The page lists 141 projects related to the topic "pluripotent".
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1 | REPROWORM | Safeguarding Cell Identities: Mechanisms Counteracting Cell Fate Reprogramming | 2015 |
2 | Biorapid | Rapid Bioprocess Development | 2015 |
3 | Accellta | Accellta Market Study | 2014 |
4 | MitSyn | Alpha-synuclein and mitochondrial dysfunction: key links between Gaucher’s disease and Parkinson’s? | 2015 |
5 | fetISC | Characterizing drivers of intestinal tissue maturation in vitro and in vivo | 2016 |
6 | 7DUP | Characterization of 7q11.23 reciprocal aneusomy syndromes: from patients to functional pathways (and back) | 2016 |
7 | Oncoworm | ONCOWORM: Using functional genomics in highly regenerative flatworms to find novel cancer genes | 2016 |
8 | VCSD | Visualising Chromatin Structure and Dynamics at the Nanometre Scale with Super-Resolution Fluorescence Microscopy | 2016 |
9 | DecipherBILU | Understanding functional mechanisms leading to the BILU syndrome | 2015 |
10 | LiVirIn | 3D Liver Organoids: Modelling Host Hepatitis B Virus Interaction | 2015 |
11 | RejuvenateBone | Enhancing the regeneration of bone defects in elderly: Rejuvenation of bone microenvironment | 2015 |
12 | embryonic rosettes | Investigating embryonic development at the time of implantation using embryos and ES cells | 2016 |
13 | CARiPSCTcells | Generation of safe and efficient, off-the-shelf, chimeric antigen receptor (CAR)-engineered T cells for broad application | 2015 |
14 | GLYCODIS3 | Genetic correction of glycogen debranching enzyme deficiency in Glycogen Storage disease III: a proof of concept study | 2016 |
15 | POSEIDON | novel bioreactor Platform for reprOducible, Scalable ExpansIonand cardiac DifferentiatiON of hiPSC in suspension culture | 2015 |
16 | CARDIOTOX | Predicting Cardiotoxicity Induced by Kinase Inhibitors: From Systems Biology to Systems Pharmacology | 2015 |
17 | 3Dconvert | The dynamics of the mammalian epigenome during transcription factor-induced cell fate conversion | 2015 |
18 | DRIVE | Diabetes Reversing Implants with enhanced Viability and long-term Efficacy | 2015 |
19 | NeuroInCellNMR | In-cell NMR monitoring of alpha-Synuclein aggregation in neuronal cells | 2015 |
20 | INTRASTEM | INTRASTEM: High Efficiency Delivery of Proteins, Nucleic Acids and Particles to Human Cells | 2015 |
21 | PROMETHEUS | Novel Cells for Organ Repair | 2015 |
22 | NANOBUBBLE | Laser-induced vapour nanobubbles for intracellular delivery of nanomaterials and treatment of biofilm infections | 2015 |
23 | dynamicmodifications | Complexity and dynamics of nucleic acids modifications in vivo | 2015 |
24 | STEMCARDIORISK | Stem Cells for Cardiac Arrhythmia Risk Assessment | 2015 |
25 | REGMAMKID | How to regenerate the mammalian kidney | 2015 |
26 | DeFiNER | Nucleotide Excision Repair: Decoding its Functional Role in Mammals | 2016 |
27 | CELLPLASTICITY | New Frontiers in Cellular Reprogramming: Exploiting Cellular Plasticity | 2015 |
28 | VESCEL | Vascular Engineering on chip using differentiated Stem Cells | 2015 |
29 | MASCP | Mechanisms of alternative pre-mRNA splicing regulation in cancer and pluripotent cells | 2015 |
30 | BetaCellTherapy | Beta Cell Generation by Stem Cell-Derived Implants in Diabetes | 2015 |
31 | TrainMALTA | Interdisciplinary Training in High-Throughput Sequencing, Bioinformatics and Model Systems: Moving towards Clinical applications of Genomics | 2016 |
32 | FAST-DEVELOPS | Developing new therapeutics for Friedreich ataxia | 2015 |
33 | BATCure | Developing new therapies for Batten disease | 2016 |
34 | TECHNOBEAT | Tools and TECHNOlogies for Breakthrough in hEArt Therapies | 2016 |
35 | SysMedPD | Systems Medicine of Mitochondrial Parkinson’s Disease | 2015 |
36 | StemBAT | New players in human BAT differentiation and activation: a human PSC-derived BAT approach combined with state of the art genome engineering and –omics based methodologies | 2016 |
