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3D-JOINT SIGNED
3D Bioprinting of JOINT Replacements
Total Cost €
0EC-Contrib. €
0Partnership
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03D-JOINT project word cloud
Explore the words cloud of the 3D-JOINT project. It provides you a very rough idea of what is the project "3D-JOINT" about.
repairing
biological
medical
hydrogel
regenerative
biomechanical
implants
focussed
printed
cell
replace
thermoplast
clinically
technologies
socio
organization
focal
reinforced
injured
screening
dimensional
living
therapy
deposition
limitation
successfully
hampered
joints
utrecht
ideal
composites
diameter
metal
tissue
burden
bioreactor
defects
synthetic
regenerate
invasive
pioneered
university
laboratory
degeneration
diseased
3d
phasic
injury
economic
world
filaments
form
center
combination
degenerated
placement
solution
small
regeneration
prosthesis
models
bio
replacement
holy
fibre
damaged
cells
provides
hydrogels
generation
resilience
smaller
grail
combines
accurately
cartilage
constructs
layer
albeit
decade
pain
larger
implanting
materials
printing
joint
lack
Project "3D-JOINT" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Organization address contact info |
| Coordinator Country | Netherlands [NL] |
| Total cost | 1˙998˙871 € |
| EC max contribution | 1˙998˙871 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2014-CoG |
| Funding Scheme | ERC-COG |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-07-01 to 2020-06-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITAIR MEDISCH CENTRUM UTRECHT | NL (UTRECHT) | coordinator | 1˙901˙871.00 |
| 2 | UNIVERSITEIT UTRECHT | NL (UTRECHT) | participant | 97˙000.00 |
Map
Project objective
The world has a significant medical challenge in repairing injured or diseased joints. Joint degeneration and its related pain is a major socio-economic burden that will increase over the next decade and is currently addressed by implanting a metal prosthesis. For the long term, the ideal solution to joint injury is to successfully regenerate rather than replace the damaged cartilage with synthetic implants. Recent advances in key technologies are now bringing this “holy grail” within reach; regenerative approaches, based on cell therapy, are already clinically available albeit only for smaller focal cartilage defects. One of these key technologies is three-dimensional (3D) bio-printing, which provides a greatly controlled placement and organization of living constructs through the layer-by-layer deposition of materials and cells. These tissue constructs can be applied as tissue models for research and screening. However, the lack of biomechanical properties of these tissue constructs has hampered their application to the regeneration of damaged, degenerated or diseased tissue.
Having established a cartilage-focussed research laboratory in the University Medical Center Utrecht, I have addressed this biomechanical limitation of hydrogels through the use of hydrogel composites. Specifically, I have pioneered a 3D bio-printing technology that combines accurately printed small diameter thermoplast filaments with cell invasive hydrogels to form strong fibre-reinforced constructs. This, in combination with bioreactor technology, is the key to the generation of larger, complex tissue constructs with cartilage-like biomechanical resilience. With 3D-JOINT I will use my in-depth bio-printing and bioreactor knowledge and experience to develop a multi-phasic 3D-printed biological replacement of the joint.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Paulina Nuñez Bernal, Paul Delrot, Damien Loterie, Yang Li, Jos Malda, Christophe Moser, Riccardo Levato Volumetric Bioprinting of Complex Livingâ€Tissue Constructs within Seconds published pages: 1904209, ISSN: 0935-9648, DOI: 10.1002/adma.201904209 |
