Explore the words cloud of the SAPHELY project. It provides you a very rough idea of what is the project "SAPHELY" about.
The following table provides information about the project.
Coordinator |
UNIVERSITAT POLITECNICA DE VALENCIA
Organization address contact info |
Coordinator Country | Spain [ES] |
Project website | https://saphely.eu/ |
Total cost | 3˙228˙838 € |
EC max contribution | 3˙228˙838 € (100%) |
Programme |
1. H2020-EU.2.1.1.6. (Micro- and nanoelectronics and photonics: Key enabling technologies related to micro- and nanoelectronics and to photonics, covering also quantum technologies) |
Code Call | H2020-ICT-2014-1 |
Funding Scheme | RIA |
Starting year | 2015 |
Duration (year-month-day) | from 2015-02-01 to 2018-07-31 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | UNIVERSITAT POLITECNICA DE VALENCIA | ES (VALENCIA) | coordinator | 945˙704.00 |
2 | MICROFLUIDIC CHIPSHOP GMBH | DE (JENA) | participant | 443˙750.00 |
3 | APR TECHNOLOGIES AB | SE (ENKOEPING) | participant | 370˙081.00 |
4 | AALBORG UNIVERSITET | DK (AALBORG) | participant | 344˙915.00 |
5 | UNIVERSITY OF EAST ANGLIA | UK (NORWICH) | participant | 323˙513.00 |
6 | MICROTEC GESELLSCHAFT FUR MIKROTECHNOLOGIE MBH | DE (DUISBURG) | participant | 226˙250.00 |
7 | Fundación Instituto Valenciano de Oncología | ES (VALENCIA) | participant | 215˙625.00 |
8 | EV GROUP E. THALLNER GMBH | AT (ST FLORIAN AM INN) | participant | 207˙750.00 |
9 | MEDICAL ENGINEERING TECHNOLOGIES LTD | UK (DOVER) | participant | 151˙250.00 |
The SAPHELY project focuses on the development and the preclinical validation of a nanophotonic-based handheld point-of-care (POC) analysis device for its application to the minimally-invasive early diagnosis of diseases, with a focus in cancer. Disease identification will be based in the fast (<5 minutes), ultra-sensitive (sub-pM) and label-free detection of novel highly-specific microRNA (miRNA) biomarkers, using a small volume of whole blood (<100 μL). This POC analysis device, which will have a low cost (envisaged cost < €3000), will significantly help in the implementation of mass screening programs, with the consequent impact on clinical management, reducing also costs of treatments, and increasing survival rates. The ultra-high sensitivity required for the direct detection of miRNA biomarkers present in the bloodstream will be achieved by using a novel sensing amplification technique. This technique is based in the use of molecular beacon capture probes with an attached high index nanoparticle, so that the hybridization events are translated into the displacement of these nanoparticles from the sensor surface. The use of this self-amplification technique avoids the use of complex PCR-based amplification methods or labelling processes, which are difficult to implement on-chip. The cost, size and weight reduction required for deploying an affordable handheld POC device will be achieved by using a novel power-based readout scheme for photonic bandgap sensing structures where the use of expensive, bulky and heavy tuneable lasers and spectrometers is avoided. Special attention will be paid within the SAPHELY project to explore the potential deployment and commercialisation of the analysis device, by means of the involvement of relevant academic and industrial partners, as well as end users.
year | authors and title | journal | last update |
---|---|---|---|
2017 |
Maria-Jose Bañuls, Pilar Jiménez-Meneses, Albert Meyer, Jean-Jacques Vasseur, François Morvan, Jorge Escorihuela, Rosa Puchades, Ãngel Maquieira Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol–Ene or Thiol–Yne Coupling Chemistry published pages: 496-506, ISSN: 1043-1802, DOI: 10.1021/acs.bioconjchem.6b00624 |
Bioconjugate Chemistry 28/2 | 2019-05-30 |
2018 |
Ãngela Ruiz-Tórtola, Francisco Prats-QuÃlez, Daniel González-Lucas, MarÃa-José Bañuls, Ãngel Maquieira, Guy Wheeler, Tamas Dalmay, Amadeu Griol, Juan Hurtado, Jaime GarcÃa-Rupérez High sensitivity and label-free oligonucleotides detection using photonic bandgap sensing structures biofunctionalized with molecular beacon probes published pages: 1717, ISSN: 2156-7085, DOI: 10.1364/BOE.9.001717 |
Biomedical Optics Express 9/4 | 2019-05-30 |
2018 |
Ãngela Ruiz-Tórtola, Francisco Prats-QuÃlez, Daniel González-Lucas, MarÃa-José Bañuls, Ãngel Maquieira, Guy Wheeler, Tamas Dalmay, Amadeu Griol, Juan Hurtado, Helge Bohlmann, Reiner Götzen, Jaime GarcÃa-Rupérez Experimental study of the evanescent-wave photonic sensors response in presence of molecular beacon conformational changes published pages: e201800030, ISSN: 1864-063X, DOI: 10.1002/jbio.201800030 |
Journal of Biophotonics | 2019-05-30 |
2015 |
Catarina Oliveira Silva, Steffen B. Petersen, Catarina Pinto Reis, PatrÃcia Rijo, Jesús Molpeceres, Henrik Vorum, Maria Teresa Neves-Petersen Lysozyme Photochemistry as a Function of Temperature. The Protective Effect of Nanoparticles on Lysozyme Photostability published pages: e0144454, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0144454 |
PLOS ONE 10/12 | 2019-05-30 |
2017 |
Daniel González-Lucas, MarÃa-José Bañuls, Jaime GarcÃa-Rupérez, Ãngel Maquieira Covalent attachment of biotinylated molecular beacons via thiol-ene coupling. A study on conformational changes upon hybridization and streptavidin binding published pages: 3231-3238, ISSN: 0026-3672, DOI: 10.1007/s00604-017-2310-4 |
Microchimica Acta 184/9 | 2019-05-30 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SAPHELY" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "SAPHELY" are provided by the European Opendata Portal: CORDIS opendata.