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KardiaTool SIGNED

An integrated POC solution for non-invasive diagnosis and therapy monitoring of Heart Failure patients

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

KardiaTool project word cloud

Explore the words cloud of the KardiaTool project. It provides you a very rough idea of what is the project "KardiaTool" about.

hf acceptable probnp community point beneficial added microelectromechanical outcomes platform integrate professionals predictive validate gcp clinical quantitative setting electronics nanoparticles micro onto monitoring software laboratory techniques mnps interleukin biomarker convenient data analyzes samples industrialize magnetic marketization lays loc glp portable diagnostics biosensor mems bio kardiapoc disposable qualitative proven therapy device decision personalized kardiasoft arena lab blood invasive healthcare nt gmp delivers simultaneously capability tnf translate saliva patients poc accurate innovation rapid variety chemicals chip functionalized source kardiatool actuators incorporation extracting diagnosis mnbs patient progress biomarkers care sensors cortisol

Project "KardiaTool" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITE LYON 1 CLAUDE BERNARD Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43 city: VILLEURBANNE CEDEX postcode: 69622 website: www.univ-Iyon1.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	http://www.kardiatool.eu/
Total cost	4˙999˙880 €
EC max contribution	4˙999˙880 € (100%)
Programme	1. H2020-EU.2.1.1.1. (A new generation of components and systems: Engineering of advanced embedded and energy and resource efficient components and systems) 2. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
Code Call	H2020-NMBP-X-KET-2017
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-11-01 to 2021-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITE LYON 1 CLAUDE BERNARD UNIVERSITE LYON 1 CLAUDE BERNARD Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43 city: VILLEURBANNE CEDEX postcode: 69622 website: www.univ-Iyon1.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (VILLEURBANNE CEDEX)	coordinator	446˙132.00
2	IDRYMA TECHNOLOGIAS KAI EREVNAS IDRYMA TECHNOLOGIAS KAI EREVNAS Organization address address: N PLASTIRA STR 100 city: IRAKLEIO postcode: 70013 website: www.forth.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (IRAKLEIO)	participant	588˙750.00
3	INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM Organization address address: KAPELDREEF 75 city: LEUVEN postcode: 3001 website: www.imec.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	participant	470˙325.00
4	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	467˙612.00
5	MICRONIT MICROTECHNOLOGIES BV MICRONIT MICROTECHNOLOGIES BV Organization address address: COLOSSEUM 15 city: ENSCHEDE postcode: 7521 PV website: www.micronit.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ENSCHEDE)	participant	424˙633.00
6	VALOTEC VALOTEC Organization address address: 1 MAIL DU PROFESSEUR GEORGES MATHE city: VILLEJUIF postcode: 94800 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (VILLEJUIF)	participant	401˙562.00
7	FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Organization address address: HANSASTRASSE 27C city: MUNCHEN postcode: 80686 website: www.fraunhofer.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	participant	399˙375.00
8	ENACHIP INC ENACHIP INC Organization address address: 1 RIGHTER PARKWAY SUITE 260 city: WILMINGTON postcode: 19803 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (WILMINGTON)	participant	392˙500.00
9	UNIVERSITY OF SURREY UNIVERSITY OF SURREY Organization address address: Stag Hill city: GUILDFORD postcode: GU2 7XH website: www.surrey.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (GUILDFORD)	participant	294˙871.00
10	ECOLE NORMALE SUPERIEURE DE LYON ECOLE NORMALE SUPERIEURE DE LYON Organization address address: PARVIS RENE DESCARTES 15 city: LYON postcode: 69342 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (LYON)	participant	219˙319.00
11	BIOTRAY BIOTRAY Organization address address: 82 RUE CYPRIAN city: VILLEURBANNE postcode: 69100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (VILLEURBANNE)	participant	218˙750.00
12	UNIVERSITA DI PISA UNIVERSITA DI PISA Organization address address: LUNGARNO PACINOTTI 43/44 city: PISA postcode: 56126 website: www.unipi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PISA)	participant	191˙250.00
13	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Organization address address: BELFIELD city: DUBLIN postcode: 4 website: www.ucd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	168˙802.00
14	PANEPISTIMIO IOANNINON PANEPISTIMIO IOANNINON Organization address address: PANEPISTEMIOYPOLE PANEPISTEMIO IOANNINON city: IOANNINA postcode: 45110 website: www.uoi.gr / www.rc.uoi.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (IOANNINA)	participant	160˙000.00
15	CONSIGLIO NAZIONALE DELLE RICERCHE CONSIGLIO NAZIONALE DELLE RICERCHE Organization address address: PIAZZALE ALDO MORO 7 city: ROMA postcode: 185 website: www.cnr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	155˙995.00