37 | SEARMET | Scientific Excellence in Animal Reproductive Medicine and Embryo Technology | 2016 |
38 | ProNeurons | Transcription Factor-mediated Neuronal Cell Fate Programming in Human Stem Cells | 2016 |
39 | ENHANCE | Engineering the 3D Niche to enHANCE functionality of hepatocytes derived from human iPSCs | 2016 |
40 | DISSection | Doctoral Industrial School on Human Skin models for Staphylococcal infections | 2016 |
41 | ReachingCompleteness | The Molecular Basis of Somatic Nuclear Reprogramming | 2016 |
42 | MIRNANO | Multifunctional miRNA-targeting nanodevices for pluripotent cancer theranostics | 2017 |
43 | ENDYVE | ENgineering DYnamic ViscoElasticity to study cell response | 2016 |
44 | GRNHairCell | Understanding the Gene Regulatory Network involved inner ear Hair Cell differentiation | 2016 |
45 | CAMEOS | Cardiac micro-engineered tissue for high-throughput screening | 2016 |
46 | EHT-CaMKII | CaMKII over stimulation in engineered heart tissues (EHTs) made from human induced pluripotent stem cells (hiPSCs): a parameter involved in the immaturity of hiPSC EHTs cardiomyocytes? | 2016 |
47 | CAiPSC | Determining centromere assembly mechanisms and improving mitotic fidelity during somatic cell reprogramming | 2016 |
48 | DeCISIoN | Drug CandIdates ScreenINg | 2016 |
49 | StemHealth | Foetal Intestinal Stem Cells in Biology and Health | 2016 |
50 | Relieve-Chol | Reprogramming cell identity to develop new therapies against Cholangiopathies | 2016 |
51 | iPSCAtaxia | An induced pluripotent stem cell-based neuronal model of Spinocerebellar ataxia | 2016 |
52 | BEND | Bendable Bioplatform for Electrically stimulated Neuronal Differentiation | 2016 |
53 | Training4CRM | European Training Network for Cell-based Regenerative Medicine | 2016 |
54 | in3 | An integrated interdisciplinary approach to animal-free chemical and nanomaterial safety assessment | 2017 |
55 | CENSUS | Cell-Based Models for Neurodegeneration Study and Use in Screening | 2016 |
56 | RAPID | Chromatin dynamics resolved by rapid protein labeling and bioorthogonal capture | 2017 |
57 | FORMAT | FORMAT: a novel medium FOr Revolutionizing stem cell MAnufacturing Technologies | 2017 |
58 | Mini Brains | Cerebral organoids: human mini brains in a dish open up new possibilities for drug development in neurodegenerative and developmental diseases | 2017 |
59 | MiniBrain | Cerebral Organoids: Using stem cell derived 3D cultures to understand human brain development and neurological disorders | 2017 |
60 | CFED | Unravelling the mechanisms regulating cellular fitness during embryonic development | 2017 |
61 | REJUVENATION | Repair of Junctional Atrioventricular Conduction and Impulse Formation | 2017 |
62 | STOP-HF | STEM CELL MODELS TO UNRAVEL THE SUSCEPTIBILITY AND RESILIENCE TO DEVELOP HEART FAILURE | 2017 |
63 | Repro_organoid | Direct reprogramming of human astrocytes into functional neurons in cerebral organoids derived from genome edited hiPSCs | 2017 |
64 | MetEpiStem | Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells. | 2017 |
65 | ADAPTED | Alzheimers Disease Apolipoprotein Pathology for Treatment Elucidation and Development - Sofia ref.: 115975 | 2016 |
66 | miRStem | Reprogramming of elite B cells to induced hematopoietic stem cell with microRNAs and transcription factors | 2017 |
67 | MwHresEP | Multi-well High-resolution Electrophysiology Platform | 2017 |
68 | Cellphmed | Accurate cell signatures for the advancement of personalized medicine | 2017 |
69 | GEL-SYS | Smart HydroGEL SYStems – From Bioinspired Design to Soft Electronics and Machines | 2018 |
70 | CellKarma | Dissecting the regulatory logic of cell fate reprogramming through integrative and single cell genomics | 2018 |
71 | CELLNAIVETY | Deciphering the Molecular Foundations and Functional Competence of Alternative Human Naïve Pluripotent Stem Cells | 2017 |
72 | BONDS | Bilayered ON-Demand Scaffolds: On-Demand Delivery from induced Pluripotent Stem Cell Derived Scaffolds for Diabetic Foot Ulcers | 2017 |
