Explore the words cloud of the EbolaMoDRAD project. It provides you a very rough idea of what is the project "EbolaMoDRAD" about.
The following table provides information about the project.
Coordinator |
FOLKHALSOMYNDIGHETEN
Organization address contact info |
Coordinator Country | Sweden [SE] |
Project website | http://www.ebolamodrad.eu/ |
Total cost | 4˙300˙935 € |
EC max contribution | 4˙300˙935 € (100%) |
Programme |
1. H2020-EU.3.1.7. (Innovative Medicines Initiative 2 (IMI2)) |
Code Call | H2020-JTI-IMI2-2014-02-single-stage |
Funding Scheme | IMI2-RIA |
Starting year | 2015 |
Duration (year-month-day) | from 2015-02-01 to 2018-01-31 |
Take a look of project's partnership.
The current Ebola Virus Disease (EVD) outbreak has caused more than 5000 deaths within a few months in West Africa (Guinea, Sierra Leone and Liberia being the most severely affected countries), including numerous healthcare workers. It is now is serious public health crisis of international concern . The numbers of cases are still increasing 11 months after the first case was described (December 2013), by mid November 2014 approximately 15000 individuals have been infected and the epidemic is still not under control The direct effects of this outbreak include disruption of standard medical care, insecurity and social disruption in countries that were already struggling to recover from decades of war. One of the most important key actions to limit and stop the spread of this deadly disease is to identify and isolate the EBOV-infected patients. The diagnosis of Ebola Virus infections has in the past, been performed overwhelmingly in specialist reference laboratories with high-performance molecular, serological and culture methods.In recent years many of these functions have been mobilised into rapid response mobile laboratories, indeed several of these units supported by, European, CDC/USA, Canadian, Chinese and African states have been set up to help in the current outbreak by performing laboratory diagnosis, in collaboration with national centres in West Africa. While this type of response has been effective in helping control past EVD outbreaks in rural parts of Africa, it has not been as effective at controlling the current outbreak which is now spreading in densely populated city and slum areas. Unfortunately, the diagnostic procedures currently used in the mobile laboratories are associated with several problems: i) there are a limited number of diagnostic hubs, ii) performing the diagnostic tests correctly requires specialist training, skill and experience, consequently there a limited numbers of trained staff
Field usable filer tipp based RNA extraction | Demonstrators, pilots, prototypes | 2019-06-19 14:40:34 |
Validation and field trials report | Documents, reports | 2019-06-19 14:40:34 |
Validate QRT-PCR assays | Documents, reports | 2019-06-19 14:40:34 |
Report on course/workshop on outbreak management | Documents, reports | 2019-06-19 14:40:34 |
Report on course/workshop in field diagnostic | Documents, reports | 2019-06-19 14:40:34 |
Report on course/workshop on clinical aspects of emerging disease | Documents, reports | 2019-06-19 14:40:34 |
Design, develop and validate isothermal detection assays based on RPA, LAMP and hRCA technology | Documents, reports | 2019-06-19 14:40:34 |
Design, develop and validate Ebola detection in an automated and closed system | Demonstrators, pilots, prototypes | 2019-06-19 14:40:34 |
Take a look to the deliverables list in detail: detailed list of EbolaMoDRAD deliverables.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
F. Colavita, M. Biava, P. Mertens, Q. Gilleman, C. Borlon, M. Delli Guanti, A. Petrocelli, G. Cataldi, A.T. Kamara, S.A. Kamara, K. Konneh, D. Vincenti, C. Castilletti, S. Abdurahman, A. Mirazimi, M.R. Capobianchi, G. Ippolito, R. Miccio, A. Di Caro EBOLA Ag K -SeT rapid test: field evaluation in Sierra Leone published pages: 653-657, ISSN: 1198-743X, DOI: 10.1016/j.cmi.2017.10.019 |
Clinical Microbiology and Infection 24/6 | 2019-06-19 |
2017 |
Christian Risinger, Kasper K. Sørensen, Knud J. Jensen, Sigvard Olofsson, Tomas Bergström, Ola Blixt Linear Multiepitope (Glyco)peptides for Type-Specific Serology of Herpes Simplex Virus (HSV) Infections published pages: 360-367, ISSN: 2373-8227, DOI: 10.1021/acsinfecdis.7b00001 |
