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MicroBone SIGNED

Novel 3D platforms to engineer bone microtissues for in vitro disease models

Total Cost €

EC-Contrib. €

Partnership

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MicroBone project word cloud

Explore the words cloud of the MicroBone project. It provides you a very rough idea of what is the project "MicroBone" about.

predictive 3d bone cancer precision elderly effect disease adolescents mechanisms tool osteosarcoma devastating children biological tumour candidates vitro models urgent treatments resistant anticancer microbone mainly therapy discovery environment personalized recapitulate natural drug therapies rare spherical

Project "MicroBone" data sheet

The following table provides information about the project.

Coordinator	UNIVERSIDADE DE AVEIRO Organization address address: CAMPUS UNIVERSITÁRIO DE SANTIAGO city: AVEIRO postcode: 3810-193 website: www.ua.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Portugal [PT]
Total cost	150˙000 €
EC max contribution	150˙000 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2017-PoC
Funding Scheme	ERC-POC
Starting year	2018
Duration (year-month-day)	from 2018-03-01 to 2019-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSIDADE DE AVEIRO UNIVERSIDADE DE AVEIRO Organization address address: CAMPUS UNIVERSITÁRIO DE SANTIAGO city: AVEIRO postcode: 3810-193 website: www.ua.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (AVEIRO)	coordinator	150˙000.00

Map

Project objective

Osteosarcoma is a rare but devastating bone tumour that mainly affects children, adolescents and elderly. This type of tumour is very resistant to therapy, being thus urgent to find new effective treatments. In vitro tumour models can recapitulate many aspects of the natural tumour environment, and could be used to improve the predictive value of the effect of anticancer drug candidates. The aim of MicroBone is the development of biological relevant spherical-based 3D disease models that could be used as an enabling tool for personalized and precision drug discovery, increasing our understanding of the mechanisms behind bone cancer and testing new drug-based therapies.

Publications

List of publications.
year	authors and title	journal	last update
2018	Sara C. Santos, Catarina A. CustÃ³dio, JoÃ£o F. Mano Photopolymerizable Platelet Lysate Hydrogels for Customizable 3D Cell Culture Platforms published pages: 1800849, ISSN: 2192-2640, DOI: 10.1002/adhm.201800849	Advanced Healthcare Materials 7/23	2020-04-11
2019	CÃ¡tia F. Monteiro, Catarina A. CustÃ³dio, JoÃ£o F. Mano Three-Dimensional Osteosarcoma Models for Advancing Drug Discovery and Development published pages: 1800108, ISSN: 2366-3987, DOI: 10.1002/adtp.201800108	Advanced Therapeutics 2/3	2020-04-11

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The information about "MICROBONE" are provided by the European Opendata Portal: CORDIS opendata.