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CISTEM SIGNED

Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine

Total Cost €

EC-Contrib. €

Partnership

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CISTEM project word cloud

Explore the words cloud of the CISTEM project. It provides you a very rough idea of what is the project "CISTEM" about.

vivo children expertise life investigation reaching personalized mimic convey stem many medicine engineering health rare fundamentals too micro orphan date inspired models construct pluripotent patients majority disease organs cells screening superb mechanisms synergistically human platform drugs ipscs treatment academic whom quality functions complementary environment miniaturized diseases source packages threatening staff precise synergies tool organ limited patient microfluidic precision chronic directions public powerful secondments chip separately industrial variability architecture matched drug discovery burning manner cistem

Project "CISTEM" data sheet

The following table provides information about the project.

Coordinator	BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS Organization address address: DR ZORANA DINDICA STREET 1 city: NOVI SAD postcode: 21000 website: www.biosense.rs contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Serbia [RS]
Total cost	364˙500 €
EC max contribution	364˙500 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2017
Funding Scheme	MSCA-RISE
Starting year	2018
Duration (year-month-day)	from 2018-01-01 to 2021-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS Organization address address: DR ZORANA DINDICA STREET 1 city: NOVI SAD postcode: 21000 website: www.biosense.rs contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RS (NOVI SAD)	coordinator	198˙000.00
2	UNIVERSIDAD DE ZARAGOZA UNIVERSIDAD DE ZARAGOZA Organization address address: CALLE PEDRO CERBUNA 12 city: ZARAGOZA postcode: 50009 website: www.unizar.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (ZARAGOZA)	participant	67˙500.00
3	UNIWERSYTET JAGIELLONSKI UNIWERSYTET JAGIELLONSKI Organization address address: Ul. Golebia 24 city: KRAKOW postcode: 31007 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (KRAKOW)	participant	40˙500.00
4	BEONCHIP SL BEONCHIP SL Organization address address: EDIFICIO CEMINEN SPINUP S/N, CALLE MARIANO ESQUILL CAMPUS UNIVERSITARIO RIO EBRO city: ZARAGOZA postcode: 50018 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (ZARAGOZA)	participant	27˙000.00
5	ELVESYS ELVESYS Organization address address: 1-3 BIS RUE ROBERT ET SONIA DELAUNAY city: PARIS postcode: 75011 website: www.elvesys.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	18˙000.00
6	CHERRY BIOTECH CHERRY BIOTECH Organization address address: 6 RUE GURVAND city: RENNES postcode: 35000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (RENNES)	participant	13˙500.00
7	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY Organization address address: RUTGERS PLAZA 3 city: NEW BRUNSWICK postcode: 8901 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (NEW BRUNSWICK)	partner	0.00
8	UNIVERSIDAD DE BUENOS AIRES UNIVERSIDAD DE BUENOS AIRES Organization address address: CALLE VIAMONTE 430 city: BUENOS AIRES postcode: 1053 website: www.uba.ar contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AR (BUENOS AIRES)	partner	0.00

Map

Project objective

Many rare diseases cause chronic health problems or are even life-threatening. The impact on the quality of life of affected patients, of whom many are children, is significant. To date, a limited but increasing number of so-called orphan drugs (drugs for rare diseases) are reaching patients. However, the majority of rare diseases are still without any effective treatment. The development of novel human systems for drug discovery therefore represents a major public health priority. Microfluidic technology-based “Organs-on-a-chip” represents a powerful tool for investigating rare disease mechanisms and testing new drug and treatment due to their ability to mimic tailored micro-environment architecture inspired by organ-level functions in vivo. However, due to the variability in rare disease mechanisms from one patient to another, organ on chip technology needs to be more precise and to convey towards personalized medicine. The human-induced pluripotent stem cells (iPSCs) have a strong potential in engineering organ-on-a-chip since they are derived in a patient-matched manner which makes them a superb source to construct human models for personalized drug screening as well as for understanding patient-specific fundamentals of diseases. To provide novel miniaturized platform for investigation of rare diseases able to address the burning issues in precision medicine today, CISTEM will bring together and synergistically several highly promising research directions which are too often investigated separately at the academic level but also at the industrial level. Based on 4 work packages, the CISTEM RISE project will be implemented by exploiting the complementary expertise of its partners and creating synergies between them through the targeted secondments of staff.

Deliverables

List of deliverables.
Communication and public engagement plan No. 1	Documents, reports	2020-02-18 11:09:43
Project website	Websites, patent fillings, videos etc.	2020-02-18 11:09:43

Take a look to the deliverables list in detail: detailed list of CISTEM deliverables.

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The information about "CISTEM" are provided by the European Opendata Portal: CORDIS opendata.