly and unexpectedly.

In this project, leading European scientific teams which have created large relevant population cohorts, mostly dedicated to SCA research, join forces to fully exploit available data towards improving SCA management. This will be done by: - Building an unique and growing database of >100.000 (DNA) samples including >20.000 SCA patient samples, by combining existing European databases and infrastructures. - Identifying risk factors (inherited, acquired, environmental) and first-response treatment strategies that may explain the differences in SCA occurrence and survival between European countries - Collaborating with professional networks, such as the European Heart Rhythm Association, and European Resuscitation Council, to translate the outcomes into changes in clinical practice and influencing European health policies on SCA management.

Deliverables

List of deliverables.
Symposia EHRA-ESC	Websites, patent fillings, videos etc.	2020-04-03 13:50:04
Workshop on gender-sensitive health care	Websites, patent fillings, videos etc.	2020-03-04 08:46:49
Project website in place	Websites, patent fillings, videos etc.	2020-03-04 08:46:49

Take a look to the deliverables list in detail: detailed list of ESCAPE-NET deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2017	Niels KjÃ¦r Stampe, Charlotte Glinge, Reza Jabbari, Thea Bjune, Bjarke Risgaard, Jacob Tfelt-Hansen, Bo Gregers Winkel Febrile seizures prior to sudden cardiac death: a Danish nationwide study published pages: f192-f197, ISSN: 1099-5129, DOI: 10.1093/europace/eux335	EP Europace 20/FI2	2020-03-05
2020	Paulien C.M. Homma, Corina de Graaf, Hanno L. Tan, Michiel Hulleman, Rudolph W. Koster, Stefanie G. Beesems, Marieke T. Blom Transfer of essential AED information to treating hospital (TREAT) published pages: 47-52, ISSN: 0300-9572, DOI: 10.1016/j.resuscitation.2020.01.033	Resuscitation 149	2020-03-05
2019	Talip E Eroglu, Grimur H Mohr, Marieke T Blom, Arie O Verkerk, Patrick C Souverein, Christian Torp-Pedersen, Fredrik Folke, Mads Wissenberg, Lettine van den Brink, Richard P Davis, Anthonius de Boer, Gunnar H Gislason, Hanno L Tan Differential effects on out-of-hospital cardiac arrest of dihydropyridines: real-world data from population-based cohorts across two European countries published pages: , ISSN: 2055-6837, DOI: 10.1093/ehjcvp/pvz038	European Heart Journal - Cardiovascular Pharmacotherapy	2020-03-04
2018	Peter J Schwartz, Davide Gentilini Can genetics predict risk for sudden cardiac death? The relentless search for the Holy Grail published pages: 3970-3972, ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehy508	European Heart Journal 39/44	2020-03-04
2020	Gaetano M. De Ferrari, Veronica Dusi, Marta Ruffinazzi, Lucrezia C. Masiello, Enrico Ruffino, Luisa Cacciavillani, Patrizia Noussan, Valerio ZacÃ , Tommaso Sanna, Marina L. Lazzarotti, Tullio Usmiani, Massimiliano Gnecchi, Gianfranco Parati, Lia Crotti, Peter J. Schwartz Risk factors for primary ventricular fibrillation during a first myocardial infarction: Clinical findings from PREDESTINATION (PRimary vEntricular fibrillation and suDden dEath during firST myocardIal iNfArcTION) published pages: 164-170, ISSN: 0167-5273, DOI: 10.1016/j.ijcard.2019.10.060	International Journal of Cardiology 302	2020-03-04
2020	Hanno L Tan, Laura H van Dongen, Dominic S Zimmerman Sudden cardiac death in young patients with diabetes: a call to study additional causes beyond ischaemic heart disease published pages: , ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehaa011	European Heart Journal	2020-03-04
2019	Benjamin P. van Nieuwenhuizen, Iris Oving, Anton E. Kunst, Joost Daams, Marieke T. Blom, Hanno L. Tan, Irene G.M. van Valkengoed Socio-economic differences in incidence, bystander cardiopulmonary resuscitation and survival from out-of-hospital cardiac arrest: A systematic review published pages: 44-62, ISSN: 0300-9572, DOI: 10.1016/j.resuscitation.2019.05.018	Resuscitation 141	2020-03-04
