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VesSenDrugDeliv

A versatile platform for the design of targeting drug delivery vesicles

Total Cost €

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EC-Contrib. €

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Partnership

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Project "VesSenDrugDeliv" data sheet

The following table provides information about the project.

Coordinator
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE 

Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ
website: http://www.imperial.ac.uk/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://shaodongzhang-msca.weebly.com
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-07-01   to  2017-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE UK (LONDON) coordinator 195˙454.00

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 Project objective

In the project of Marie Sklodowska-Curie Fellowship, I will design a versatile molecular platform that is used to construct multifunctional amphiphiles, which co-assemble with amphiphilic gold nanoparticles (AuNPs) to form monodisperse and stable targeting drug delivery vesicles. By incorporating multiple targeting ligands and multiple hydrophilic and hydrophobic drugs, I aim to discover efficient vesicle formulation with increased targeting selectivity and potent cytotoxicity to tumor cells. The route of the targeted drug delivery will be followed spontaneously via transiting surface plasmon resonance of AuNPs, and the impact of the targeted drug delivery on the targeted tumor cells will be monitored in real time by live cell Raman micro-spectroscopy. Furthermore, any targeting ligand, hydrophilic and hydrophobic drug can be easily tuned for a variety of different targeted tumour cells.

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