The page lists 162 projects related to the topic "ligand".
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1 | COMPUCELL | Autonomous Cellular Computers for Diagnosis | 2015 |
2 | SILENCE | Mechanisms of Gene Silencing by the Glucocorticoid Receptor | 2015 |
3 | Crosstag | Unravelling cross-presentation pathways using a chemical biology approach | 2015 |
4 | DE-ORPHAN | DEtermination of Orphan Receptor PHysiological Agonists and sigNals | 2015 |
5 | GLYCO-TOOLS | Bio-Inspired Tools for Glycoscience | 2015 |
6 | NONNH | Mechanism of hydrogenation and transfer hydrogenation of polar unsaturations catalyzed by non N-H systems | 2015 |
7 | DEGENHA | Delivering Hydroacylation: A General and Enantioselective Process | 2015 |
8 | AsymHalogenation | Intermolecular Asymmetric Halogenations of Olefins | 2015 |
9 | BAIPFeOTC | Bis(alkyl-imidazolyl)propionate (BAIP) based bio-inspired mono-nuclear non-heme iron(II) complexes that catalyze challenging oxidative transformations of organic compounds | 2015 |
10 | CHLOROIRIDOIDS | Elusive enzymes with biocatalytic potential: chlorinases in the plant kingdom | 2015 |
11 | ChiralCatLnCoils | De novo design of Lanthanide coiled coils for asymmetric catalysis | 2015 |
12 | MaSCheNav | Mass Spectrometry-Based Chemoproteomic Profiling of Nav1.7, a Voltage-Gated Sodium Channel | 2015 |
13 | MANGANOXI | The development of manganese-based alkene epoxidation, cis-dihydroxylation and alkane C-H oxidation catalysts | 2015 |
14 | MIP4CELL | Molecular Imprinting mediated regulation of cell behavior and related biomedical applications | 2016 |
15 | VesSenDrugDeliv | A versatile platform for the design of targeting drug delivery vesicles | 2015 |
16 | nAChR PAM-to-gate | Gating mechanism and pharmacological modulation of nicotinic acetylcholine receptors | 2015 |
17 | MEMBRANEPROT | Membrane proteins – development of new computational approaches and its application to G-Protein Coupled Receptors | 2016 |
18 | CoopClickCat | CoopClickCat | 2015 |
19 | Ni-CAT | Ni-CAT | 2015 |
20 | VERTICAL CITY | Versatility of scaffold complexes in vivo to control synaptic plasticity | 2015 |
21 | ICaRO | Ion Channels and Receptors Operation | 2016 |
22 | RotaxHEC | Click to Lock: Mechanically Interlocked Architectures as Hydrogen Evolving Catalysts | 2015 |
23 | CaSR Biomedicine | Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases | 2016 |
24 | VARMET | Variational Metadynamics | 2016 |
25 | ImmunityByPairDesign | Design and redesign of a plant immune receptor complex | 2015 |
26 | uPET | Molecular imaging and targeted therapy of the aggressive phenotype: development of uPAR theranostics for cancer patients | 2015 |
27 | PolyDrug Discovery | Discovery of anticancer polymeric drugs that mimic the action of TRAIL | 2016 |
28 | LDC4PCaTher | BMX-targeted ligand-drug conjugates for prostate cancer therapy | 2016 |
29 | RiboDisc | Discovery of novel orphan riboswitch ligands | 2016 |
30 | PhotoSMM | Single Molecule Magnets light-switching with photochromic ligands | 2016 |
31 | NEUTRO-LILR | Leukocyte immunoglobulin-like receptors (LILRs) on neutrophils | 2016 |
32 | BiMetArylation | Bimetallic catalytic arylation of simple arenes | 2016 |
33 | TransNic | Enantioselective Nickel-Catalyzed trans-Carbometallative Couplings and Cyclizations | 2016 |
34 | G4-PTROs | Regulatory network of G-quadruplex dependent Post-Transcriptional mRNA Operons (PTROs) | 2016 |
