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IDEM SIGNED

Immunity, DEvelopment and Microbiota: Understanding the Continuous Construction of Biological Identity

Total Cost €

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EC-Contrib. €

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Partnership

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Project "IDEM" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website https://www.immuconcept.org/erc-idem/
 Total cost 1˙454˙249 €
 EC max contribution 1˙454˙249 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-STG
 Funding Scheme ERC-STG
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙454˙249.00

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 Project objective

The problem of biological identity (what counts as one individual organism, and what makes each individual organism “the same” though it constantly changes through time?) has a long history both in philosophy and in science. Recent data coming from immunology, microbiology and developmental biology may revolutionize our conception of the construction of biological identity through time, by showing that this construction depends crucially on environmental factors and, most importantly, on a constant dialogue with symbiotic microorganisms integrated into the organism. IDEM, a fundamentally interdisciplinary project at the interface between philosophy and biology, aims at: i) determining to what extent it is adequate to see this shift as an ongoing “microbial revolution” in today’s biology; ii) understanding the exact processes by which developmental processes in organisms depend on microbial symbionts; iii) asking whether the role of the immune system (usually seen as a system that rejects genetically foreign elements from the body) in the maintenance of the organism needs to be reevaluated; iv) how traditional conceptions of biological individuality will be modified by this revolution. If funded, this project will provide a new understanding of the way living things are continuously constructed through time and interact with their biotic environment.

 Publications

year authors and title journal last update
List of publications.
2016 Thomas Pradeu, Gladys Kostyrka, John Dupré
Understanding viruses: Philosophical investigations
published pages: 57-63, ISSN: 1369-8486, DOI: 10.1016/j.shpsc.2016.02.008
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 59 2019-05-29
2017 Derek Skillings
Life is not easily bounded
published pages: , ISSN: , DOI:
Aeon (this magazine does not accept acknowledgments) 2019-05-29
2017 A. M. Ferner, Thomas Pradeu
Ontologies of Living Beings: Introduction
published pages: , ISSN: 2475-3025, DOI: 10.3998/ptb.6959004.0009.004
Philosophy, Theory, and Practice in Biology 9/20171201 2019-05-29
2018 Thomas Pradeu, Louis Du Pasquier
Immunological memory: What\'s in a name?
published pages: 7-20, ISSN: 0105-2896, DOI: 10.1111/imr.12652
Immunological Reviews 283/1 2019-05-29
2018 Alexandre Guay, Thomas Pradeu
Right out of the box: how to situate metaphysics of science in relation to other metaphysical approaches
published pages: , ISSN: 0039-7857, DOI: 10.1007/s11229-017-1576-8
Synthese 2019-05-29
2016 Thomas Pradeu, Eric Vivier
The discontinuity theory of immunity
published pages: aag0479-aag0479, ISSN: 2470-9468, DOI: 10.1126/sciimmunol.aag0479
Science Immunology 1/1 2019-05-29
2016 Thomas Pradeu
Organisms or biological individuals? Combining physiological and evolutionary individuality
published pages: 797-817, ISSN: 0169-3867, DOI: 10.1007/s10539-016-9551-1
Biology & Philosophy 31/6 2019-05-29
2016 Thomas Pradeu
The many faces of biological individuality
published pages: 761-773, ISSN: 0169-3867, DOI: 10.1007/s10539-016-9553-z
Biology & Philosophy 31/6 2019-05-29
2017 Lynn Chiu, Thomas Bazin, Marie-Elise Truchetet, Thierry Schaeverbeke, Laurence Delhaes, Thomas Pradeu
Protective Microbiota: From Localized to Long-Reaching Co-Immunity
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2017.01678
Frontiers in Immunology 8 2019-05-29
2018 Marie-Elise Truchetet, Thomas Pradeu
Re-thinking our understanding of immunity: Robustness in the tissue reconstruction system
published pages: 45-55, ISSN: 1044-5323, DOI: 10.1016/j.smim.2018.02.013
Seminars in Immunology 36 2019-05-29
2016 Thomas Pradeu
Mutualistic viruses and the heteronomy of life
published pages: 80-88, ISSN: 1369-8486, DOI: 10.1016/j.shpsc.2016.02.007
Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 59 2019-05-29
2017 Thomas Pradeu
Thirty years of Biology & Philosophy: philosophy of which biology?
published pages: 149-167, ISSN: 0169-3867, DOI: 10.1007/s10539-016-9558-7
Biology & Philosophy 32/2 2019-05-29
2018 Maureen A. O’Malley, Derek J. Skillings
Methodological Strategies in Microbiome Research and their Explanatory Implications
published pages: 239-265, ISSN: 1063-6145, DOI: 10.1162/POSC_a_00274
Perspectives on Science 26/2 2019-05-29
2017 Leonardo Bich, Sara Green
Is defining life pointless? Operational definitions at the frontiers of biology
published pages: , ISSN: 0039-7857, DOI: 10.1007/s11229-017-1397-9
Synthese 2019-05-29
2018 Gérard Eberl, Thomas Pradeu
Towards a General Theory of Immunity?
published pages: 261-263, ISSN: 1471-4906, DOI: 10.1016/j.it.2017.11.004
Trends in Immunology 39/4 2019-05-29
2017 Jean-Francois Moreau, Thomas Pradeu, Andrea Grignolio, Christine Nardini, Filippo Castiglione, Paolo Tieri, Miriam Capri, Stefano Salvioli, Jean-Luc Taupin, Paolo Garagnani, Claudio Franceschi
The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
published pages: 322-335, ISSN: 1568-1637, DOI: 10.1016/j.arr.2016.11.005
Ageing Research Reviews 35 2019-05-29
2016 Derek Skillings
Holobionts and the ecology of organisms: Multi-species communities or integrated individuals?
published pages: 875-892, ISSN: 0169-3867, DOI: 10.1007/s10539-016-9544-0
Biology & Philosophy 31/6 2019-05-29
2017 Paôline Laurent, Valérie Jolivel, Pauline Manicki, Lynn Chiu, Cécile Contin-Bordes, Marie-Elise Truchetet, Thomas Pradeu
Immune-Mediated Repair: A Matter of Plasticity
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2017.00454
Frontiers in Immunology 8 2019-05-29
2016 Lynn Chiu, Gérard Eberl
Microorganisms as scaffolds of host individuality: an eco-immunity account of the holobiont
published pages: 819-837, ISSN: 0169-3867, DOI: 10.1007/s10539-016-9552-0
Biology & Philosophy 31/6 2019-05-29

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