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PRe-FActo

Periodontal Regeneration through Femtosecond laser Action

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 PRe-FActo project word cloud

Explore the words cloud of the PRe-FActo project. It provides you a very rough idea of what is the project "PRe-FActo" about.

phosphates    monty    clinical    materials    material    disciplinary    engineering    leeds    intervened    tooth    training    investigation    health    disease    outcome    tests    characterization    cross    gel    collagen    fibroblasts    cerium    cell    jha    area    antibacterial    doped    public    erbium    supervisor    photo    synthesis    revival    am    sintered    risks    prevention    say    beneficial    dynamic    densified    chitosan    scientific    exploring    culture    aj    histological    bonded    aluminum    duggal    global    irradiation    host    fellow    tested    career    supplemented    rounded    toxicology    periodontium    successful    bioengineer    sintering    ions    ultrafast    potentially    academic    animesh    fellowship    oxides    pulsed    uol    university    attachment    prof    regenerative    mixed    femtosecond    periodontitis    calcium    biomaterial    facto    listed    researcher    effect    supervision    skills    qualified    pursuing    surface    therapy    fluoride    deal    topology    lasers    laser    drug    rtas   

Project "PRe-FActo" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://aanastasiou83.wixsite.com/prefacto
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00

Map

 Project objective

The PRE-Facto fellowship aims to develop a new regenerative approach which potentially will promote the revival of the periodontium, while a successful outcome may lead also to the prevention of the disease when intervened early. Within my research I am going to develop a new biomaterial (calcium phosphates doped with ions of say, cerium and erbium oxides, fluoride and aluminum (3) ions) with antibacterial properties which will be densified and bonded on the tooth surface after the irradiation with an ultrafast pulsed laser (femtosecond laser). In order to promote the attachment of the fibroblasts, the biomaterial will be mixed with collagen gel (or chitosan) while the effect of the surface topology will be also tested. For my research training as a bioengineer within which I aim to solve periodontitis as a global problem I will deal with the following Research Training Activities (RTAs); i) Synthesis, characterization and delivery of the biomaterial; ii) Sintering of the materials with femtosecond laser - characterization of the sintered area; iii) Cell culture and histological studies for exploring the regenerative potential of the material; iv) Toxicology tests and potential risks investigation. This training is not only beneficial for the fellow’s scientific career development, but also for the host institute (the University of Leeds) and the general public health. The above listed training activities will be supplemented by a number of non-Technical skills for my career development. As a result of this cross-disciplinary project the fellow will be a well-rounded bioengineer researcher who in future will be become qualified for pursuing an academic career at the University of Leeds in the area of advanced drug delivery and photo-dynamic therapy using novel femtosecond lasers. Necessary research training and supervision at the UoL will be provided by the Engineering supervisor Prof. Animesh Jha (AJ) and the clinical supervisor Prof . Monty Duggal.

 Publications

year authors and title journal last update
List of publications.
2018 A.D. Anastasiou, S. Strafford, C.L. Thomson, J. Gardy, T.J. Edwards, M. Malinowski, S.A. Hussain, N.K. Metzger, A. Hassanpour, C.T.A. Brown, A.P. Brown, M.S. Duggal, A. Jha
Exogenous mineralization of hard tissues using photo-absorptive minerals and femto-second lasers; the case of dental enamel
published pages: , ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.02.012
Acta Biomaterialia 2019-06-18

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