35 | MCANALSMSCA2015 | Receptor signalling in space and time - Gaining high-resolution information of the temporal and spatial control of G protein-coupled receptor signalling. | 2018 |
36 | ChemoSense | Elucidating the Mechanisms of Insect’s Chemical Taste to Understand Specific Host-Plant Selection | 2016 |
37 | CorCir | Cortical circuit assembly in the developing mouse neocortex | 2017 |
38 | PERSIST | Systematic identification of (p)ppGpp-dependent multidrug and stress tolerance factors | 2016 |
39 | DynaSpaCER | Molecular Mechanisms of Dynamic and Spatial Control of Eph Receptors clustering | 2016 |
40 | MID | Molecular Information Dynamics | 2016 |
41 | REFOLDAMER | Communication through Polarity-Switchable Foldamers | 2016 |
42 | ColloQuantO | Colloidal Quantum Dot Quantum Optics | 2016 |
43 | IL-E-CAT | Enhancing electrocatalysis in low temperature fuel cells by ionic liquid modification | 2016 |
44 | illumizymes | Illuminating aptamers and ribozymes for biomolecular tagging and fluorogen activation | 2016 |
45 | CF_struct | High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator | 2016 |
46 | DLL4-LVN | Targeting the (pre)metastatic lympho-vascular niche: molecular mechanisms and therapeutic implications in melanoma | 2017 |
47 | FeREDCOUPLS | FeREDCOUPLS - Reduced Iron Catalysts for Reduction and Coupling Reactions | 2016 |
48 | SINCHAIS | In situ analysis of single channel subunit composition in neurons: physiological implication in synaptic plasticity and behavior | 2016 |
49 | SUSCAT | New Directions in Sustainable Catalysis by Metal Complexes | 2016 |
50 | AEDNA | Amorphous and Evolutionary DNA Nanotechnology | 2016 |
51 | ULT-MAS-DNP | Dynamic Nuclear Polarization at ultra-fast sample spinning and ultra-low temperature | 2016 |
52 | MARS | Mechanism of allosteric regulation of SHP2 phosphatase and its role in cancer and geneticdiseases: a multidisciplinary computational, structural and biological approach | 2017 |
53 | FAST-BM | FAST-BM: FibroSelect: delivering A Step-change in Biotherapeutic Manufacturing | 2016 |
54 | AlCat | Bond activation and catalysis with low-valent aluminium | 2017 |
55 | RAMSES | Reactivity and Assembly of Multifunctional, Stimuli-responsive Encapsulation Structures | 2016 |
56 | MMA | Molecular Mechanical Adhesives | 2017 |
57 | SWEETBULLETS | Sweet Theranostics in Bitter Infections - Seek and Destroy | 2017 |
58 | B-SMART | Brain-Specific, Modular and Active RNA Therapeutics | 2017 |
59 | CD40-INN | CD40 goes innate: defining and targeting CD40 signaling intermediates in the macrophage to treat atherosclerosis | 2016 |
60 | LanAsCat | Lanthanides as electron Dimmer switch in organometallic catalysis | 2017 |
61 | Neuroheart | Cardiovascular Molecular Imaging for Personalized Tailored Treatment | 2017 |
62 | REDOX SHIELDS | Protection of Redox Catalysts for Cathodic Processes in Redox Matrices. | 2017 |
63 | THZCALORIMETRY | Time Resolved THz Calorimetry explores Molecular Recognition Processes | 2016 |
64 | Bioisotopes | Biological Effects on Isotopically Evaluated Systems | 2017 |
65 | Terpy2DMat | Tuning of 2D materials properties through controlled functionalization with opto-electroactive complexes | 2017 |
66 | HIGH-GEAR | High-valent protein-coordinated catalytic metal sites: Geometric and Electronic ARchitecture | 2017 |
67 | TRPLigDrugConj | TRPV1-targeted ligand-drug conjugates to treat prostate cancer | 2017 |