2020	Laura H van Dongen, Marieke T Blom, Abdenasser Bardai, Paulien C M Homma, Joline W J Beulens, Amber A van der Heijden, Petra Elders, Hanno L Tan High haemoglobin A1c level is a possible risk factor for ventricular fibrillation in sudden cardiac arrest among non-diabetic individuals in the general population published pages: , ISSN: 1099-5129, DOI: 10.1093/europace/euz338	EP Europace	2020-03-04
2019	Carlo Alberto Barcella, Grimur H. Mohr, Kristian Kragholm, Paul Blanche, Thomas A. Gerds, Mads Wissenberg, Steen M. Hansen, Kristian Bundgaard, Freddy K. Lippert, Fredrik Folke, Christian Torp-Pedersen, Lars V. Kessing, Gunnar H. Gislason, Kathrine B. SÃ¸ndergaard Out-of-hospital cardiac arrest in patients with psychiatric disorders â€” Characteristics and outcomes published pages: 180-188, ISSN: 0300-9572, DOI: 10.1016/j.resuscitation.2019.07.008	Resuscitation 143	2020-03-04
2019	Carlo Alberto Barcella, Grimur HÃ¸gnason Mohr, Kristian Hay Kragholm, Thomas Alexander Gerds, Svend Eggert Jensen, Christoffer Polcwiartek, Mads Wissenberg, Freddy Knudsen Lippert, Christian Torpâ€Pedersen, Lars Vedel Kessing, Gunnar Hilmar Gislason, Kathrine Bach SÃ¸ndergaard Outâ€ofâ€Hospital Cardiac Arrest in Patients With and Without Psychiatric Disorders: Differences in Use of Coronary Angiography, Coronary Revascularization, and Implantable Cardioverterâ€Defibrillator and Survival published pages: , ISSN: 2047-9980, DOI: 10.1161/JAHA.119.012708	Journal of the American Heart Association 8/16	2020-03-04
2019	Veronica Dusi, Gaetano Maria De Ferrari, Luigi Pugliese, Peter J. Schwartz Cardiac Sympathetic Denervation in Channelopathies published pages: , ISSN: 2297-055X, DOI: 10.3389/fcvm.2019.00027	Frontiers in Cardiovascular Medicine 6	2020-03-04
2019	Rafik Tadros, Hanno L Tan, Sulayman el Mathari, Jan A Kors, Pieter G Postema, Najim Lahrouchi, Leander Beekman, Milena Radivojkov-Blagojevic, Ahmad S Amin, Thomas Meitinger, Michael W Tanck, Arthur A Wilde, Connie R Bezzina Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores published pages: 3097-3107, ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehz435	European Heart Journal 40/37	2020-03-04
2019	Gaetano M. De Ferrari, Veronica Dusi, Marta Ruffinazzi, Vincenzo Gionti, Luisa Cacciavillani, Patrizia Noussan, Valerio ZacÃ , Tommaso Sanna, Lia Crotti, Peter J. Schwartz Physical Inactivity Is a Risk Factor for Primary Ventricular Fibrillation published pages: 2117-2118, ISSN: 0735-1097, DOI: 10.1016/j.jacc.2019.01.063	Journal of the American College of Cardiology 73/16	2020-03-04
2019	Thomas Hadberg Lynge, Jesper Svane, Ulrik Pedersen-Bjergaard, Gunnar Gislason, Christian Torp-Pedersen, Jytte Banner, Bjarke Risgaard, Bo Gregers Winkel, Jacob Tfelt-Hansen Sudden cardiac death among persons with diabetes aged 1â€“49 years: a 10-year nationwide study of 14â€‰294 deaths in Denmark published pages: , ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehz891	European Heart Journal	2020-03-04
2019	Marieke A. R. Bak, M. Corrette Ploem, Hakan AteÅŸyÃ¼rek, Marieke T. Blom, Hanno L. Tan, Dick L. Willems Stakeholdersâ€™ perspectives on the post-mortem use of genetic and health-related data for research: a systematic review published pages: , ISSN: 1018-4813, DOI: 10.1038/s41431-019-0503-5	European Journal of Human Genetics	2020-03-04
2019	Iris Oving, Siobhan Masterson, Ingvild B.M. Tjelmeland, Martin Jonsson, Federico Semeraro, Mattias Ringh, Anatolij Truhlar, Diana Cimpoesu, Fredrik Folke, Stefanie G. Beesems, Rudolph W. Koster, Hanno L. Tan, Marieke T. Blom First-response treatment after out-of-hospital cardiac arrest: a survey of current practices across 29 countries in Europe published pages: , ISSN: 1757-7241, DOI: 10.1186/s13049-019-0689-0	Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 27/1	2020-03-04