Map

Project objective

The aim of the KardiaTool project is to translate a laboratory proven concept of a saliva biosensor to the clinical practice for addressing the priority needs in personalized HF diagnostics and therapy monitoring at the point of care. The KardiaTool platform includes: (i) An easy to use portable POC device (KardiaPOC) with a disposable Lab-on-a-Chip (LOC), for the non-invasive, rapid and accurate qualitative and quantitative assessment of HF biomarkers, from saliva samples. KardiaPOC device will integrate a variety of sensors, actuators, Microelectromechanical systems (MEMS), micro-electronics, bio-chemicals and functionalized magnetic nanoparticles (MNPs), onto a disposable, low cost LOC. (ii) A decision support software (KardiaSoft) based on predictive modelling techniques, that analyzes the POC data and other patient’s data, directly added by the healthcare professionals, and delivers information related to HF diagnosis and therapy monitoring. The innovation lays in the incorporation of four novel saliva biomarkers that have been proven in a laboratory setting and bring a new promising concept for addressing the priority needs of the clinical arena. KardiaPOC will provide the capability of simultaneously extracting key information from the saliva biomarkers: (i) NT-proBNP, (ii) TNF-a, (iii) Interleukin- 10, (iv) Cortisol. It is expected that identifying a comparable source to blood, for biomarker information, such as saliva, that is cost effective, less invasive, more convenient and acceptable for both patients and healthcare professionals would be beneficial for the healthcare community. The challenge of KardiaTool is: (i) to translate a laboratory proven concept of a saliva biosensor into an MNBS platform, for HF diagnostics and therapy monitoring, at the point of care, following GLP (ii) to validate the MNBS platform through pre-clinical and clinical testing following GCP and (iii) to industrialize the outcomes following GMP towards progress to marketization

Deliverables

List of deliverables.
Dissemination plan and activities	Documents, reports	2019-09-09 15:39:19
Project website	Websites, patent fillings, videos etc.	2019-09-09 15:39:19

Take a look to the deliverables list in detail: detailed list of KardiaTool deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Lassaad Barhoumi, Francesca Bellagambi, Federico Vivaldi, Abdoullatif Baraket, Yohann ClÃ©ment, Nadia Zine, Mounir Ben Ali, Abdelhamid Elaissari, Abdelhamid Errachid Ultrasensitive Immunosensor Array for TNF-Î± Detection in Artificial Saliva using Polymer-Coated Magnetic Microparticles onto Screen-Printed Gold Electrode published pages: 692, ISSN: 1424-8220, DOI: 10.3390/s19030692	Sensors 19/3	2019-09-09
2018	Abhishek Sonu, Abdoullatif Baraket, Selim Boudjaoui, Juan Gallardo, Nadia Zine, Monique Sigaud, Marie Hangouet, Albert AlcÃ¡cer, Angelos Streklas, Joan Bausells, Abdelhamid Errachid Solid State Gas Sensor Based on Polyaniline Doped with [3,3â€²-Co(1,2-C2B9H11)2]âˆ’1 for Detection of Acetone: Diagnostic to Heart Failure Disease published pages: 1086, ISSN: 2504-3900, DOI: 10.3390/proceedings2131086	Proceedings 2/13	2019-09-09
2018	Elkahina Ghedir, Abdoullatif Baraket, Souad Kouchar, Selma Rabai, Messaoud Benounis, Albert Alcacer, Angelos Streklas, Joan Bausells, Nadia Zine, Nicole Jaffrezic, Abdelhamid Errachid Electrochemical Immunosensor for NT-proBNP Detection in Artificial Human Saliva: Heart Failure Biomedical Application published pages: 1085, ISSN: 2504-3900, DOI: 10.3390/proceedings2131085	Proceedings 2/13	2019-09-09

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The information about "KARDIATOOL" are provided by the European Opendata Portal: CORDIS opendata.