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BRAIN SIGNED

Bacterial regulation of Apis neurophysiology

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 BRAIN project word cloud

Explore the words cloud of the BRAIN project. It provides you a very rough idea of what is the project "BRAIN" about.

microbial    brain    harvest    exponentially    gut    microscopy    bees    groups    symbiont    traits    insects    honeybee    ecology    biologists    neurotranscriptomics    ambitions    elusive    isotope    understand    inter    physiological    predict    evolutionary    manipulation    symbioses    experimental    transcriptomics    function    health    training    mellifera    little    symbiosis    he    metabolic    axis    fish    realize    gene    tracking    behavioural    domesticated    conceptual    metabolites    microbiome    synergistic    transfer    bioinformatics    neurophysiology    published    social    easily    secure    map    molecular    genome    investigations    disciplinary    host    grown    extended    mammalian    labelling    data    species    modifications    cultured    organization    sequencing    microbiota    animal    apis    characterization    insemination    hosts    neurological    interactions    none    economic    benefits    phenotypes    think    previously    expression    regions    theory    area    microbiology    bacteria    ants    food    feasible    tangible    primary    symbionts    considerable    bacterial    diversity    ecologist    microbes   

Project "BRAIN" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE DE LAUSANNE 

Organization address
address: Quartier Unil-Centre Bâtiment Unicentre
city: LAUSANNE
postcode: 1015
website: www.unil.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-07-01   to  2020-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE DE LAUSANNE CH (LAUSANNE) coordinator 175˙419.00

Map

 Project objective

Gut microbes are known to affect the neurophysiology of their hosts and genome sequencing now easily allows metabolic characterization of elusive microbial diversity that cannot be cultured. While investigations on the neurological and behavioural consequences of mammalian gut symbionts have grown exponentially in recent years, little is known about the ‘gut microbiota–brain axis’ in insects of major economic interest. The applicant is a molecular evolutionary ecologist who previously used gene expression data to predict physiological modifications in the honeybee after insemination and published a comparative analysis of bacterial symbionts across ants. He now aims to realize an inter-disciplinary program to map the neurological and behavioural extended phenotypes of gut symbionts in bees. Through experimental approaches of microbiome manipulation, neurotranscriptomics, behavioural-tracking, FISH, and isotope-labelling of bacterial metabolites, the project seeks to understand: (i) the extent to which Apis mellifera gut symbionts affect host brain function by identifying the specific bacteria, their metabolic products, and the brain regions involved in host-symbiont interactions, and (ii) assess whether these processes affect behavioural traits relevant for the social organization of bees. None of these objectives have been addressed before and achieving them has high potential to change the way in which biologists think about bacterial symbioses and animal behaviour. The project includes training-through-research for the applicant in microbiology, behavioural ecology, microscopy and bioinformatics, and considerable knowledge transfer in transcriptomics and conceptual symbiosis theory from the applicant to the host groups. Although challenging in its ambitions, the project is synergistic and feasible, and will allow the European Research Area to harvest tangible benefits to improve the health of a domesticated species of primary importance to secure food production.

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The information about "BRAIN" are provided by the European Opendata Portal: CORDIS opendata.

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