SOLUPORE SIGNED

Project "SOLUPORE" data sheet

The following table provides information about the project.

 Partnership

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Map

 Project objective

There is encouraging news for cancer patients, a new treatment, cell immunotherapy, has been delivering spectacular clinical results and is a game changer because it is an entirely new way of treating cancer. Cancer immunotherapy, in which a patient’s own immune cells are ‘armed’ by cell engineering to target and kill cancer cells, gives levels of complete response in patients. The first cell immunotherapy drug was approved in August 2017 at a price of $475,000 per treatment. To bring these life-changing treatments to patients and relieve the European and global healthcare burden they must become available at affordable costs. The one thing worse than failure is unaffordable success and the challenge with these treatments is the complex and high-cost of manufacturing. Current cell engineering methods are very expensive to manufacture. Avectas has developed Solupore, a cell engineering technology, which delivers cargo to cells and plays a critical role in the manufacturing process. The technology works by temporarily making the cell membrane permeable and allowing cargo into the cell. Crucially, cell health and functionality are preserved while there is a significant improvement on the process time and costs. Avectas has demonstrated that the pilot system can successfully deliver clinically relevant cargo to T cells. During this project, Avectas will scale and align Solupore to regulatory compliance enabling us to commercialise it. The emerging and fast-growing cell immunotherapy market is set to be worth $20bn in 2020, with cell manufacturing representing $5bn. Commercialisation of Solupore will take 1% of the €5bn market share by 2024 and will generate global revenues for Avectas, building value for the company and creating highly skilled jobs which will result in a high-value, knowledge-based EU company. There will be substantial European and global socio-economic impact on cancer patients living longer, better quality lives.