73 | iNanoBIT | Integration of Nano- and Biotechnology for beta-cell and islet Transplantation | 2017 |
74 | SilkFUSION | Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research | 2017 |
75 | CISTEM | Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine | 2018 |
76 | New Chol | Development of New therapies against cholangiopathies. | 2017 |
77 | 5D Heart Patch | A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy | 2017 |
78 | MicroAdiPSChip | Micro-Fat Tissue on Chip | 2018 |
79 | iPS-ChOp-AF | Combining induced pluripotent stem cells, tissue engineering, optogenetic and chemogenetic concepts for the study and treatment of atrial fibrillation | 2018 |
80 | ELECTRO NEEDLE | In situ stem cell monitoring system based on conductive nanoneedle devices for tracking cell fates in invasive manner | 2018 |
81 | PREMEDiCARE | PREcision MEDicine with induced pluripotent stem cells for Cardiac Arrhythmias Risk Evaluation | 2018 |
82 | LEUKEYOLK | Uncovering the origin and mechanisms of Down syndrome-associated leukaemia through human induced pluripotent stem cell-derived haemopoiesis | 2019 |
83 | NeuroVU | NeuroVU: Real-time Sensing in Microfluidic Models of the Neurovascular Unit | 2018 |
84 | EpiTFeb | Deciphering the Transcriptional Logic of TFEB activation in cell identity and cancer | 2018 |
85 | NINTCORDEV | NIPBL and Integrator function and dysfunction in human cortical development | 2018 |
86 | NeuroRBP | Studying RNA-binding proteins involved in neural differentiation and degeneration | 2019 |
87 | MiniBRAIN | Investigating the pathogenic mechanisms underlying TUBB2B-related brain malformations using induced pluripotent stem cells and cerebral organoids. | 2019 |
88 | MAPSYNE | Miniaturized automated patch-clamp system combined with high-density microelectrode arrays for multi-scale functional mapping of neuronal networks | 2018 |
89 | Huntingtin hPSC | Unraveling huntingtin function in cortical and striatal human development | 2018 |
90 | CerebralHominoids | Evolutionary biology of human and great ape brain development in cerebral organoids | 2018 |
91 | PanINSULA | PanINSULA - The next first commercially sustainable and therapeutically effective beta cell therapy for diabetes | 2018 |
92 | NEVADA | Novel microengineered environments for mouse embryonic stem cell (mESC) differentiation towards cardiomyocytes | 2018 |
93 | HISTOID | A Human iPS Cell-Derived Artificial Skeletal Muscle for Regenerative Medicine, Disease Modelling and Drug Screening | 2018 |
94 | BIOCARD | Deep BIOmodeling of human CARDiogenesis | 2018 |
95 | TREAT-PD | Patient-specific treatment for Parkinson's disease using reprogrammed skin cells | 2018 |
96 | DiRECT | Directly reprogrammed renal cells for targeted medicine | 2019 |
97 | EASY-IPS | a rapid and efficient method for generation of iPSC | 2019 |
98 | TransTempoFold | A need for speed: mechanisms to coordinate protein synthesis and folding in metazoans | 2019 |
99 | SYNPATH | Regulation of synaptic development and plasticity by molecular pathways linked to human evolution | 2019 |
100 | iPSpine | Induced pluripotent stem cell-based therapy for spinal regeneration | 2019 |
101 | FutureTrophicFactors | Elucidating therapeutic effects and mode of action of future trophic factorsin ALS and Parkinson’s disease | 2019 |
102 | iHEAR | Gene therapy of inherited and acquired hearing loss | 2019 |
103 | NeuroDeRisk | Neurotoxicity De-Risking in Preclinical Drug Discovery | 2019 |
104 | SYNKIT | Synthetic Natural Killer Cells for Immunotherapy | 2020 |
105 | TaPPiNG-EPI | Targeting Purinergic Pathway in drug-resistant epilepsy using human Neurons and Glia. | 2019 |
106 | EmbryoPAINT | PAINTing the architecture of the totipotency gene network during early mammalian development | 2020 |
107 | iMIND | iPS-derived MIcroglia and Neuroinflammation in Dementia | 2020 |
