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RADIATE SIGNED

Radiation Innovations for Therapy and Education

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

RADIATE project word cloud

Explore the words cloud of the RADIATE project. It provides you a very rough idea of what is the project "RADIATE" about.

scientists capability area radiobiologists expertise students collaborations distant fails designed treatment stimulate academic radiation effort industrial academics radiobiology network international altering approximately biological 60 categories platforms surrounding strengthen patients hypotheses radiotherapy science cured premise eliminate illness good pursuit combined immune screening combating europe tumor primary community death resistance young technologies intervention translational acute sensitivity routes technological therapy preclinical metastases strategies underrepresented variety tissue methodology fragmented 45 considerable meeting therapeutic normal benefit progress excellent cancer disease outcome imaging clinicians demand outstanding innovative placed regrowth training complementary health microenvironment competitive radioresistance

Project "RADIATE" data sheet

The following table provides information about the project.

Coordinator	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.radiate.eu/
Total cost	3˙081˙061 €
EC max contribution	3˙081˙061 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2014
Funding Scheme	MSCA-ITN-ETN
Starting year	2015
Duration (year-month-day)	from 2015-03-01 to 2019-02-28

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	coordinator	546˙575.00
2	INSTITUT CURIE INSTITUT CURIE Organization address address: rue d'Ulm 26 city: PARIS postcode: 75231 website: www.curie.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	525˙751.00
3	UNIVERSITEIT MAASTRICHT UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD website: http://www.maastrichtuniversity.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	participant	510˙748.00
4	UNIVERSITE CATHOLIQUE DE LOUVAIN UNIVERSITE CATHOLIQUE DE LOUVAIN Organization address address: PLACE DE L UNIVERSITE 1 city: LOUVAIN LA NEUVE postcode: 1348 website: www.uclouvain.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LOUVAIN LA NEUVE)	participant	501˙120.00
5	TECHNISCHE UNIVERSITAET DRESDEN TECHNISCHE UNIVERSITAET DRESDEN Organization address address: HELMHOLTZSTRASSE 10 city: DRESDEN postcode: 1069 website: http://www.tu-dresden.de/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (DRESDEN)	participant	498˙432.00
6	UNIVERSITAETSKLINIKUM ESSEN UNIVERSITAETSKLINIKUM ESSEN Organization address address: HUFELANDSTRASSE 55 city: ESSEN postcode: 45147 website: www.uk-essen.de/frauenklinik/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (ESSEN)	participant	498˙432.00
7	DNA Therapeutics DNA Therapeutics Organization address address: n.a. city: Evry postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (Evry)	partner	0.00
8	DualTpharma DualTpharma Organization address address: OXFORDLAAN 55 city: MAASTRICHT postcode: 6229 EV website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	partner	0.00
9	EACR EACR Organization address address: n.a. city: Nottingham postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Nottingham)	partner	0.00
10	ESTRO ESTRO Organization address address: n.a. city: Brussels postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (Brussels)	partner	0.00
11	MAB Discovery MAB Discovery Organization address address: n.a. city: Neuried postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Neuried)	partner	0.00
12	PT THERAGNOSTIC BV PT THERAGNOSTIC BV Organization address address: OXFORDLAAN 55 BIOPARTNER BUILDING city: MAASTRICHT postcode: 6229 EV website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	partner	0.00
13	University of Szeged University of Szeged Organization address address: MASSACHUSETTS AVENUE 1350 city: CAMBRIDGE postcode: 2138 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (CAMBRIDGE)	partner	0.00
14	Vertex Pharmaceuticals Vertex Pharmaceuticals Organization address address: 86-88 Jubilee Avenue city: Abingdon postcode: OX14 4RW website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Abingdon)	partner	0.00

Map

Project objective

Approximately 45-60% of all cancer patients are treated with radiotherapy. Some of these patients have a good outcome, but in other cases their illness fails to be cured. This may result from distant metastases or from regrowth of the primary tumor. This training network is built on the premise that considerable advances in understanding radiobiology will open novel routes for effective therapeutic intervention with biological targets to improve the outcome of cancer treatment; this progress requires a European-wide effort. This network of radiobiologists, clinicians and scientists with complementary expertise will stimulate outstanding science, meeting the high demand for excellent young academics enhancing Europe´s competitive capability in this highly relevant but underrepresented and fragmented research area. We will strengthen collaborations and technological platforms to develop effective therapeutic strategies for cancer. The failure to eliminate the primary cancer can be placed into 2 categories: the radioresistance of the tumor and the sensitivity of surrounding normal tissue; and the effects of the tumor microenvironment leading to greater overall resistance and altering the immune response to the tumor. This will be combined with translational work designed to identify and implement new therapeutic strategies for use in radiotherapy. Students will benefit from the expertise of the whole, both academic and industrial including unique research technologies that will now be available throughout the network, including a variety of screening platforms, methodology for preclinical cancer therapy and novel radiation and imaging technologies. The European community will benefit from the pursuit of innovative hypotheses, training of new researchers, and dissemination of knowledge. By combating a major death-related disease in Europe this project will raise health and bring long-term benefit to the European and international community.

