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ADAPTOS SIGNED

ADAPTOS - Changing the way bone voids are treated

Total Cost €

EC-Contrib. €

Partnership

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ADAPTOS project word cloud

Explore the words cloud of the ADAPTOS project. It provides you a very rough idea of what is the project "ADAPTOS" about.

quality blood clinical source causing clinics regeneration first human minor off meet proof 17 revenue autografts tissue collaborating freedom estimate offers burden 2023 caused craniomaxillofacial orthopaedic sme team 50 autografting plentiful adaptos transplant transfusions 35 country disability surgeons thanks penetrate complications substitute resilient reference harvests suitable employees graft allograft hospitals trade spinal operations dominant valued gives founding mimics enter there million animals fusion bank sourcing cross painful bone operate market onboarding patient annually initially options performed regard disciplinary drawbacks synthetic risky line trial employing animal validated world billion trailing bioactive markets autograft

Project "ADAPTOS" data sheet

The following table provides information about the project.

Coordinator	BIOMENDEX OY Organization address address: TAKAMAANTIE 4 A 4 city: PIRKKALA postcode: 33960 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Finland [FI]
Total cost	3˙212˙500 €
EC max contribution	2˙248˙750 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-2
Funding Scheme	SME-2
Starting year	2019
Duration (year-month-day)	from 2019-10-01 to 2021-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	BIOMENDEX OY BIOMENDEX OY Organization address address: TAKAMAANTIE 4 A 4 city: PIRKKALA postcode: 33960 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (PIRKKALA)	coordinator	2˙248˙750.00

Map

Project objective

There are 4 million operations performed annually that require a bone graft. This makes bone the second most common tissue transplant in the world, trailing only blood transfusions.

There are three options where to source the bone today. Directly from the patient (autograft), from a bone bank (allograft) or using a substitute. The dominant method today is autografting. This is because human’s own bone is easy to use and offers plentiful regeneration properties.

However, autografting is painful and risky, causing complications in 50% of harvests. This has caused orthopaedic surgeons to regard autografting as a trade-off between sourcing a suitable bone at the cost of a minor disability for the patient. This is where Adaptos comes in. Adaptos is the only bone graft substitute that mimics bone by being resilient and bioactive. Adaptos gives surgeons the freedom to operate, as they were using autografts, without the drawbacks.

Today, Adaptos is already in use across 9 animal clinics. By collaborating with numerous surgeons, we have validated our technology as the best bone graft substitute on the market.

We will initially enter the synthetic bone graft substitute market valued at €2.1 billion. We aim to penetrate the less complex markets first (animals, craniomaxillofacial & orthopaedic applications). Through these applications, we will build reference cases to meet the high burden-of-proof required to enter the most complex applications (e.g. Spinal fusion).

Our cross-disciplinary founding team will use the SME-project to scale up Adaptos’ production line, build reference cases across 3 hospitals via a multi-country clinical trial and improve our onboarding of orthopaedic surgeons in the process.

Thanks to the SME-project, we estimate that we will reach €17 million in revenue by 2023 while employing 35 high-quality employees.

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The information about "ADAPTOS" are provided by the European Opendata Portal: CORDIS opendata.