68 | GD TCR LIGAND | Identification of the ligand of a human public anti-HCMV/cancer γδ T cell receptor | 2017 |
69 | Ti-EM | Methodological developments for time-resolved single particle cryo-EM | 2017 |
70 | OMICS | Origami-based Microfluidic Interface for Cell Signalling | 2017 |
71 | meltRBP | Tracking interactions between RNA and RNA-binding proteins by thermal profiling of the proteome | 2017 |
72 | BRAINHIB | Integrated drug discovery approach to generate brain-penetrant inhibitors of glioblastoma cell proliferation | 2018 |
73 | TSPO METALLODRUGS | Novel, highly effective and selective anticancer metallodrugs | 2018 |
74 | Cytokine Signalosome | Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands | 2017 |
75 | DualFun | Dual Function Polymer Materials for Blood Contacting Applications | 2017 |
76 | ASSP | Advanced Self-sorting and Supramolecular Polymers | 2017 |
77 | PHOTORNA | Development of photoswitchable ligands for the reversible and selective assembly with RNA | 2017 |
78 | WallWatchers | Plant cell wall communication and remodelling: the wall watchers. | 2017 |
79 | NascenTomiX | Ribosome inhibition by nascent or antimicrobial peptides | 2017 |
80 | FocAd | Structural Studies on Focal Adhesions | 2017 |
81 | Glyco-Platforms | Novel smart glyco-nanomaterials as targeted therapeutics. | 2017 |
82 | PHAGO | Inflammation and AD: modulating microglia function focussing on TREM2 and CD33 - Sofia ref.: 115976 | 2016 |
83 | CALCEAM | Cooperative Acceptor Ligands for Catalysis with Earth-Abundant Metals | 2017 |
84 | ONCOSYSTEMS | Phenotypic characterization of Liver-derived exosomes populations associated with liver metastasis in pancreatic cancers | 2017 |
85 | MoQuOS | Molecular Quantum Opto-Spintronics | 2017 |
86 | FRAGMENT2DRUG | Jigsaw puzzles at atomic resolution: Computational design of GPCR drugs from fragments | 2017 |
87 | BETACONTROL | Control of amyloid formation via beta-hairpin molecular recognition features | 2017 |
88 | gdTCR-Ligand | Investigating the recognition of a novel ligand by gamma-delta T cells and the translation of this interaction into molecules for future cancer immunotherapy | 2017 |
89 | GET-UP BAT | GPCR Exploitation To Unlock the Power of Brown/Beige Adipose Tissue | 2017 |
90 | CylcoRu4PACT | Cyclometallated ruthenium complexes for photo-activated chemotherapy | 2018 |
91 | SI | Structural and functional characterization of the ICOS/ICOSL immune complex | 2018 |
92 | iPS-ChOp-AF | Combining induced pluripotent stem cells, tissue engineering, optogenetic and chemogenetic concepts for the study and treatment of atrial fibrillation | 2018 |
93 | SYNFOS | Synthetic toolkit for fragment oriented synthesis | 2018 |
94 | MOOiRE | Mix-in Organic-InOrganic Redox Events for High Energy Batteries | 2018 |
95 | STREAM | Statistical Tools for Reaction Efficacy AssessMent: Prediction and Understanding in Organocatalyst Discovery | 2018 |
96 | CaLecLig | Calcium-dependent Lectins in Human Pathogenic Infections: From Atomistic Understanding to Ligand Design | 2018 |
97 | CROWDASSAY | Folding Pathways of DNA G-quadruplexes in Crowding Conditions, and Implications for Mass Spectrometry-based Ligand Screening Assays | 2018 |
98 | PREMHYDRO | PROBING REACTION MECHANISMS IN PHOTOCATALYTIC H2 GENERATION | 2018 |
99 | BREFMC2017 | Deciphering the function(s) of the C-type lectin DCIR/CLEC4A in tuberculosis | 2018 |
