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GLASSIX SIGNED

Improved metallic GLASses for Small Implants through X-ray and biological characterisation of corrosion products

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

GLASSIX project word cloud

Explore the words cloud of the GLASSIX project. It provides you a very rough idea of what is the project "GLASSIX" about.

biocompatibility inflammation commercial damaging mechanically ti cutting anthogyr situ local resistance mechanical hearing carry simulated edge translated rays assisted shown human usually er synchrotron corrosion host glassix readily alloy passive environment metal ray fed dental academic damage glasses crevice tested biomedical manufacturer particles clinical back surrounding tissue implants good anchored combines expertise standard cells manufacture surfaces characterisation equip small bone generate metallic feasibility aids macc

Project "GLASSIX" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY OF BIRMINGHAM Organization address address: Edgbaston city: BIRMINGHAM postcode: B15 2TT website: www.bham.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.researcherid.com/rid/D-2337-2011
Total cost	195˙454 €
EC max contribution	195˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-EF-ST
Starting year	2015
Duration (year-month-day)	from 2015-11-01 to 2017-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY OF BIRMINGHAM THE UNIVERSITY OF BIRMINGHAM Organization address address: Edgbaston city: BIRMINGHAM postcode: B15 2TT website: www.bham.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BIRMINGHAM)	coordinator	195˙454.00

Map

Project objective

Small metal implants such as dental implants or bone-anchored hearing aids need very good mechanical properties and corrosion resistance to avoid local inflammation and remain integrated in bone. In GLASSIX, Ti-based metallic glasses will be developed specifically for small implants using a new approach to evaluate biocompatibility. This is usually tested on passive metal surfaces, but recent work has shown that mechanically-assisted crevice corrosion (MACC) can generate metal particles and corrosion products that damage the surrounding tissue. In situ characterisation of corrosion products with synchrotron X-rays will be used to design standard simulated corrosion products that will then be tested on human cells to evaluate which corrosion products are most damaging. The findings from this new approach will be fed back into the alloy development process together with information on feasibility of manufacture from Anthogyr, a leading manufacturer. The project combines the ER’s expertise in metallic glasses, and the expertise of host researchers in corrosion, X-ray methods, clinical and biomedical research, and will equip the ER to carry out cutting edge research in an academic environment that can readily be translated into clinical and commercial success in the biomedical devices sector.

Publications

List of publications.
year	authors and title	journal	last update
2017	Yue Zhang, Owen Addison, Petre Flaviu Gostin, Alexander Morrell, Angus J. M. C. Cook, Alethea Liens, Jing Wu, Konstantin Ignatyev, Mihai Stoica, Alison Davenport In-Situ Synchrotron X-ray Characterization of Corrosion Products in Zr Artificial Pits in Simulated Physiological Solutions published pages: C1003-C1012, ISSN: 0013-4651, DOI: 10.1149/2.0671714jes	Journal of The Electrochemical Society 164/14	2019-06-17

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The information about "GLASSIX" are provided by the European Opendata Portal: CORDIS opendata.