108 | MiniEmbryoBlueprint | The mammalian body plan blueprint, an in vitro approach | 2019 |
109 | SiGNATURE | Selection of human iPSC-derived cardiomyocytes by sinGle cell geNe expression and pAtch clamp for a maTUre caRdiac modEl | 2020 |
110 | ReproXimera | Modelling in vivo lineage reprogramming of human astrocytes into induced neurons in the adult mouse brain | 2020 |
111 | CVD in RA | Mechanistic links between rheumatoid arthritis and cardiovascular complications: investigation on inflammation induced alterations in induced pluripotent stem cell-derived cardiomyocytes | 2020 |
112 | ANTHROPOID | Great ape organoids to reconstruct uniquely human development | 2019 |
113 | GHSO | Generation of human steroid-producing organoids: a new approach to treat adrenal insufficiency | 2019 |
114 | GERMINOID | Development of human primordial germ cells towards the onset of sperm and egg differentiation in a novel model culture system | 2019 |
115 | mAMBo | The role of ASCL1 and MYCN in human brain development | 2019 |
116 | STRELECOID | Stretchable mesh-electrodes interfacing human iPSC brain organoids | 2019 |
117 | COMMER-CELL | Commercialisation of neuronal cell co-cultures | 2019 |
118 | EBiSC2 | EBiSC2 – A sustainable European Bank for induced pluripotent Stem Cells | 2019 |
119 | RepDiff | Revealing novel molecular mechanisms linking DNA replication and cell fate decisions | 2020 |
120 | ActiTOX | Active organotypic models for nanoparticle toxicological screening | 2019 |
121 | SINERGIA | advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse | 2019 |
122 | NEUREKA | A smart, hybrid neural-computo device for drug discovery | 2019 |
123 | EmbryoMethFunc | Cell-Type Specific DNA Methylation Changes During Mammalian Development: Beyond Mapping | 2019 |
124 | PLANMod | Regulation of extreme plasticity in planarian stem cells by mRNA modifications | 2019 |
125 | SUMiDENTITY | Deconstructing the role of SUMO on chromatin in cell identity and tissue repair | 2020 |
126 | DyNAmecs | Early embryonic events, life-long consequences: DNA methylation dynamics in mammalian development | 2020 |
127 | OCTOBER | Control of cell identity in pluripotent and germline cells by OCT4 orchestration of chromatin binding and enhancer regulation | 2019 |
128 | SYNBIO.ECM | SYNBIO.ECM: Designer extracellular matrices to program healthy and diseased cardiac morphogenesis | 2020 |
129 | PLASTINET | Plasticity of the Pluripotency Network | 2020 |
130 | AutoCRAT | Automated Cellular Robot-Assisted Technologies for translation of discovery-led research in Osteoarthritis | 2020 |
131 | C-stemGMP | c-GMP compliance of C-stem, an IPSc based cell therapies production technology | 2019 |
132 | EpigeneticScars | Understanding DSB repair from pathway choice to long term effects and their consequences. | 2020 |
133 | BRAV3 | Computational biomechanics and bioengineering 3D printing to develop a personalized regenerative biological ventricular assist device to provide lasting functional support to damaged hearts | 2020 |
134 | NSC-Reconstruct | Novel Strategies for Cell-based Neural Reconstruction | 2020 |
135 | ISLET | Advancing Innovative Stem Cell-based Therapy for Diabetes in Europe | 2020 |
136 | RARE MAPS | Dynamic proteomic maps of stem cell-derived neurons as a mechanistic discovery pipeline for rare neurological disease | 2020 |
137 | FuncDis3D | Deconstructing gene regulation through functional dissection of the 3D genome | 2020 |
138 | xenCAKUT | CRISPR/Cas9 based kidney disease modeling to elucidate novel genetic drivers and therapeutic targets in X. tropicalis | 2020 |
139 | SmartHeart | SmartHeart, a 3D in vitro assay for improved assessment of cardiac drug efficacy and toxicity | 2020 |
140 | ACQUIRE | Assessing cardiac Contractility and Quantification of Underlying mechanisms In vitro via Response in Excitation-contraction coupling | 2020 |
141 | VirIVITES | ARBOVIRUS SKIN INFECTION MODELLING FOR MORE ACCURATE VIRAL PATHOGENESIS | 2020 |