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EpiSyStem SIGNED

Epigenetics and System Biology of Stem cells and Reprogramming

Total Cost €

EC-Contrib. €

Partnership

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EpiSyStem project word cloud

Explore the words cloud of the EpiSyStem project. It provides you a very rough idea of what is the project "EpiSyStem" about.

community expanded view deep training pluripotency diseases renowned acclaimed combines granted life cells functional board environment basic epigenomics workshops chromatin biology profound world biological technologies 14 international scientific communicate embryo breakthroughs exchange erc phd advisory leadership embryos coupled global conferences dramatically cell trained supervised mesh human exposed contacts fundamental network single experts programs episystem differentiation holistic forefront genome stem students regulation controls population neurological outstanding epigenetic reprogramming transcription scientists professional meetings create questions public developmental comprised regulatory latest enjoy epigenetics industrial multidisciplinary bioinformatics

Project "EpiSyStem" data sheet

The following table provides information about the project.

Coordinator	THE HEBREW UNIVERSITY OF JERUSALEM Organization address address: EDMOND J SAFRA CAMPUS GIVAT RAM city: JERUSALEM postcode: 91904 website: www.huji.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Israel [IL]
Total cost	3˙598˙191 €
EC max contribution	3˙598˙191 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2017
Funding Scheme	MSCA-ITN-ETN
Starting year	2018
Duration (year-month-day)	from 2018-03-01 to 2022-02-28

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE HEBREW UNIVERSITY OF JERUSALEM THE HEBREW UNIVERSITY OF JERUSALEM Organization address address: EDMOND J SAFRA CAMPUS GIVAT RAM city: JERUSALEM postcode: 91904 website: www.huji.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (JERUSALEM)	coordinator	780˙901.00
2	INSTITUT CURIE INSTITUT CURIE Organization address address: rue d'Ulm 26 city: PARIS postcode: 75231 website: www.curie.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	525˙751.00
3	UNIVERSITA DEGLI STUDI DI MILANO UNIVERSITA DEGLI STUDI DI MILANO Organization address address: Via Festa Del Perdono 7 city: MILANO postcode: 20122 website: www.unimi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	516˙122.00
4	KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW Organization address address: KLOVENIERSBURGWAL 29 HET TRIPPENHUIS city: AMSTERDAM postcode: 1011 JV website: www.knaw.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	510˙748.00
5	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Organization address address: INGOLSTADTER LANDSTRASSE 1 city: NEUHERBERG postcode: 85764 website: www.helmholtz-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (NEUHERBERG)	participant	498˙432.00
6	KADIMASTEM LTD KADIMASTEM LTD Organization address address: PINCHAS SAPIR STR 7 WEIZMANN SCIENCE PARK city: NES ZIONA postcode: 74140 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (NES ZIONA)	participant	260˙300.00
7	STICHTING KATHOLIEKE UNIVERSITEIT STICHTING KATHOLIEKE UNIVERSITEIT Organization address address: GEERT GROOTEPLEIN NOORD 9 city: NIJMEGEN postcode: 6525 EZ website: www.radboudumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (NIJMEGEN)	participant	255˙374.00
8	DIAGENODE DIAGENODE Organization address address: RUE DU BOIS SAINT JEAN 3 LIEGE PARK SCIENCE city: SERAING postcode: 4102 website: www.diagenode.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (SERAING)	participant	250˙560.00

Map

Project objective

Chromatin is the basic regulatory unit of life, and as such it controls developmental and functional states of all cells, including pluripotency. In recent years methods to study chromatin and transcription have dramatically improved and expanded to genome-wide global approaches on the one hand, and single cell biology on the other, allowing systems-level understanding of epigenetic regulation of stem cells, reprogramming and development. The Epigenetics and Systems Biology of Stem Cells and Reprogramming Network (EpiSyStem) is comprised of 8 world renowned, ERC-granted researchers, 2 professional leading industrial partners and supported by 3 partner organizations and 3 international world acclaimed scientists as an advisory board, to provide a unique training environment. EpiSyStem combines chromatin biology in stem cells, early embryos and reprogramming, including the modelling of human neurological, chromatin-related diseases with bioinformatics, epigenetics/epigenomics, and systems biology at the population and single cell / single embryo level. This multidisciplinary approach will enable profound training and deep, systems-level understanding of chromatin biology and epigenetic regulation of stem cells, differentiation and reprogramming, with a strong support by industrial partners. The objectives of EpiSyStem is to create a European mesh in which 14 outstanding PhD students will be trained in fundamental questions of biological research, be exposed to the latest technologies and breakthroughs, supervised by leading experts with international contacts - with the aim to facilitate their path to future leadership with holistic view, coupled with the forefront of the current epigenetic research in the field. They will enjoy exchange programs, workshops on emerging topics in stem cell epigenetics and bioinformatics, international conferences and meetings, and will communicate their findings to the scientific community as well as the general public.

Publications

List of publications.
year	authors and title	journal	last update
2019	Matteo Zanella, Alessandro Vitriolo, Alejandro Andirko, Pedro Tiago Martins, Stefanie Sturm, Thomas Oâ€™Rourke, Magdalena Laugsch, Natascia Malerba, Adrianos Skaros, Sebastiano Trattaro, Pierre-Luc Germain, Marija Mihailovic, Giuseppe Merla, Alvaro Rada-Iglesias, Cedric Boeckx, Giuseppe Testa Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication published pages: eaaw7908, ISSN: 2375-2548, DOI: 10.1126/sciadv.aaw7908	Science Advances 5/12	2020-04-11

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The information about "EPISYSTEM" are provided by the European Opendata Portal: CORDIS opendata.