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PRe-FActo

Periodontal Regeneration through Femtosecond laser Action

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 PRe-FActo project word cloud

Explore the words cloud of the PRe-FActo project. It provides you a very rough idea of what is the project "PRe-FActo" about.

ions    animesh    doped    tested    career    irradiation    lasers    supervisor    qualified    fellow    skills    collagen    cerium    leeds    aj    supplemented    beneficial    facto    am    femtosecond    potentially    jha    prof    fellowship    regenerative    sintered    pursuing    effect    host    deal    antibacterial    bioengineer    public    attachment    health    oxides    tests    ultrafast    laser    periodontium    material    erbium    aluminum    successful    academic    drug    prevention    histological    cell    dynamic    tooth    rounded    listed    global    cross    periodontitis    area    disease    training    mixed    photo    researcher    gel    engineering    densified    bonded    culture    therapy    outcome    synthesis    chitosan    uol    characterization    duggal    risks    disciplinary    clinical    topology    scientific    rtas    sintering    investigation    monty    fluoride    calcium    university    revival    supervision    pulsed    fibroblasts    say    toxicology    phosphates    surface    biomaterial    materials    intervened    exploring   

Project "PRe-FActo" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://aanastasiou83.wixsite.com/prefacto
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2017-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00

Map

 Project objective

The PRE-Facto fellowship aims to develop a new regenerative approach which potentially will promote the revival of the periodontium, while a successful outcome may lead also to the prevention of the disease when intervened early. Within my research I am going to develop a new biomaterial (calcium phosphates doped with ions of say, cerium and erbium oxides, fluoride and aluminum (3) ions) with antibacterial properties which will be densified and bonded on the tooth surface after the irradiation with an ultrafast pulsed laser (femtosecond laser). In order to promote the attachment of the fibroblasts, the biomaterial will be mixed with collagen gel (or chitosan) while the effect of the surface topology will be also tested. For my research training as a bioengineer within which I aim to solve periodontitis as a global problem I will deal with the following Research Training Activities (RTAs); i) Synthesis, characterization and delivery of the biomaterial; ii) Sintering of the materials with femtosecond laser - characterization of the sintered area; iii) Cell culture and histological studies for exploring the regenerative potential of the material; iv) Toxicology tests and potential risks investigation. This training is not only beneficial for the fellow’s scientific career development, but also for the host institute (the University of Leeds) and the general public health. The above listed training activities will be supplemented by a number of non-Technical skills for my career development. As a result of this cross-disciplinary project the fellow will be a well-rounded bioengineer researcher who in future will be become qualified for pursuing an academic career at the University of Leeds in the area of advanced drug delivery and photo-dynamic therapy using novel femtosecond lasers. Necessary research training and supervision at the UoL will be provided by the Engineering supervisor Prof. Animesh Jha (AJ) and the clinical supervisor Prof . Monty Duggal.

 Publications

year authors and title journal last update
List of publications.
2018 A.D. Anastasiou, S. Strafford, C.L. Thomson, J. Gardy, T.J. Edwards, M. Malinowski, S.A. Hussain, N.K. Metzger, A. Hassanpour, C.T.A. Brown, A.P. Brown, M.S. Duggal, A. Jha
Exogenous mineralization of hard tissues using photo-absorptive minerals and femto-second lasers; the case of dental enamel
published pages: , ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.02.012
Acta Biomaterialia 2019-06-18

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