Advanced Materials 31/42 | 2019-10-31 |
| 2019 |
Marleen Kristen, Madison J. Ainsworth, Nino Chirico, Casper F. T. Ven, Pieter A. Doevendans, Joost P. G. Sluijter, Jos Malda, Alain Mil, Miguel Castilho Fiber Scaffold Patterning for Mending Hearts: 3D Organization Bringing the Next Step published pages: 1900775, ISSN: 2192-2640, DOI: 10.1002/adhm.201900775 |
Advanced Healthcare Materials | 2019-10-31 |
| 2019 |
Mylène de Ruijter, Alexandre Ribeiro, Inge Dokter, Miguel Castilho, Jos Malda Simultaneous Micropatterning of Fibrous Meshes and Bioinks for the Fabrication of Living Tissue Constructs published pages: 1800418, ISSN: 2192-2640, DOI: 10.1002/adhm.201800418 |
Advanced Healthcare Materials 8/7 | 2019-10-29 |
| 2019 |
I.A.D. Mancini, L. Rieppo, B. Pouran, I.O. Afara, F.M. Serra Braganca, M.H.P. van Rijen, M. Kik, H. Weinans, J. Toyras, P.R. van Weeren, J. Malda Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species published pages: 664-673, ISSN: 8756-3282, DOI: 10.1016/j.bone.2019.07.001 |
Bone 127 | 2019-10-29 |
| 2019 |
Miguel Castilho, Vivian Mouser, Mike Chen, Jos Malda, Keita Ito Bi-layered micro-fibre reinforced hydrogels for articular cartilage regeneration published pages: 297-306, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2019.06.030 |
Acta Biomaterialia 95 | 2019-10-29 |
| 2018 |
Lorenzo Moroni, Thomas Boland, Jason A. Burdick, Carmelo De Maria, Brian Derby, Gabor Forgacs, Jürgen Groll, Qing Li, Jos Malda, Vladimir A. Mironov, Carlos Mota, Makoto Nakamura, Wenmiao Shu, Shoji Takeuchi, Tim B.F. Woodfield, Tao Xu, James J. Yoo, Giovanni Vozzi Biofabrication: A Guide to Technology and Terminology published pages: 384-402, ISSN: 0167-7799, DOI: 10.1016/j.tibtech.2017.10.015 |
Trends in Biotechnology 36/4 | 2019-10-29 |
| 2018 |
Katja Jansen, Miguel Castilho, Sanne Aarts, Michael M. Kaminski, Soeren S. Lienkamp, Roman Pichler, Jos Malda, Tina Vermonden, Jitske Jansen, Rosalinde Masereeuw Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds published pages: 1800412, ISSN: 1616-5187, DOI: 10.1002/mabi.201800412 |
Macromolecular Bioscience 19/2 | 2019-10-29 |
| 2018 |
Vivian Mouser Ex vivo model unravelling cell distribution effect in hydrogels for cartilage repair published pages: 65-76, ISSN: 1868-596X, DOI: 10.14573/altex.1704171 |
ALTEX | 2019-10-29 |
| 2019 |
Jos Malda, Jürgen Groll, P. René van Weeren Rethinking articular cartilage regeneration based on a 250-year-old statement published pages: 571-572, ISSN: 1759-4790, DOI: 10.1038/s41584-019-0278-7 |
Nature Reviews Rheumatology 15/10 | 2019-10-29 |
| 2019 |
J. Boere, C.H.A. van de Lest, J.C. de Grauw, S.G.M. Plomp, S.F.W.M. Libregts, G.J.A. Arkesteijn, J. Malda, M.H.M. Wauben, P.R. van Weeren Extracellular vesicles in synovial fluid from juvenile horses: No age-related changes in the quantitative profile published pages: 91-93, ISSN: 1090-0233, DOI: 10.1016/j.tvjl.2018.12.010 |
The Veterinary Journal 244 | 2019-10-29 |
| 2018 |
