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FLUINEMS SIGNED

Suspended Fluidic nanochannels as optomechanical sensors for single molecules

Total Cost €

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EC-Contrib. €

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Partnership

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 FLUINEMS project word cloud

Explore the words cloud of the FLUINEMS project. It provides you a very rough idea of what is the project "FLUINEMS" about.

medicine    molecules    relevance    university    10    solution    chip    preventive    spectroscopy    rate    iof    microrna    detects    concentrations    fresh    environments    purified    raman    expert    bioapplications    cancers    benefited    earlier    nanoengineering    water    starting    integrate    monitoring    90    molecule    events    dr    hamburg    proof    counts    became    extremely    nanotechnology    survival    identifies    oncoviruses    instrumentation    diagnosing    diffraction    platform    physics    clinical    nanochannels    expertise    cheap    ideal    discard    there    cuesta    sensing    single    nanofabrication    molecular    one    environmental    usually    worked    optical    variety    start    antennas    founder    environment    plasmonic    early    versatile    screening    fernandez    detect    nano    multiple    biotoxins    co    plasmonics    capsides    lack    lives    suspend    international    novelty    plasma    curie    mass    interdisciplinary    biomarkers    collaborators    detection    protein    universal    types    klinikum    counted    marie    saves    recognition    binding    eppendorf    combined    she    bio    biochemical    smart    cancer    concentration    ceo   

Project "FLUINEMS" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAET HAMBURG 

Organization address
address: MITTELWEG 177
city: HAMBURG
postcode: 20148
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.ifc-lab.com
 Total cost 1˙500˙000 €
 EC max contribution 1˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-STG
 Funding Scheme ERC-STG
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2022-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAET HAMBURG DE (HAMBURG) coordinator 1˙500˙000.00

Map

 Project objective

Early detection of cancer saves lives: the survival rate increases from 10% to 90%. Today, there is a lack of methods for the early detection of different types of cancer. The main challenge is that a large variety of specific biomarkers have to be counted, and usually at extremely low concentrations. Here we will use smart nanoengineering to develop a versatile sensing platform that detects, identifies and counts single molecules, one by one, in a non-purified solution. The main novelty of the proposal is that the platform will integrate optical sensing beyond diffraction (for biochemical recognition) and on-chip molecular mass sensing (to discard non-specific binding events). For this, we will suspend state-of-the-art nanochannels and integrate them with plasmonic nano-antennas. This will make for a versatile, universal test, cheap enough to be used for preventive screening. It will help diagnosing different types of cancers earlier. We will detect and identify oncoviruses capsides, different protein biomarkers and microRNA in plasma. These are very high impact proof of concepts with clinical relevance. Dr. Fernandez-Cuesta has expertise in single molecule sensing and has worked in multiple international, interdisciplinary environments. She is expert in nanofabrication and plasmonics for (bio)sensing. She benefited from an IOF Marie Curie. She became CEO and co-founder of a start-up, dedicated to on-chip Raman spectroscopy for environmental monitoring of biotoxins concentration in fresh water. Currently, she is at the department for Applied Physics at the University of Hamburg. There, there is state-of-the-art instrumentation for nanofabrication. The collaborators at Hamburg University Klinikum Eppendorf have expertise in applying research to medicine. This interdisciplinary environment is ideal for starting a new field in combined plasmonics and mass sensing with a focus on nanotechnology for bioapplications of clinical relevance.

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The information about "FLUINEMS" are provided by the European Opendata Portal: CORDIS opendata.

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