Deliverables

List of deliverables.
eLearning modules	Websites, patent fillings, videos etc.	2019-07-23 15:24:36
Publications	Websites, patent fillings, videos etc.	2019-07-23 15:24:57
Outreach	Websites, patent fillings, videos etc.	2019-07-23 15:24:53
PhD completion	Other	2019-07-23 15:24:48
Conferences Abstracts	Websites, patent fillings, videos etc.	2019-07-23 15:24:54
RADIATE-Gray Symposium	Other	2019-07-23 16:17:34
RADIATE International symposium	Other	2019-07-23 15:22:52
Dissemination plan	Websites, patent fillings, videos etc.	2019-07-09 09:20:58
Manual for publishing data on www.cancerdata.org	Websites, patent fillings, videos etc.	2019-07-09 09:20:58
RADIATE-EACR International Conference	Other	2019-07-09 09:20:58
Recruitment of ESRs	Other	2019-07-09 09:20:58

Take a look to the deliverables list in detail: detailed list of RADIATE deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Rekers, Nicolle H.; Olivo Pimentel, Veronica; Yaromina, Ala; Lieuwes, Natasja G.; Biemans, Rianne; Zegers, Catharina M.L.; Germeraad, Wilfred T.V.; Van Limbergen, Evert J.; Neri, Dario; Dubois, Ludwig J.; Lambin, Philippe The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses published pages: , ISSN: 2162-402X, DOI: 10.3929/ethz-b-000238558	Oncoimmunology 1	2019-07-09
2019	ValÃ©ry L. Payen, Luca X. Zampieri, Paolo E. Porporato, Pierre Sonveaux Pro- and antitumor effects of mitochondrial reactive oxygen species published pages: , ISSN: 0167-7659, DOI: 10.1007/s10555-019-09789-2	Cancer and Metastasis Reviews	2019-07-09
2018	Klaudia Szymonowicz, Sebastian Oeck, Adam Krysztofiak, Jansje van der Linden, George Iliakis, Verena Jendrossek Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells published pages: 2233, ISSN: 1422-0067, DOI: 10.3390/ijms19082233	International Journal of Molecular Sciences 19/8	2019-07-09
2017	Sebastian Oeck, Nathalie M. Malewicz, Sebastian Hurst, Klaudia Al-Refae, Adam Krysztofiak, Verena Jendrossek The Focinator v2-0 â€“ Graphical Interface, Four Channels, Colocalization Analysis and Cell Phase Identification published pages: 114-120, ISSN: 0033-7587, DOI: 10.1667/RR14746.1	Radiation Research 188/1	2019-07-09
2018	Venus Sosa Iglesias, Lorena Giuranno, Ludwig J. Dubois, Jan Theys, Marc Vooijs Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting? published pages: , ISSN: 2234-943X, DOI: 10.3389/fonc.2018.00267	Frontiers in Oncology 8	2019-07-09
2015	Mohamed Ali Mosrati, Annika MalmstrÃ¶m, Malgorzata Lysiak, Adam Krysztofiak, Martin Hallbeck, Peter Milos, Anna-Lotta Hallbeck, Charlotte BratthÃ¤ll, Michael StrandÃ©us, Marie Stenmark-Askmalm, Peter SÃ¶derkvist TERT promoter mutations and polymorphisms as prognostic factors in primary glioblastoma published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.4389	Oncotarget 6/18	2019-07-09
2018	Sebastian Oeck, Klaudia Szymonowicz, Gesa Wiel, Adam Krysztofiak, Jamil Lambert, Benjamin Koska, George Iliakis, Beate Timmermann, Verena Jendrossek Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons published pages: 3779, ISSN: 1422-0067, DOI: 10.3390/ijms19123779	International Journal of Molecular Sciences 19/12	2019-07-09
2018	Bastien Doix, Estelle Bastien, Alix Rambaud, AdÃ¡n Pinto, Caroline Louis, Vincent GrÃ©goire, Olivier Riant, Olivier Feron Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions published pages: , ISSN: 2234-943X, DOI: 10.3389/fonc.2018.00393	Frontiers in Oncology 8	2019-07-09
2017	Vincent F. Van HÃ©e, Daniel Labar, GwenaÃ«l Dehon, Debora Grasso, Vincent GrÃ©goire, Giulio G. Muccioli, RaphaÃ«l FrÃ©dÃ©rick, Pierre Sonveaux \"Radiosynthesis and validation of (±)-[¹⁸F]-3-fluoro-2-hydroxypropionate ([¹⁸F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors\" published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.14705	Oncotarget	2019-07-09
2016	Angela Diana, Lai Mun Wang, Zenobia Dâ€™Costa, Paul Allen, Abul Azad, Michael A. Silva, Zahir Soonawalla, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel, Emmanouil Fokas Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.10038	Oncotarget	2019-07-09
2017	Pierre Danhier, Piotr BaÅ„ski, ValÃ©ry L Payen, Debora Grasso, Luigi Ippolito, Pierre Sonveaux, Paolo E Porporato Cancer metabolism in space and time: Beyond the Warburg effect published pages: , ISSN: 0005-2728, DOI: 10.1016/j.bbabio.2017.02.001	Biochimica et Biophysica Acta (BBA) - Bioenergetics	2019-07-09
2016	Jhudit PÃ©rez-Escuredo, Vincent F. Van HÃ©e, Martina Sboarina, Jorge Falces, ValÃ©ry L. Payen, Luc Pellerin, Pierre Sonveaux Monocarboxylate transporters in the brain and in cancer published pages: 2481-2497, ISSN: 0167-4889, DOI: 10.1016/j.bbamcr.2016.03.013	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1863/10	2019-07-09
2016	Angela Diana, Lai Mun Wang, Zenobia Dâ€™Costa, Abul Azad, Michael A. Silva, Zahir Soonawalla, Paul Allen, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel, Emmanouil Fokas Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.12022	Oncotarget	2019-07-09

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