Marcia de Almeida Monteiro Melo Ferraz, Heiko H. W. Henning, Pedro Ferreira da Costa, Jos Malda, Séverine Le Gac, Fabrice Bray, Majorie B. M. van Duursen, Jos F. Brouwers, Chris H. A. van de Lest, Ingeborg Bertijn, Lisa Kraneburg, Peter L. A. M. Vos, Tom A. E. Stout, Barend M. Gadella Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers published pages: 80-85, ISSN: 2328-8930, DOI: 10.1021/acs.estlett.7b00495 |
Environmental Science & Technology Letters 5/2 | 2019-10-29 |
| 2018 |
Janneke Boere, Jos Malda, Chris H. A. van de Lest, P. René van Weeren, Marca H. M. Wauben Extracellular Vesicles in Joint Disease and Therapy published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.02575 |
Frontiers in Immunology 9 | 2019-10-29 |
| 2018 |
Jaakko K. Sarin, Nikae C. R. te Moller, Irina A. D. Mancini, Harold Brommer, Jetze Visser, Jos Malda, P. René van Weeren, Isaac O. Afara, Juha Töyräs Arthroscopic near infrared spectroscopy enables simultaneous quantitative evaluation of articular cartilage and subchondral bone in vivo published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-31670-5 |
Scientific Reports 8/1 | 2019-10-29 |
| 2019 |
J Groll, J A Burdick, D-W Cho, B Derby, M Gelinsky, S C Heilshorn, T Jüngst, J Malda, V A Mironov, K Nakayama, A Ovsianikov, W Sun, S Takeuchi, J J Yoo, T B F Woodfield A definition of bioinks and their distinction from biomaterial inks published pages: 13001, ISSN: 1758-5090, DOI: 10.1088/1758-5090/aaec52 |
Biofabrication 11/1 | 2019-10-29 |
| 2019 |
Barbara J. Klotz, Loes A. Oosterhoff, Lizette Utomo, Khoon S. Lim, Queralt Vallmajoâ€Martin, Hans Clevers, Tim B. F. Woodfield, Antoine J. W. P. Rosenberg, Jos Malda, Martin Ehrbar, Bart Spee, Debby Gawlitta A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues published pages: 1900979, ISSN: 2192-2640, DOI: 10.1002/adhm.201900979 |
Advanced Healthcare Materials 8/19 | 2019-10-29 |
| 2017 |
Miguel Castilho, Dries Feyen, MarÃa Flandes-Iparraguirre, Gernot Hochleitner, Jürgen Groll, Pieter A. F. Doevendans, Tina Vermonden, Keita Ito, Joost P. G. Sluijter, Jos Malda Melt Electrospinning Writing of Poly-Hydroxymethylglycolide- co -ε-Caprolactone-Based Scaffolds for Cardiac Tissue Engineering published pages: 1700311, ISSN: 2192-2640, DOI: 10.1002/adhm.201700311 |
Advanced Healthcare Materials 6/18 | 2019-06-06 |
| 2016 |
Zita M. Jessop, Muhammad Javed, Iris A. Otto, Emman J. Combellack, Siân Morgan, Corstiaan C. Breugem, Charles W. Archer, Ilyas M. Khan, William C. Lineaweaver, Moshe Kon, Jos Malda, Iain S. Whitaker Combining regenerative medicine strategies to provide durable reconstructive options: auricular cartilage tissue engineering published pages: 7/19, ISSN: 1757-6512, DOI: 10.1186/s13287-015-0273-0 |
Stem Cell Research & Therapy 7/1 | 2019-06-06 |
| 2016 |
I A Otto, C C Breugem, J Malda, A L Bredenoord Ethical considerations in the translation of regenerative biofabrication technologies into clinic and society published pages: 42001, ISSN: 1758-5090, DOI: 10.1088/1758-5090/8/4/042001 |
Biofabrication 8/4 | 2019-06-06 |
| 2017 |
his piece was produced by Science Impact Joint endeavours published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2015 |
J. Visser, R. J. Custers, P. D. Dalton, R. Nizak, D. B.F. Saris, D. Gawlitta, J. Malda Biofabrication of anatomically shaped implants for regeneration of the rabbit humeral head published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
Anna Abbadessa, Vivian H. M. Mouser, Maarten M. Blokzijl, Debby Gawlitta, Wouter J. A. Dhert, Wim E. Hennink, Jos Malda, Tina Vermonden A Synthetic Thermosensitive Hydrogel for Cartilage Bioprinting and Its Biofunctionalization with Polysaccharides published pages: 2137-2147, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.6b00366 |
