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Motivageing SIGNED

Motivation–cognition interaction in healthy ageing and Parkinson’s disease

Total Cost €

EC-Contrib. €

Partnership

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Motivageing project word cloud

Explore the words cloud of the Motivageing project. It provides you a very rough idea of what is the project "Motivageing" about.

plan memory trial innovative cognition greying mechanisms interaction drug pd functional adults affective parkinson neural motivageing population proposing neuroscience wm conduct older investigates pathological clinicians deficits framework clinical efficacy behavioural patients disease cognitive entire tested disorders first scientific dementia time relation helping extend function neuropsychology gaps understand europe randomised quality capacity employs social training issue enhancement decline motivation neurodegenerative procedure enormous filling multidisciplinary wellbeing multimodal pharmacological treat people society life healthy ageing union treatment foundation theory economic valuable employed theoretical model fact neuroimaging mocoint age interdisciplinary posed

Project "Motivageing" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY OF KEELE Organization address address: KEELE UNIVERSITY FINANCE DPT city: KEELE postcode: ST5 5BG website: www.keele.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	251˙857 €
EC max contribution	251˙857 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2016
Funding Scheme	MSCA-IF-GF
Starting year	2018
Duration (year-month-day)	from 2018-02-01 to 2021-01-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY OF KEELE UNIVERSITY OF KEELE Organization address address: KEELE UNIVERSITY FINANCE DPT city: KEELE postcode: ST5 5BG website: www.keele.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (KEELE)	coordinator	251˙857.00
2	THE WASHINGTON UNIVERSITY CORPORATION THE WASHINGTON UNIVERSITY CORPORATION Organization address address: Office of Sponsored Research Services -One Brookings Drive city: ST LOUIS postcode: MO 63130-4899 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (ST LOUIS)	partner	0.00

Map

Project objective

Europe is greying. This has enormous economic and social costs for the entire society, through greater numbers of healthy older adults with cognitive decline, and of people with neurodegenerative disorders that can lead to dementia, such as Parkinson’s disease (PD). MOTIVAGEING aims to address this issue by proposing a new approach for the enhancement of working memory (WM) capacity, in order to improve cognitive function, quality of life and wellbeing of healthy older adults and PD patients. In fact, there is no current effective treatment for age-related WM decline or WM deficits and related behavioural and affective problems in PD patients. Based on a promising new theory of cognitive neuroscience, the Motivation-Cognition Interaction (MoCoInt) framework, the present plan employs an interdisciplinary approach: in Study 1, an innovative multimodal functional neuroimaging method is proposed to analyse for the first time the neural mechanisms of MoCoInt in healthy ageing. The new evidence will provide a foundation for Study 2, in which the efficacy of a novel WM training procedure, based on MoCoInt, will be tested in healthy older adults in order to improve their WM capacity. Finally, to understand if this new training procedure can be employed to treat WM deficits in PD, Study 3 investigates for the first time MoCoInt mechanisms in PD patients in relation to pharmacological treatment, through the conduct of a randomised controlled drug trial. Results will enable to extend MoCoInt to healthy and pathological ageing, and to develop a new framework that will be available as a new theoretical model for both researchers and clinicians. MOTIVAGEING will therefore have both a significant scientific multidisciplinary impact, filling several gaps in knowledge in cognitive neuroscience, cognitive and clinical neuropsychology, and a valuable social and economic impact in the European Union, helping to address the crucial issues posed by the ageing population.

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The information about "MOTIVAGEING" are provided by the European Opendata Portal: CORDIS opendata.