ACS Infectious Diseases 3/5 | 2019-06-19 |
2017 |
Felix He, Krister Melén, Sari Maljanen, Rickard Lundberg, Miao Jiang, Pamela Österlund, Laura Kakkola, Ilkka Julkunen Ebolavirus protein VP24 interferes with innate immune responses by inhibiting interferon-λ1 gene expression published pages: 23-34, ISSN: 0042-6822, DOI: 10.1016/j.virol.2017.06.002 |
Virology 509 | 2019-06-19 |
2017 |
Géraldine Piorkowski, Frédéric Jacquot, Gilles Quérat, Caroline Carbonnelle, Delphine Pannetier, France Mentré, Hervé Raoul, Xavier de Lamballerie Implementation of a non-human primate model of Ebola disease: Infection of Mauritian cynomolgus macaques and analysis of virus populations published pages: 95-105, ISSN: 0166-3542, DOI: 10.1016/j.antiviral.2017.01.017 |
Antiviral Research 140 | 2019-06-19 |
2018 |
M. Biava, F. Colavita, A. Marzorati, D. Russo, D. Pirola, A. Cocci, A. Petrocelli, M. Delli Guanti, G. Cataldi, T.A. Kamara, A.S. Kamara, K. Konneh, A. Cannas, S. Coen, S. Quartu, S. Meschi, M.B. Valli, A. Mazzarelli, C. Venditti, G. Grassi, G. Rozera, C. Castilletti, A. Mirazimi, M.R. Capobianchi, G. Ippolito, R. Miccio, A. Di Caro Evaluation of a rapid and sensitive RT-qPCR assay for the detection of Ebola Virus published pages: 70-74, ISSN: 0166-0934, DOI: 10.1016/j.jviromet.2017.11.009 |
Journal of Virological Methods 252 | 2019-06-19 |
2017 |
Jorma Hinkula, Stéphanie Devignot, Sara Åkerström, Helen Karlberg, Eva Wattrang, Sándor Bereczky, Mehrdad Mousavi-Jazi, Christian Risinger, Gunnel Lindegren, Caroline Vernersson, Janusz Paweska, Petrus Jansen van Vuren, Ola Blixt, Alejandro Brun, Friedemann Weber, Ali Mirazimi Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice published pages: e02076-16, ISSN: 0022-538X, DOI: 10.1128/JVI.02076-16 |
Journal of Virology 91/10 | 2019-06-19 |
2017 |
S. Carinelli, M. Kühnemund, M. Nilsson, M.I. Pividori Yoctomole electrochemical genosensing of Ebola virus cDNA by rolling circle and circle to circle amplification published pages: 65-71, ISSN: 0956-5663, DOI: 10.1016/j.bios.2016.09.099 |
Biosensors and Bioelectronics 93 | 2019-06-19 |
2018 |
Jérémie Guedj, Géraldine Piorkowski, Frédéric Jacquot, Vincent Madelain, Thi Huyen Tram Nguyen, Anne Rodallec, Stephan Gunther, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques published pages: e1002535, ISSN: 1549-1676, DOI: 10.1371/journal.pmed.1002535 |
PLOS Medicine 15/3 | 2019-06-19 |
2017 |
Tomasz Krzywkowski, Mats Nilsson Fidelity of RNA templated end-joining by chlorella virus DNA ligase and a novel iLock assay with improved direct RNA detection accuracy published pages: e161-e161, ISSN: 0305-1048, DOI: 10.1093/nar/gkx708 |
Nucleic Acids Research 45/18 | 2019-06-19 |
2018 |
Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, Ola Blixt A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer published pages: e0191872, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0191872 |
PLOS ONE 13/2 | 2019-06-19 |
2017 |
Malte Kühnemund, Iván Hernández-Neuta, Mohd Istiaq Sharif, Matteo Cornaglia, Martin A.M. Gijs, Mats Nilsson Sensitive and inexpensive digital DNA analysis by microfluidic enrichment of rolling circle amplified single-molecules published pages: gkw1324, ISSN: 0305-1048, DOI: 10.1093/nar/gkw1324 |
Nucleic Acids Research 45(8) | 2019-06-19 |
2017 |
Nicolai Stuhr-Hansen, Christian Risinger, Ebbe Engholm, Ola Blixt Synthesis of Oligo-(alkyne-triplet)peptide Constructs published pages: 6522-6525, ISSN: 1523-7060, DOI: 10.1021/acs.orglett.7b03231 |
Organic Letters 19/24 | 2019-06-19 |
2017 |
Francesca Colavita, Mirella Biava, Concetta Castilletti, Serena Quartu, Francesco Vairo, Claudia Caglioti, Chiara Agrati, Eleonora Lalle, Licia Bordi, Simone Lanini, Michela Delli Guanti, Rossella Miccio, Giuseppe Ippolito, Maria R. Capobianchi, Antonino Di Caro Measles Cases during Ebola Outbreak, West Africa, 2013–2106 published pages: 1035-1037, ISSN: 1080-6040, DOI: 10.3201/eid2306.161682 |
Emerging Infectious Diseases 23/6 | 2019-06-19 |
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The information about "EBOLAMODRAD" are provided by the European Opendata Portal: CORDIS opendata.
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