Biomacromolecules 17/6 | 2019-06-06 |
| 2017 |
C. Villete, M. Castilho, J. Malda, A. Philips Optimization of Heterogeneous Bone Tissue Engineering Scaffolds: Proof of Concept for a digital design tool. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
Vivian H M Mouser, Ferry P W Melchels, Jetze Visser, Wouter J A Dhert, Debby Gawlitta, Jos Malda Yield stress determines bioprintability of hydrogels based on gelatin-methacryloyl and gellan gum for cartilage bioprinting published pages: 35003, ISSN: 1758-5090, DOI: 10.1088/1758-5090/8/3/035003 |
Biofabrication 8/3 | 2019-06-06 |
| 2016 |
M. de Ruijter, A. Hrynevich, J.N. Haigh, M. Castilho, G. Hochleitner, J. Groll, J Malda, and P.D. Dalton Melt electrospun fibers to improve shear properties published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
R. Levato, W.R. Webb, I.A. Otto IA, V.H.M. Mouser, P.R. van Weeren, I.M. Khan, J. Malda The bio in the ink: zonal-competent progenitor cells in printed layered constructs for cartilage regeneration published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
Kerstin Schneeberger, Bart Spee, Pedro Costa, Norman Sachs, Hans Clevers, Jos Malda Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? published pages: 13001, ISSN: 1758-5090, DOI: 10.1088/1758-5090/aa6121 |
Biofabrication 9/1 | 2019-06-06 |
| 2017 |
M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda Converging of melt electrospinning writing and extrusion based bioprinting for cartilage tissue regeneration. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
M. de Ruijter, A. Hrynevich, J.N. Haigh, G. Hochleitner, M. Castilho, J. Malda 3D-Microfibers improve the shear modulus of hydrogel composites. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
C. Villete, M. Castilho, J. Malda, A. Philips Optimised heterogeneous scaffolds: towards tailored bone mechanotransduction. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
Jos Malda, Janneke Boere, Chris H. A. van de Lest, P. René van Weeren, Marca H. M. Wauben Extracellular vesicles — new tool for joint repair and regeneration published pages: 243-249, ISSN: 1759-4790, DOI: 10.1038/nrrheum.2015.170 |
Nature Reviews Rheumatology 12/4 | 2019-06-06 |
| 2016 |
A. Abbadessa, M.M. Blokzijl, V.H.M. Mouser, P. Marica, J. Malda, W.E. Hennink, T. Vermonden A thermo-responsive and photo-polymerizable chondroitin sulfate-based hydrogel for 3D printing applications published pages: 163-174, ISSN: 0144-8617, DOI: 10.1016/j.carbpol.2016.04.080 |
Carbohydrate Polymers 149 | 2019-06-06 |
| 2016 |
M. de Ruijter, F.P.W Melchels, R. Levato, J. Malda Hydrogel encapsulation and Micro-aggregation of co-culture MSC/AC for tissue regeneration. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
Riccardo Levato, William R. Webb, Iris A. Otto, Anneloes Mensinga, Yadan Zhang, Mattie van Rijen, René van Weeren, Ilyas M. Khan, Jos Malda The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells published pages: 41-53, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2017.08.005 |
Acta Biomaterialia 61 | 2019-06-06 |
| 2017 |
R.A. Vindas Bolaños, S.M. Cokelaere, J.M. Estrada McDermott, K.E.M. Benders, U. Gbureck, S.G.M. Plomp, H. Weinans, J. Groll, P.R. van Weeren, J. Malda The use of a cartilage decellularized matrix scaffold for the repair of osteochondral defects: the importance of long-term studies in a large animal model published pages: 413-420, ISSN: 1063-4584, DOI: 10.1016/j.joca.2016.08.005 |
