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MEISi SIGNED

Druggable Small Molecule Inhibitor of MEIS Proteins

Total Cost €

EC-Contrib. €

Partnership

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MEISi project word cloud

Explore the words cloud of the MEISi project. It provides you a very rough idea of what is the project "MEISi" about.

regulations performing countries entry sizes mechanisms cvds owing published strategies deep never noncommunicable nature modulate startup pct usd active discovery deadliest 3b massive hoxa9 tackling benchmarking meinox deaths ncds prestigious co metabolism innovative pending markets strategy pharmaceutically molecule tools family ingredients conduct share druggable customers class ending meisi significance biology diseases inhibits proteins segment selective efforts 2018 benefit protein cancer plays risk tgif2 drug journals molecular critical oncology accounting cell diabetes substance channels meis 10m tech 71 national market pbx proper indicate stem patented 44 motivates competitive global therapeutics first inhibitors commercialization plan cardiovascular nearly validated company feasibility small globally 29

Project "MEISi" data sheet

The following table provides information about the project.

Coordinator	MEINOX ILAC TEKNOLOJILERI AS Organization address address: RESITPASA MAH. KATAR CAD. TEKNOKENT ARI 1 NO: 2/5 ICKAPI NO: 19 city: SARIYER ISTANBUL postcode: 34467 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Turkey [TR]
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2019
Duration (year-month-day)	from 2019-12-01 to 2020-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	MEINOX ILAC TEKNOLOJILERI AS MEINOX ILAC TEKNOLOJILERI AS Organization address address: RESITPASA MAH. KATAR CAD. TEKNOKENT ARI 1 NO: 2/5 ICKAPI NO: 19 city: SARIYER ISTANBUL postcode: 34467 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TR (SARIYER ISTANBUL)	coordinator	50˙000.00

Map

Project objective

MEISi is the first innovative product of Meinox as a druggable substance, owing to its years of research on MEIS biology (published in prestigious journals like Nature and Cell Stem Cell, and PCT patented - pending national entry in 44 countries). Meinox targets the deadliest noncommunicable diseases (NCDs); cancer, CVDs and diabetes, together accounting for nearly 71% of all deaths globally. Never ending efforts and global targets in tackling these diseases show the importance of the development of more effective therapeutics.

MEISi is a druggable target-based small molecule, developed and validated by Meinox. MEISi inhibits the activity of MEIS protein which plays a critical role in cell metabolism and associated with NCDs. The benefit it presents to the targeted drug discovery market is to provide tools to modulate molecular mechanisms of the NCDs. The massive sizes of oncology and cardiovascular drug markets (USD $ 29.3B globally) indicate the significance of the small molecule drug discovery market which motivates Meinox to target €10M market share in 3 years after commercialization.

Meinox is a deep-tech startup established in 2018 with the main focus on novel and high-level pharmaceutically active ingredients. The company aims to research, develop, produce and market first-in-class, selective drug-like small molecule inhibitors of MEIS, PBX and TGIF2 proteins and their co-factor HOXA9.

Meinox aims to conduct a feasibility study with a risk analysis based on different market regulations. In order to improve the commercialization plan, potential customers of MEISi will be identified and strategies will be developed for each segment by defining proper channels for the MEISi product family. Market entry strategy will be validated by performing market analysis and competitive benchmarking in the target markets.

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The information about "MEISI" are provided by the European Opendata Portal: CORDIS opendata.

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