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PRe-FActo

Periodontal Regeneration through Femtosecond laser Action

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 PRe-FActo project word cloud

Explore the words cloud of the PRe-FActo project. It provides you a very rough idea of what is the project "PRe-FActo" about.

cerium    host    mixed    materials    biomaterial    skills    revival    successful    global    prevention    collagen    antibacterial    gel    histological    prof    effect    aluminum    scientific    pulsed    training    listed    bonded    university    calcium    monty    say    tests    fluoride    potentially    aj    topology    culture    erbium    densified    sintered    beneficial    rtas    clinical    intervened    animesh    irradiation    area    periodontium    therapy    supplemented    synthesis    outcome    regenerative    characterization    academic    oxides    public    cell    disciplinary    facto    investigation    fellowship    fibroblasts    duggal    am    chitosan    fellow    attachment    surface    qualified    risks    sintering    supervision    researcher    phosphates    engineering    doped    tooth    ultrafast    lasers    deal    supervisor    tested    periodontitis    leeds    toxicology    ions    femtosecond    material    bioengineer    pursuing    dynamic    laser    disease    cross    exploring    career    uol    rounded    health    drug    jha    photo   

Project "PRe-FActo" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://aanastasiou83.wixsite.com/prefacto
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00

Map

 Project objective

The PRE-Facto fellowship aims to develop a new regenerative approach which potentially will promote the revival of the periodontium, while a successful outcome may lead also to the prevention of the disease when intervened early. Within my research I am going to develop a new biomaterial (calcium phosphates doped with ions of say, cerium and erbium oxides, fluoride and aluminum (3) ions) with antibacterial properties which will be densified and bonded on the tooth surface after the irradiation with an ultrafast pulsed laser (femtosecond laser). In order to promote the attachment of the fibroblasts, the biomaterial will be mixed with collagen gel (or chitosan) while the effect of the surface topology will be also tested. For my research training as a bioengineer within which I aim to solve periodontitis as a global problem I will deal with the following Research Training Activities (RTAs); i) Synthesis, characterization and delivery of the biomaterial; ii) Sintering of the materials with femtosecond laser - characterization of the sintered area; iii) Cell culture and histological studies for exploring the regenerative potential of the material; iv) Toxicology tests and potential risks investigation. This training is not only beneficial for the fellow’s scientific career development, but also for the host institute (the University of Leeds) and the general public health. The above listed training activities will be supplemented by a number of non-Technical skills for my career development. As a result of this cross-disciplinary project the fellow will be a well-rounded bioengineer researcher who in future will be become qualified for pursuing an academic career at the University of Leeds in the area of advanced drug delivery and photo-dynamic therapy using novel femtosecond lasers. Necessary research training and supervision at the UoL will be provided by the Engineering supervisor Prof. Animesh Jha (AJ) and the clinical supervisor Prof . Monty Duggal.

 Publications

year authors and title journal last update
List of publications.
2018 A.D. Anastasiou, S. Strafford, C.L. Thomson, J. Gardy, T.J. Edwards, M. Malinowski, S.A. Hussain, N.K. Metzger, A. Hassanpour, C.T.A. Brown, A.P. Brown, M.S. Duggal, A. Jha
Exogenous mineralization of hard tissues using photo-absorptive minerals and femto-second lasers; the case of dental enamel
published pages: , ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.02.012
Acta Biomaterialia 2019-06-18

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