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EPICLINES SIGNED

Elucidating the causes and consequences of the global pattern of epigenetic variation in Arabidopsis thaliana

Total Cost €

EC-Contrib. €

Partnership

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EPICLINES project word cloud

Explore the words cloud of the EPICLINES project. It provides you a very rough idea of what is the project "EPICLINES" about.

dna epigenetics genetic global cress thaliana epigenetic mechanism fascinate trait model paradoxically clear inherited arabidopsis suggests lamarckian basis blurs question suggest natural thale methylation variables levels showed appears traits nature plant variation correlation somewhat experimentally inheritance climate acquired continues nurture revealed line elucidate notion ultimate experiments pattern

Project "EPICLINES" data sheet

The following table provides information about the project.

Coordinator	GREGOR MENDEL INSTITUT FUR MOLEKULARE PFLANZENBIOLOGIE GMBH Organization address address: DR BOHR GASSE 3 city: WIEN postcode: 1030 website: www.gmi.oeaw.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Austria [AT]
Total cost	2˙498˙468 €
EC max contribution	2˙498˙468 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2017-ADG
Funding Scheme	ERC-ADG
Starting year	2018
Duration (year-month-day)	from 2018-06-01 to 2023-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	GREGOR MENDEL INSTITUT FUR MOLEKULARE PFLANZENBIOLOGIE GMBH GREGOR MENDEL INSTITUT FUR MOLEKULARE PFLANZENBIOLOGIE GMBH Organization address address: DR BOHR GASSE 3 city: WIEN postcode: 1030 website: www.gmi.oeaw.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	coordinator	2˙498˙468.00

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Project objective

Epigenetics continues to fascinate, especially the notion that it blurs the line between “nature and nurture” and could make Lamarckian adaptation via the inheritance of acquired characteristics possible. That this is in principle possible is clear: in the model plant Arabidopsis thaliana (Thale cress), experimentally induced DNA methylation variation can be inherited and affect important traits. The question is whether this is important in nature. Recent studies of A. thaliana have revealed a pattern of correlation between levels of methylation and climate variables that strongly suggests that methylation is important in adaptation. However, somewhat paradoxically, the experiments also showed that much of the variation for this epigenetic trait appears to have a genetic rather than an epigenetic basis. This suggest that epigenetics may indeed be important for adaptation, but as part of a genetic mechanism that is currently not understood. The goal of this project is to determine whether the global pattern of methylation has a genetic or an epigenetic basis, and to use this information to elucidate the ultimate basis for the global pattern of variation: natural selection.

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The information about "EPICLINES" are provided by the European Opendata Portal: CORDIS opendata.