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IN-PLANTO_CUES TERMINATED
INTEGRATION OF PLANT ORGANELLE COMMUNICATION UNDER ENVIRONMENTAL STRESS
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0IN-PLANTO_CUES project word cloud
Explore the words cloud of the IN-PLANTO_CUES project. It provides you a very rough idea of what is the project "IN-PLANTO_CUES" about.
biosynthetic
stress
signals
plant
phosphate
impose
apparently
collectively
adjustment
death
fundamental
mitochondria
intriguing
drought
negatively
physiological
temperature
transcription
initiator
linked
mechanisms
combine
vib
invoke
trigger
regulated
reveal
cross
mitochondrial
chloroplasts
first
transducer
talk
sal1
components
integration
coordinated
homeostasis
hosts
interaction
levels
pnas
sensing
light
programmed
redox
environmental
function
mobile
opportunity
questions
localized
anac013
crosstalk
cell
tolerance
signal
scales
understand
model
enzyme
exemplar
enhanced
pap
hinting
organelles
consisting
harmonic
phosphoadenosine
multiple
conversely
cellular
enigmatic
signaling
occurs
metabolism
mechanism
nucleus
acclimation
cells
integrate
chloroplast
extremes
oxidative
ing
coordinate
discordant
outcomes
Project "IN-PLANTO_CUES" data sheet
The following table provides information about the project.
| Coordinator |
VIB VZW
Organization address contact info |
| Coordinator Country | Belgium [BE] |
| Total cost | 172˙800 € |
| EC max contribution | 172˙800 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2016 |
| Funding Scheme | MSCA-IF-EF-ST |
| Starting year | 2018 |
| Duration (year-month-day) | from 2018-03-12 to 2020-03-11 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | VIB VZW | BE (ZWIJNAARDE - GENT) | coordinator | 172˙800.00 |
Map
Project objective
Environmental challenges such as drought, temperature and light extremes can impose oxidative stress in multiple organelles, thus negatively affecting the function of plant cells. Both chloroplasts and mitochondria can invoke signaling pathways to the nucleus that trigger stress responses and adjustment of cellular homeostasis, resulting in physiological outcomes such as enhanced stress tolerance, or conversely programmed cell death. These pathways include the 3'-phosphoadenosine 5'-phosphate (PAP)-SAL1 pathway for chloroplasts and the ANAC013 mobile transcription factor for mitochondria. However, the mechanisms by which plant cells coordinate different signals from chloroplasts and mitochondria for whole-cell acclimation to oxidative stress are still enigmatic. Whether there is any cross-talk between chloroplast and mitochondrial signaling is also intriguing. My project will investigate these fundamental questions using an exemplar model system consisting of three components that combine my research with the Hosts’. The first goal is to take my PNAS findings that SAL1 is a redox-regulated initiator of chloroplast signaling and determine if a similar mechanism occurs in the mitochondria, where SAL1 is also localized. This would reveal how two distinct organelles can integrate oxidative stress sensing and response by using the same pathway. Second, the interaction between SAL1-redox sensing and the mitochondrial signaling transducer ANAC013 will be investigated to understand integration between these two apparently distinct pathways. Third, ANAC013 targets a biosynthetic enzyme for PAP hinting at crosstalk between mitochondrial and chloroplast signaling at the level of signal metabolism. Thus, my research on SAL1-PAP and VIB’s on ANAC013 collectively present a unique opportunity to reveal how the two pathways are linked at different levels enabling cellular signaling to be coordinated across scales to facilitate a harmonic, not discordant acclimation response.
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The information about "IN-PLANTO_CUES" are provided by the European Opendata Portal: CORDIS opendata.
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