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RECOGNISED SIGNED

Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia

Total Cost €

EC-Contrib. €

Partnership

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RECOGNISED project word cloud

Explore the words cloud of the RECOGNISED project. It provides you a very rough idea of what is the project "RECOGNISED" about.

strategies decline alzheimer multidisciplinary impairment mounting population severity 15 belonging collected brain neurodegeneration eatris smes evaluation basis healthcare burden phenotypic disease prevalence tool retina prestigious clinical individuals patients diabetic biobanks overarching recognised tests personalized biomarkers stratify appropriately serum cognitive idf retinal exploited societal valuable dramatic recommendations structural cohorts families previously consist pathogenesis functional data either reported huge innovative dementia tissue therapeutic diabetes leaders medicine complication mechanisms molecular registries risk co morbid will ontogenically microvascular economic indicators dr reduce ultimately phenotypes guide t2d

Project "RECOGNISED" data sheet

The following table provides information about the project.

Coordinator	FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA Organization address address: PASSEIG VALL D HEBRON 119-129 EDIFICIO DE RECERCA city: BARCELONA postcode: 8035 website: http://www.vhir.org/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Total cost	5˙998˙272 €
EC max contribution	5˙998˙272 € (100%)
Programme	1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
Code Call	H2020-SC1-2019-Two-Stage-RTD
Funding Scheme	RIA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2023-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA Organization address address: PASSEIG VALL D HEBRON 119-129 EDIFICIO DE RECERCA city: BARCELONA postcode: 8035 website: http://www.vhir.org/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	coordinator	950˙410.00
2	AIBILI ASSOCIACAO PARA INVESTIGACAO BIOMEDICA E INNOVACAO EM LUZ E IMAGEM AIBILI ASSOCIACAO PARA INVESTIGACAO BIOMEDICA E INNOVACAO EM LUZ E IMAGEM Organization address address: Azinhaga de Santa Comba, Celas city: COIMBRA postcode: 3000 548 website: www.aibili.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (COIMBRA)	participant	822˙760.00
3	THE QUEEN'S UNIVERSITY OF BELFAST THE QUEEN'S UNIVERSITY OF BELFAST Organization address address: UNIVERSITY ROAD LANYON BUILDING city: BELFAST postcode: BT7 1NN website: www.qub.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BELFAST)	participant	763˙001.00
4	OSPEDALE SAN RAFFAELE SRL OSPEDALE SAN RAFFAELE SRL Organization address address: VIA OLGETTINA 60 city: MILANO postcode: 20132 website: www.hsr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	589˙000.00
5	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	450˙000.00
6	UNIVERSITAIR MEDISCH CENTRUM UTRECHT UNIVERSITAIR MEDISCH CENTRUM UTRECHT Organization address address: HEIDELBERGLAAN 100 city: UTRECHT postcode: 3584 CX website: www.umcutrecht.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (UTRECHT)	participant	297˙207.00
7	SYDDANSK UNIVERSITET SYDDANSK UNIVERSITET Organization address address: CAMPUSVEJ 55 city: ODENSE M postcode: 5230 website: www.sdu.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (ODENSE M)	participant	250˙000.00
8	UNIVERSITA DEGLI STUDI DI MILANO UNIVERSITA DEGLI STUDI DI MILANO Organization address address: Via Festa Del Perdono 7 city: MILANO postcode: 20122 website: www.unimi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	250˙000.00
9	UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA Organization address address: VIA CRACOVIA 50 city: ROMA postcode: 133 website: www.uniroma2.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	248˙250.00
10	UNIVERSIDAD DE CADIZ UNIVERSIDAD DE CADIZ Organization address address: CENTRO CULTURAL REINA SOFIA PASEO CARLOS III N9 city: CADIZ postcode: 11003 website: www.uca.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (CADIZ)	participant	229˙672.00
11	INSTITUT CATALA DE LA SALUT INSTITUT CATALA DE LA SALUT Organization address address: GRAN VIA DE LES CORTS CATALANES 587 city: BARCELONA postcode: 8007 website: http://www.gencat.cat/ics/germanstrias/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	196˙021.00
12	AZIENDA OSPEDALIERO-UNIVERSITARIA MAGGIORE DELLA CARITA NOVARA AZIENDA OSPEDALIERO-UNIVERSITARIA MAGGIORE DELLA CARITA NOVARA Organization address address: CORSO MAZZINI 18 city: NOVARA postcode: 28100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (NOVARA)	participant	183˙750.00
13	FUNDACIO ASSISTENCIAL DE MUTUA DE TERRASSA FUNDACIO PRIVADA CATALANA FUNDACIO ASSISTENCIAL DE MUTUA DE TERRASSA FUNDACIO PRIVADA CATALANA Organization address address: C/ SANT ANTONI 32 city: TERRASSA postcode: 8221 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (TERRASSA)	participant	180˙950.00
14	KLINICKI CENTAR CRNE GORE PODGORICA KLINICKI CENTAR CRNE GORE PODGORICA Organization address address: LJUBLJANSKA BB city: PODGORICA postcode: 81000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ME (PODGORICA)	participant	127˙500.00
15	EATRIS ERIC EATRIS ERIC Organization address address: DE BOELELAAN 1118 city: AMSTERDAM postcode: 1081 HZ website: www.eatris.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	104˙000.00
16	GENESIS BIOMED GENESIS BIOMED Organization address address: BALDIRI REIXAC 4 city: BARCELONA postcode: 8028 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	100˙875.00
17	ANAXOMICS BIOTECH SL ANAXOMICS BIOTECH SL Organization address address: CALLE DIPUTACIO 237, P 1 PTA 1 city: BARCELONA postcode: 8007 website: www.anaxomics.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	95˙000.00
18	JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA Organization address address: CETINJSKA 2 city: PODGORICA postcode: 81000 website: www.ucg.ac.me contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ME (PODGORICA)	participant	54˙875.00
19	ALZHEIMER EUROPE ALZHEIMER EUROPE Organization address address: RUE DICKS 14 city: LUXEMBOURG postcode: 1417 website: www.alzheimer-europe.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LU (LUXEMBOURG)	participant	35˙000.00
20	FEDERATION INTERNATIONALE DU DIABETE REGION EUROPE AISBL FEDERATION INTERNATIONALE DU DIABETE REGION EUROPE AISBL Organization address address: CHAUSSEE DE LA HULPE 166 BLOC C city: BRUXELLES postcode: 1170 website: http://www.idf-europe.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	participant	35˙000.00
21	OXURION OXURION Organization address address: GASTON GEENSLAAN 1 city: LEUVEN postcode: 3001 website: www.thrombogenics.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	participant	35˙000.00