100 | CuCAN | Asymmetric Copper Catalyzed Multicomponent Coupling | 2018 |
101 | DC-SIGN-MFN | Dissecting Multivalent Viral Receptor-carbohydrate Interactions Using Polyvalent Multifunctional Glycan-Quantum Dot | 2018 |
102 | IMMUNO-PEPTALK | Regulation of plant receptor kinase-mediated immunity by endogenous peptides and their receptors | 2018 |
103 | RECGLYCANMR | Breaking the limits in glycan recognition by NMR | 2018 |
104 | Za-AV | Determination of physiologically relevant RNA substrate(s) and design of small-molecule inhibitors for Zα domains as potential intervention strategies for viral infections and autoimmunity | 2018 |
105 | RuZn | Ru–Zn Heterobimetallic Complexes | 2018 |
106 | MOSPhotocat | Application of Metal Oxide Semiconductors in Photocatalysis | 2018 |
107 | rSAMs-NANO | Nanoparticles with switchable shells for virus sensing and inhibition | 2018 |
108 | THALLMORPHAL | Insight into the Symbiotic Chemical Communication of Algae and Bacteria: Thallusin and Dedicated Analogues | 2018 |
109 | DETRIMODE | DEgradation TRIggered by MOdular DEsign | 2018 |
110 | MOCCA | Metal-Organic Cages for Catalysis Applications | 2018 |
111 | UNNAMEd-2 | Unraveling the conceptional novel ADAM17 regulation by PP2A in metastasis formation. | 2019 |
112 | Gold3Cat | (P,C) and (O,O) well-defined gold(III) complexes for the development of new gold(III) catalytic processes | 2018 |
113 | MATURE-NK | MAnufacturing of TUmour-REactive Natural Killer cells | 2018 |
114 | SUPRAWOC | Supramolecular Architectures for Ruthenium Water Oxidation Catalysis | 2018 |
115 | UBioRec | Development and Testing of a Reference Computational Platform for Understanding BiomolecularRecognition | 2018 |
116 | AlloGPCR | Allosteric modulation of G-protein Coupled Receptors conformational landscape | 2018 |
117 | DYNACOTINE | Signal transduction and allosteric modulation of nicotinic acetylcholine receptors:from ion channel electrophysiology to atomic 3D structures | 2019 |
118 | DISCOVER | Death receptor signalling in tumour immune editing | 2018 |
119 | FlyGutHomeostasis | Identification of paracrine and systemic signals controlling adult stem cell activity and organ homeostasis | 2019 |
120 | iGLURs - A NEW VIEW | Exposing nature’s view of ligand recognition in ionotropic glutamate receptors | 2019 |
121 | GLIOVACC | Augmenting and broadening T-cell responses to glioblastoma - therapeutic vaccine platform based on HCMV expressing NKG2D ligands | 2018 |
122 | ENDOSCAPE | ENDOSCAPE, a clinically applicable non-viral gene delivery technology | 2019 |
123 | HelixMold | Computational design of novel functions in helical proteins by deviating from ideal geometries | 2019 |
124 | HYPROTIN | Hyperpolarized Nuclear Magnetic Resonance Spectroscopy for Time-Resolved Monitoring of Interactions of Intrinsically Disordered Breast-Cancer Proteins | 2019 |
125 | MOF-reactors | Metal-Organic Frameworks as Chemical Reactors for the Synthesis of Well-Defined Sub-Nanometer Metal Clusters | 2019 |
126 | F-ELEMENT_ARCHITECT | Building Precise Molecular Architectures to Unlock Remarkable f-Element Properties | 2019 |
127 | HighPotOx | Exploring the Limits of High Potential OxidizersPrediction, Validation and Preparation of Unusual Molecules at the Edge of Stability | 2020 |
128 | SpartWISE | Reinventing fine chemicals synthesis: large-scale production of sparteine from lupin beans | 2019 |
