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DISCOvERIE SIGNED

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in iRritable bowel syndrome In Europe

Total Cost €

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EC-Contrib. €

0

Partnership

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 DISCOvERIE project word cloud

Explore the words cloud of the DISCOvERIE project. It provides you a very rough idea of what is the project "DISCOvERIE" about.

leader    network    global    quality    experts    specialists    disease    tools    monitoring    pathophysiological    board    socioeconomic    comorbid    medicine    validation    chronic    prevalent    clinical    hypothesis    multidisciplinary    prognostic    differing    transversal    bowel    innovation    fatigue    syndrome    citizens    personalised    wellbeing    manifestations    43    units    physical    irritable    communication    stratify    undefined    comorbidities    media    patients    publications    technological    mental    creation    life    anxiety    smes    brain    gut    disseminate    recording    care    protocols    distorted    entity    implementing    mostly    discoverie    phenotypes    ibs    providers    europeans    arising    identification    hospital    mechanisms    physiopathological    reducing    newly    therapeutic    million    nutritional    fibromyalgia    billion    position    guides    created    patents    depression    causative    scientific    healthcare    impaired    patient    health    pharma    devastating    personalized    alone    associations    biomarkers    comprehension    reference    women    treatment    origin   

Project "DISCOvERIE" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA 

Organization address
address: PASSEIG VALL D HEBRON 119-129 EDIFICIO DE RECERCA
city: BARCELONA
postcode: 8035
website: http://www.vhir.org/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 6˙000˙000 €
 EC max contribution 6˙000˙000 € (100%)
 Programme 1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES (BARCELONA) coordinator 1˙147˙462.00
2    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 756˙435.00
3    UNIVERSITATSKLINIKUM HEIDELBERG DE (HEIDELBERG) participant 613˙312.00
4    VIB BE (ZWIJNAARDE - GENT) participant 526˙485.00
5    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 520˙792.00
6    Hycult biotechnology bv NL (Uden) participant 354˙455.00
7    UNIVERSITEIT MAASTRICHT NL (MAASTRICHT) participant 316˙272.00
8    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) participant 278˙217.00
9    EMERGENTEC BIODEVELOPMENT GMBH AT (VIENNA) participant 268˙250.00
10    ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA IT (BOLOGNA) participant 242˙574.00
11    ANAXOMICS BIOTECH SL ES (BARCELONA) participant 212˙871.00
12    UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA RO (Cluj-Napoca) participant 167˙821.00
13    SEMMELWEIS EGYETEM HU (BUDAPEST) participant 146˙534.00
14    JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN DE (FRANKFURT AM MAIN) participant 123˙762.00
15    STICHTING KATHOLIEKE UNIVERSITEIT NL (NIJMEGEN) participant 123˙762.00
16    BYTE FACTORY SYSTEMS SL ES (MATARO) participant 82˙178.00
17    CLICLAB TRANSFORMATIVE AGENT SL ES (BARCELONA) participant 60˙396.00
18    FOLLOWHEALTH SL ES (BARCELONA) participant 58˙415.00
19    NANOSTRING TECHNOLOGIES INC US (SEATTLE) participant 0.00

Map

 Project objective

Mental (anxiety and depression) and non-mental (fibromyalgia and chronic fatigue syndrome) comorbidities are highly prevalent in irritable bowel syndrome (IBS), with over 60 million Europeans affected, mostly women, by devastating manifestations, impaired treatment and quality of life. Estimated costs are €43 billion/year for IBS, mostly derived from comorbid IBS. Our hypothesis is that comorbid IBS represents a distinct clinical entity, arising from distorted brain-gut communication with a unique, specific, but undefined pathophysiological origin, differing from IBS alone. DISCOvERIE was created to advance the understanding of its causative mechanisms. Identification, validation and comprehension of these mechanisms will help stratify these patients into distinct clinical phenotypes, improving disease management, increasing quality of life and reducing socioeconomic costs. In particular, we will deliver specific comorbid-IBS physiopathological knowledge as clinical guides and protocols for newly created, hospital-based, transversal and multidisciplinary units for implementing personalized management and wellbeing of European citizens and to position Europe as a global leader in comorbid IBS personalised medicine. We will also deliver prognostic and therapeutic biomarkers and patents, technological innovation via e-health tools for personalized assessment of clinical/nutritional/physical activity and disseminate new knowledge widely. Impact will be assessed by recording media presence, scientific publications and by monitoring health-related quality of life of patients and promoting cost-effective care. To this end we have created a user board involving patient associations, clinical specialists, European healthcare experts, large pharma and SMEs representatives. We will also promote the creation of a European Reference Network for comorbid IBS involving healthcare providers across Europe.

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The information about "DISCOVERIE" are provided by the European Opendata Portal: CORDIS opendata.

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