Map

Project objective

In recent years there is mounting evidence that type 2 diabetes (T2D) is associated with cognitive impairment and dementia, which can be considered as a “new” long-term diabetic co-morbid complication with dramatic consequences for patients and their families and a significant impact for healthcare systems. At present there are no reported phenotypic indicators or reliable tests to identify T2D patients at risk of developing dementia. Since the retina is ontogenically a brain-derived tissue, we propose that the evaluation of retinal parameters related to either neurodegeneration or microvascular disease will be robust and valuable biomarkers to identify those T2D patients at higher risk of developing cognitive impairment and dementia. On this basis the overarching aims of the project are: 1) To investigate the common mechanisms involved in the pathogenesis of DR and cognitive impairment in the T2D. 2) To use the retina as a tool to identifying individuals with T2D at a higher risk of developing cognitive decline or dementia. Our multidisciplinary consortium (RECOGNISED) consist of top research leaders in the field belonging to 15 prestigious institutions as well as EATRIS, IDF-Europe and Alzheimer Europe and 3 SMEs. RECOGNISED will apply innovative approaches to identify the molecular mechanisms involved in the high prevalence of cognitive impairment and dementia in T2D population and will use this knowledge to characterize clinical phenotypes (personalized medicine) based on retinal functional and structural characteristics and serum biomarkers in order to stratify the risk and severity of cognitive decline. Previously collected data from registries, cohorts and biobanks will be appropriately exploited and robust new data will be generated that will guide clinical recommendations and open up new therapeutic strategies. Ultimately, RECOGNISED project will help to reduce the huge societal and economic burden associated with diabetes-related cognitive impairment.

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The information about "RECOGNISED" are provided by the European Opendata Portal: CORDIS opendata.