Opendata, web and dolomites

AlzheimersInAction SIGNED

AlzheimersInAction: A multi-disciplinary approach to determine the cellular and molecular mechanisms underlying the inflammatory response to amyloid-β in Alzheimer’s disease.

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 AlzheimersInAction project word cloud

Explore the words cloud of the AlzheimersInAction project. It provides you a very rough idea of what is the project "AlzheimersInAction" about.

forms    onset    rapid    output    inflammatory    develops    biological    versatile    treatments    synaptic    difficulty    alzheimersinaction    fill    absence    comorbid    downstream    flies    completion    stages    enormous    causes    drosophila    biology    families    disciplinary    cure    neuronal    damage    activation    cell    fold    overcome    dementia    patients    alzheimer    immune    promoter    imaging    gaps    pathogenesis    difficulties    rate    urgent    beta    computational    action    actually    ad    mechanisms    slow    predicted    cells    amyloid    cellular    powerful    occurring    alarming    disease    citizens    critical    living    electrophysiology    delay    health    techniques    progression    lack    made    time    parallel    molecular    drug    economy    generates    outputs    behavioural    pathologies    lapse    symptoms    leads    capturing    devastation    cutting    nature    neurobiological    million    underlying    edge    interventions    visibility    overproduction    neurological    genetics    combines    difficult    diseases    brain    therapeutic   

Project "AlzheimersInAction" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF EDINBURGH 

Organization address
address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL
website: www.ed.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2021
 Duration (year-month-day) from 2021-09-01   to  2023-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF EDINBURGH UK (EDINBURGH) coordinator 224˙933.00

Map

 Project objective

In addition to devastation for the patients and their families, Alzheimer’s disease (AD) generates enormous costs for the wider European economy and is an urgent health priority. There are currently no drug treatments that can cure AD or other common forms of dementia. This absence of therapeutic interventions comes from a lack of understanding about the biological changes that cause most neurological diseases. It is critical to fill in the gaps in our understanding of what biological changes are occurring during the early stages of AD in order to develop treatments that could slow progression or delay the onset of AD. The comorbid nature of this disease and the difficulty of capturing neurobiological processes in action in real time have made it very difficult to determine what changes in the AD brain actually cause the synaptic and neuronal damage that leads to behavioural symptoms. To overcome these difficulties, I propose a multi-disciplinary approach that combines and develops cutting-edge techniques in Drosophila cell biology, molecular biology, time-lapse imaging, computational modelling, and electrophysiology in parallel with exploitation of the powerful molecular genetics, versatile promoter systems and rapid development of flies. Specifically, throughout AlzheimersInAction I will use these techniques to develop an in depth understanding of how an overproduction of amyloid-β causes downstream pathologies, and how activation of the immune cells during AD causes disease pathogenesis. By the completion of this project we will have a greater understanding of the cellular and molecular mechanisms underlying the inflammatory response to Aβ in Alzheimer’s disease. With 10.5 million EU citizens currently living with dementia, and this value predicted to increase at an alarming rate of 2-fold every 20 years, the outputs from AlzheimersInAction will contribute to the research output, visibility, and economy of Europe.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "ALZHEIMERSINACTION" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "ALZHEIMERSINACTION" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

PmNC (2019)

Policy-making of early nature conservation. The Netherlands and the United Kingdom compared, 1930-1960

Read More  

DNANanoProbes (2019)

Design of light-harvesting DNA-nanoprobes with ratiometric signal amplification for fluorescence imaging of live cells.

Read More  

TheaTheor (2018)

Theorizing the Production of 'Comedia Nueva': The Process of Play Configuration in Spanish Golden Age Theater

Read More