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MEISi SIGNED

Druggable Small Molecule Inhibitor of MEIS Proteins

Total Cost €

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EC-Contrib. €

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Partnership

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 MEISi project word cloud

Explore the words cloud of the MEISi project. It provides you a very rough idea of what is the project "MEISi" about.

pending    countries    stem    44    tgif2    deaths    pbx    massive    share    strategy    critical    indicate    substance    cell    molecule    hoxa9    published    accounting    global    national    tech    motivates    10m    competitive    cardiovascular    meis    segment    ncds    biology    regulations    conduct    ingredients    plan    performing    inhibits    small    nearly    deep    modulate    innovative    cvds    sizes    druggable    diseases    plays    co    inhibitors    29    customers    therapeutics    3b    never    pct    mechanisms    active    efforts    metabolism    proteins    oncology    class    proper    selective    owing    journals    usd    markets    benefit    family    nature    meisi    patented    benchmarking    commercialization    tackling    channels    deadliest    diabetes    ending    prestigious    company    meinox    significance    pharmaceutically    noncommunicable    2018    71    globally    startup    tools    discovery    validated    protein    cancer    market    first    risk    strategies    drug    feasibility    molecular    entry   

Project "MEISi" data sheet

The following table provides information about the project.

Coordinator
MEINOX ILAC TEKNOLOJILERI AS 

Organization address
address: RESITPASA MAH. KATAR CAD. TEKNOKENT ARI 1 NO: 2/5 ICKAPI NO: 19
city: SARIYER ISTANBUL
postcode: 34467
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Turkey [TR]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MEINOX ILAC TEKNOLOJILERI AS TR (SARIYER ISTANBUL) coordinator 50˙000.00

Map

 Project objective

MEISi is the first innovative product of Meinox as a druggable substance, owing to its years of research on MEIS biology (published in prestigious journals like Nature and Cell Stem Cell, and PCT patented - pending national entry in 44 countries). Meinox targets the deadliest noncommunicable diseases (NCDs); cancer, CVDs and diabetes, together accounting for nearly 71% of all deaths globally. Never ending efforts and global targets in tackling these diseases show the importance of the development of more effective therapeutics.

MEISi is a druggable target-based small molecule, developed and validated by Meinox. MEISi inhibits the activity of MEIS protein which plays a critical role in cell metabolism and associated with NCDs. The benefit it presents to the targeted drug discovery market is to provide tools to modulate molecular mechanisms of the NCDs. The massive sizes of oncology and cardiovascular drug markets (USD $ 29.3B globally) indicate the significance of the small molecule drug discovery market which motivates Meinox to target €10M market share in 3 years after commercialization.

Meinox is a deep-tech startup established in 2018 with the main focus on novel and high-level pharmaceutically active ingredients. The company aims to research, develop, produce and market first-in-class, selective drug-like small molecule inhibitors of MEIS, PBX and TGIF2 proteins and their co-factor HOXA9.

Meinox aims to conduct a feasibility study with a risk analysis based on different market regulations. In order to improve the commercialization plan, potential customers of MEISi will be identified and strategies will be developed for each segment by defining proper channels for the MEISi product family. Market entry strategy will be validated by performing market analysis and competitive benchmarking in the target markets.

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The information about "MEISI" are provided by the European Opendata Portal: CORDIS opendata.

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