2018	Peter J Schwartz, Lia Crotti, Alfred L George Modifier genes for sudden cardiac death published pages: , ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehy502	European Heart Journal	2020-03-04
2018	Mohammad Bakhriansyah, Patrick C Souverein, Olaf H Klungel, Anthonius de Boer, Marieke T Blom, Hanno L Tan Non-steroidal anti-inflammatory drugs and the risk of out-of-hospital cardiac arrest: a caseâ€“control study published pages: 99-105, ISSN: 1099-5129, DOI: 10.1093/europace/euy180	EP Europace 21/1	2020-03-04
2019	Andreu Bofill, Xavier Jalencas, Tudor I. Oprea, Jordi Mestres The human endogenous metabolome as a pharmacology baseline for drug discovery published pages: , ISSN: 1359-6446, DOI: 10.1016/j.drudis.2019.06.007	Drug Discovery Today	2020-03-04
2019	Marieke T Blom, Iris Oving, Jocelyn Berdowski, Irene G M van Valkengoed, Abdenasser Bardai, Hanno L Tan Women have lower chances than men to be resuscitated and survive out-of-hospital cardiac arrest published pages: , ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehz297	European Heart Journal	2020-03-04
2019	Frederik N. Ã…gesen, Peter E. Weeke, Peer Tfelt-Hansen, Jacob Tfelt-Hansen Pharmacokinetic variability of beta-adrenergic blocking agents used in cardiology published pages: e00496, ISSN: 2052-1707, DOI: 10.1002/prp2.496	Pharmacology Research & Perspectives 7/4	2020-03-04
2017	Laura Ruggeri, Federico Semeraro, Giuseppe Ristagno Amplitude spectrum area: The â€œclairvoyanceâ€ during resuscitation in the era of predictive medicine published pages: A5-A6, ISSN: 0300-9572, DOI: 10.1016/j.resuscitation.2017.09.011	Resuscitation 120	2020-03-04
2018	M. Hulleman, M. T. Blom, A. Bardai, H. L. Tan, R. W. Koster Atrial fibrillation mimicking ventricular fibrillation confuses an automated external defibrillator published pages: 281-282, ISSN: 1568-5888, DOI: 10.1007/s12471-018-1098-0	Netherlands Heart Journal 26/5	2020-03-04
2017	Frederik Nybye Ã…gesen, Bjarke Risgaard, SÃ¡ra ZachariasardÃ³ttir, Reza Jabbari, Thomas Hadberg Lynge, Ole Ingemann-Hansen, Gyda Lolk Ottesen, JÃ¸rgen Lange Thomsen, Stig HaunsÃ¸, Derk Wolfgang Krieger, Bo Gregers Winkel, Jacob Tfelt-Hansen Sudden unexpected death caused by stroke: A nationwide study among children and young adults in Denmark published pages: 285-291, ISSN: 1747-4930, DOI: 10.1177/1747493017724625	International Journal of Stroke 13/3	2020-03-04
2018	Hanno L Tan, Nikolaos Dagres, Bernd W BÃ¶ttiger, Peter J Schwartz European Sudden Cardiac Arrest network: towards Prevention, Education and New Effective Treatments (ESCAPE-NET) published pages: 86-88, ISSN: 0195-668X, DOI: 10.1093/eurheartj/ehx758	European Heart Journal 39/2	2020-03-04
2017	Reza Jabbari, Javad Jabbari, Charlotte Glinge, Bjarke Risgaard, Stefan Sattler, Bo Gregers Winkel, Christian Juhl Terkelsen, Hans-Henrik Tilsted, Lisette Okkels Jensen, Mikkel Hougaard, Stig HaunsÃ¸, Thomas EngstrÃ¸m, Christine M. Albert, Jacob Tfelt-Hansen Association of common genetic variants related to atrial fibrillation and the risk of ventricular fibrillation in the setting of first ST-elevation myocardial infarction published pages: , ISSN: 1471-2350, DOI: 10.1186/s12881-017-0497-1	BMC Medical Genetics 18/1	2020-03-04
2018	Marieke A. R. Bak, Marieke T. Blom, Hanno L. Tan, Dick L. Willems Ethical aspects of sudden cardiac arrest research using observational data: a narrative review published pages: , ISSN: 1364-8535, DOI: 10.1186/s13054-018-2153-3	Critical Care 22/1	2020-03-04
2018	Jean-Philippe Empana, Marieke T. Blom, Bernd W. BÓ§ttiger, Nikolaos Dagres, Jacqueline M. Dekker, Gunnar Gislason, Xavier Jouven, Thomas Meitinger, Giuseppe Ristagno, Peter J. Schwartz, Martin Jonsson, Jacob Tfelt-Hansen, Anatolij Truhlar, Hanno L. Tan Determinants of occurrence and survival after sudden cardiac arrestâ€“A European perspective: The ESCAPE-NET project published pages: 7-13, ISSN: 0300-9572, DOI: 10.1016/j.resuscitation.2017.12.011	Resuscitation 124	2020-03-04

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