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EARLYRIDERS SIGNED

Tracking the temporal and geographic origins of modern domestic horses

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 EARLYRIDERS project word cloud

Explore the words cloud of the EARLYRIDERS project. It provides you a very rough idea of what is the project "EARLYRIDERS" about.

diseases    horse    interconnected    horses    disease    scalable    serious    researcher    content    locus    passively    techniques    source    wave    absent    endogenous    genome    transmitted    gene    full    age    originating    point    pathogens    transport    contagious    vectors    shows    plague    fleas    riding    found    domestic    agriculture    forged    strains    larger    dna    enrichment    domestication    hundreds    archaeological    ancient    riders    vector    gap    modern    load    centers    earliest    form    humans    sequencing    hyrad    300    earlyriders    either    subjected    spread    sequence    rapid    moderate    trade    societies    interplay    despite    epizootic    ancestors    history    thousands    question    concurrent    accounted    bronze    turning    pathogen    revolutionizing    warfare    transmission    geographic    transfer    unknown    allowed    epidemiology    human    haunted    appears    dating    poorly    instance    temporal    loci    populations    samples   

Project "EARLYRIDERS" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE PAUL SABATIER TOULOUSE III 

Organization address
address: ROUTE DE NARBONNE 118
city: TOULOUSE CEDEX 9
postcode: 31062
website: www.ups-tlse.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 173˙076 €
 EC max contribution 173˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE PAUL SABATIER TOULOUSE III FR (TOULOUSE CEDEX 9) coordinator 173˙076.00

Map

 Project objective

The goal of the EARLYRIDERS project is to identify the geographic and temporal locus of modern horse domestication. It also focuses on the interplay between domestication and the increase of pathogen load in horses, and the role of epizootic transfer of human pathogens, especially plague. Horse domestication represents a turning point in human history, revolutionizing transport, trade, warfare, agriculture, and allowing humans to form larger, interconnected societies. Despite its importance for human history, this process remains poorly understood. Recent genome sequencing shows that the earliest archaeological remains of domestic horses are not the ancestors of modern domestic horses and that another, still unknown, wave of domestication forged the modern horse during the Early Bronze Age. Horse riding also allowed a rapid spread of diseases. For instance, the plague, that regularly haunted human populations in history, has been already commonly found in human remains dating to the Early Bronze Age. As the gene essential for the transmission through fleas was absent in these ancient strains, the plague might have been transmitted through other, still unknown vectors. This represents a serious gap in understanding of the early epidemiology of this important disease. As the spread of plague appears to be concurrent to horse domestication, the question remains whether the horse accounted for its spread, either as a vector or passively, by contagious riders. We aim at identifying the source of the second domestication wave and pathogen load in ancient horse populations by sequencing 300 samples originating from all potential centers of domestication. Full genome sequencing is not possible due to low endogenous DNA content, therefore the samples will be subjected to sequence enrichment techniques, including the novel hyRAD method developed by the experienced researcher, scalable to thousands of loci in hundreds of samples at moderate cost.

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