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ORIGIN SIGNED

Optical Fibre Dose Imaging for Adaptive Brachytherapy

Total Cost €

EC-Contrib. €

Partnership

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ORIGIN project word cloud

Explore the words cloud of the ORIGIN project. It provides you a very rough idea of what is the project "ORIGIN" about.

volume mgy treatment risk radiation interrogation imaging gy dose manufacturing cancer efficiency whilst error confirm hdr sensors snr personalised sensor signal outset 55 2500 ratio source consideration monitoring resolution alongside point mapping fibre counts fabrication organs enabled prescribed origin plans repeatable 150 enhanced prevention brachytherapy 1s tumour 3mm 16 collection clinical manufacturability led noise 5 patient sensitivity rate fore outcomes 50 photonics improvement errors spatial bt dosimeters acquisition limits data oars 5mm ldr therapy acceptable diagnostics time 5s optical oriented establishes reduce planning location adaptive localisation

Project "ORIGIN" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY OF LIMERICK Organization address address: NATIONAL TECHNOLOGICAL PARK, PLASSEY city: LIMERICK postcode: - website: www.ul.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Total cost	4˙819˙920 €
EC max contribution	4˙819˙920 € (100%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2019-2
Funding Scheme	RIA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2022-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY OF LIMERICK UNIVERSITY OF LIMERICK Organization address address: NATIONAL TECHNOLOGICAL PARK, PLASSEY city: LIMERICK postcode: - website: www.ul.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (LIMERICK)	coordinator	913˙380.00
2	VRIJE UNIVERSITEIT BRUSSEL VRIJE UNIVERSITEIT BRUSSEL Organization address address: PLEINLAAN 2 city: BRUSSEL postcode: 1050 website: www.vub.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUSSEL)	participant	741˙528.00
3	DOSEVUE DOSEVUE Organization address address: Agoralaan Abis city: Diepenbeek postcode: 3590 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (Diepenbeek)	participant	705˙250.00
4	THE QUEEN'S UNIVERSITY OF BELFAST THE QUEEN'S UNIVERSITY OF BELFAST Organization address address: UNIVERSITY ROAD LANYON BUILDING city: BELFAST postcode: BT7 1NN website: www.qub.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BELFAST)	participant	688˙342.00
5	ECKERT & ZIEGLER BEBIG GMBH ECKERT & ZIEGLER BEBIG GMBH Organization address address: ROBERT-ROSSLE STRASSE 10 city: BERLIN postcode: 13125 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	590˙812.00
6	UNIVERSITA DEGLI STUDI DELL'INSUBRIA UNIVERSITA DEGLI STUDI DELL'INSUBRIA Organization address address: VIA RAVASI 2 city: VARESE postcode: 21100 website: www.uninsubria.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (VARESE)	participant	462˙150.00
7	GALWAY CLINIC DOUGHISKA LIMITED GALWAY CLINIC DOUGHISKA LIMITED Organization address address: DOUGHISKA city: GALWAY postcode: H91 HHTO website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (GALWAY)	participant	372˙456.00
8	CENTRE ANTOINE LACASSAGNE CENTRE ANTOINE LACASSAGNE Organization address address: AVENUE VALOMBROSE 33 city: NICE CEDEX postcode: 6054 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (NICE CEDEX)	participant	346˙000.00

Map

Project objective

ORIGIN aims to deliver more effective, photonics-enabled, brachytherapy for cancer treatment through advanced real-time radiation dose imaging and source localisation. This will be achieved by the development of a new optical fibre based sensor system to support diagnostics-driven therapy through enhanced adaptive brachytherapy. A 16-point optical fibre sensors system will be developed, for Low Dose Rate (LDR) and High Dose Rate (HDR) Brachytherapy, with sensitivity of 150 counts/Gy for LDR- and 2500 counts/mGy for HDR- BT alongside a dedicated data acquisition system providing a dose mapping system with a spatial resolution of 0.5mm (HDR) and 3mm (LDR) and time resolution of 0.1s (HDR) and 0.5s (LDR), with 5% uncertainty. This is a 50% improvement in uncertainty over existing systems. Further interrogation of the optical signal will provide real-time monitoring of the radiation source location during treatment. The ORIGIN system will be integrated into existing clinical brachytherapy treatment planning and delivery systems to confirm that the dose prescribed to the tumour is achieved, whilst ensuring the dose to organs at risk (OARs) is within acceptable limits. This will provide for optimised dose-led, patient-oriented, personalised treatment plans leading to improved patient outcomes and prevention of treatment errors, with the potential to reduce the overall risk of treatment error by 55%. The optical fibre radiation dosimeters will be further optimised for improved optical signal collection efficiency, higher signal-to-noise ratio (SNR) and repeatable high volume fabrication. Taking manufacturability into consideration from the outset will ensure that ORIGIN establishes Europe at the fore of brachytherapy system development and photonics manufacturing.

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The information about "ORIGIN" are provided by the European Opendata Portal: CORDIS opendata.