129 | EV-2C | Structural and functional studies of enterovirus 2C proteins: promising targets for antiviral therapy. | 2019 |
130 | hsPCF-FRET | Real-time characterisation of neuropeptide binding to a membrane receptor involved in pain and ischemic stroke | 2019 |
131 | GPCR-MS | Molecular Details of Membrane Protein Receptor Dynamics | 2019 |
132 | APTAFRAME | DNA-origami frame platform for co-evolution ligand selection | 2019 |
133 | DEEPCAT | Degradable Polyolefin Materials Enabled by Catalytic Methods | 2019 |
134 | SURFCAT | Surface-functionalised nanocrystal catalysts for the electrochemical reduction of carbon dioxide | 2020 |
135 | SQSig | Oligo-Squaramide Rigid-Rods for Artificial Transmembrane Signaling | 2020 |
136 | Au-MLC | Cooperative Au catalysis with chemically non-innocent ligands. | 2019 |
137 | CatchGel | Catch Bond Cross-linked Hydrogels | 2020 |
138 | BioNanoProbes | Bio-Inspired Glycan-NanoProbes as Antimicrobial Pro-Drugs | 2019 |
139 | microPhage | Automated microfluidic phage display through non-fouling droplet-based technologies | 2020 |
140 | BiMetaCat | Two Are Better Than One: Bimetallic Catalysts for the Conversion of Lignin-Derived Aryl-Ethers | 2019 |
141 | MIMIC | Mapping and modulating integrin mediated interactions | 2020 |
142 | MIMIC | Deciphering how microbiota modulate anti-tumor immune responses in checkpoint therapy | 2020 |
143 | signalling dynamics | Bridging biophysics and cell biology: The role of G protein-coupled receptor conformations in signalling | 2020 |
144 | SynProAtCell | Delivery and On-Demand Activation of Chemically Synthesized and Uniquely Modified Proteins in Living Cells | 2019 |
145 | Sperm-Egg Phusion | Unexpected connections between a phagocytic machinery and mammalian fertilization | 2019 |
146 | MADMpancreas | Using the precision mouse genetic tool MADM to elucidate the role of EGFR in directing beta cell differentiation and pancreatic morphogenesis | 2019 |
147 | UNPACK PD-L1 | Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells | 2020 |
148 | SCHENGEN-ROOT | 'Filling the gaps' in the Schengen pathway for plant root Casparian strip integrity | 2020 |
149 | PoInt | Principles of Integrin Mechanics and Adhesion | 2019 |
150 | ARGO | The Quest of the Argonautes - from Myth to Reality | 2019 |
151 | TAcTIC | TArgeTed molecular Imaging and surgery for gastro-intestinal Cancer | 2019 |
152 | Angio-NYT | Investigating the crosstalk between Notch and YAP/TAZ in sprouting angiogenesis | 2020 |
153 | TRACER | TRAF-STOP therapy to reduCe inflammation in athERosclerosis. | 2020 |
154 | CCIMC | Coordination chemistry inspires molecular catalysis | 2020 |
155 | mRNA NanoDeli | Application of RNA nanotechnology for delivery of mRNA therapeutics | 2019 |
156 | CHANCE | Structure guided inhibition of IDOL to treat atherosclerosis and the metabolic syndrome | 2019 |
157 | SYNVIVO | Revealing dendritic cell-CD4+ T cell communication by using synthetic biology in vivo | 2020 |
158 | STI-001 | Turn Cancer Immunotherapy Effective in Most Patients | 2019 |
159 | H I C I | Transcriptional and epigenetic control of tissue regenerative HB-EGF in autoimmune CNS inflammation | 2020 |
160 | NANOVR | Nanoscale Design using Virtual Reality | 2020 |
161 | RECOBIN-PROTACs | Reversible Covalently Binding PROTACs Technology for Protein Degradation in Cancer Therapy | 2020 |
162 | CuZnSyn | Understanding Copper–Zinc Synergy for Carbon Dioxide Hydrogenation | 2020 |