DeepMiR
Innovative testing of microRNA from liquid biopsies using bistable molecular circuits
Total Cost €
0EC-Contrib. €
0Partnership
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0DeepMiR project word cloud
Explore the words cloud of the DeepMiR project. It provides you a very rough idea of what is the project "DeepMiR" about.
Project "DeepMiR" data sheet
The following table provides information about the project.
| Coordinator |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Organization address contact info |
| Coordinator Country | France [FR] |
| Total cost | 149˙852 € |
| EC max contribution | 149˙852 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2017-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-12-01 to 2019-05-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | FR (PARIS) | coordinator | 149˙852.00 |
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Project objective
We are designing molecular networks - based on DNA programing- to detect extremely dilute molecular signals and robustly separate them from background noise. This could have relevant applications in the field of molecular diagnostics, in particular in the area of ultra-sensitive testing of nucleic acids from liquid biopsy for example for the detection of circulating microRNA. MicroRNA are difficult targets for standard ultra sensitive techniques such as quantitative PCR, but, because of their presence in the blood stream, they also represent an emerging class of important biomarkers for a wide range of diseases, including cancer. This project will allow us to put together a proof of principle, based of clinically relevant targets and sample, that will clearly demonstrate the benefit of our approach for the molecular diagnostic of microRNA, in terms of sensibility, multiplexing, robustness, modularity and simplicity in sample preparation.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Guillaume Gines, Roberta Menezes, Kaori Nara, Anne-Sophie Kirstetter, Valérie Taly, Yannick Rondelez Isothermal digital detection of microRNA using background-free molecular circuit published pages: , ISSN: , DOI: 10.1101/701276 |
BioArXiv | 2020-01-30 |
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The information about "DEEPMIR" are provided by the European Opendata Portal: CORDIS opendata.