Osteoarthritis and Cartilage 25/3 | 2019-06-06 |
| 2017 |
M. Castilho, C. Moseke, U.Gbureck, E. Vorndran 3D printing of osteoconductive patient-specific bone implants. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
M. Castilho, G. Hochleitner, W. Wilson, J. Groll, J. Malda, K. Ito Mechanical behaviour of soft hydrogels reinforced with printed microfiber scaffolds for cartilage repair. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
Pedro F. Costa, Hugo J. Albers, John E. A. Linssen, Heleen H. T. Middelkamp, Linda van der Hout, Robert Passier, Albert van den Berg, Jos Malda, Andries D. van der Meer Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data published pages: 2785-2792, ISSN: 1473-0197, DOI: 10.1039/c7lc00202e |
Lab Chip 17/16 | 2019-06-06 |
| 2017 |
Wilhelmina Margaretha Groen, Paweena Diloksumpan, Paul René van Weeren, Riccardo Levato, Jos Malda From intricate to integrated: Biofabrication of articulating joints published pages: 2089-2097, ISSN: 0736-0266, DOI: 10.1002/jor.23602 |
Journal of Orthopaedic Research 35/10 | 2019-06-06 |
| 2015 |
Kristel W. M. Boere, Maarten M. Blokzijl, Jetze Visser, J. Elder A. Linssen, Jos Malda, Wim E. Hennink, Tina Vermonden Biofabrication of reinforced 3D-scaffolds using two-component hydrogels published pages: 9067-9078, ISSN: 2050-7518, DOI: 10.1039/c5tb01645b |
Journal of Materials Chemistry B 3/46 | 2019-06-06 |
| 2016 |
K.S. Lim, R. Levato, P.F. Costa, M.D. Castilho, K. van Dorenmalen, F.P.W. Melchel, D. Gawlitta, J. Malda , T.B.F. Woodfield Biofunctional and complex hydrogel architectures fabricated via visible light photo-crosslinking with digital light processing. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
M. Castilho, S. Kogelenberg, V. Mouser, J. Malda, K. Ito Improving mechanical functioning of micro-fibre reinforced hydrogels for zonal articular cartilage repair. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2018 |
A Ribeiro, M M Blokzijl, R Levato, C W Visser, M Castilho, W E Hennink, T Vermonden, J Malda Assessing bioink shape fidelity to aid material development in 3D bioprinting published pages: 14102, ISSN: 1758-5090, DOI: 10.1088/1758-5090/aa90e2 |
Biofabrication 10/1 | 2019-06-06 |
| 2017 |
M. Castilho, S. van Kogelenberg, J. Malda, K. Ito Improving mechanical functioning of micro-fibre reinforced hydrogels for cartilage repair. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
A. Ribeiro, M. Blokzijl, R. Levato, M. Castilho, W. Hennink, T. Vermonden, J. Malda Assessing bioink printability with accessible and quantitative methods. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
M. Castilho, D. Feyen, M. Flandes-Iparraguirre, G. Hochleitner, P. Dalton, J. Groll, T. Vermonden, J. Malda, J. Sluijter Melt electrospinning writing of poly-hydroxymethylglycolide-co-ε-caprolactone-based scaffolds for cardiac tissue engineering. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
Irina A.D. Mancini, Rafael A. Vindas Bolaños, Harold Brommer, Miguel Castilho, Alexandro Ribeiro, Johannes P.A.M. van Loon, Anneloes Mensinga, Mattie H.P. van Rijen, Jos Malda, René van Weeren Fixation of Hydrogel Constructs for Cartilage Repair in the Equine Model: A Challenging Issue published pages: 804-814, ISSN: 1937-3384, DOI: 10.1089/ten.TEC.2017.0200 |
Tissue Engineering Part C: Methods 23/11 | 2019-06-06 |
| 2017 |
Mylène de Ruijter, Andrei Hrynevich, Jodie N. Haigh, Gernot Hochleitner, Miguel Castilho, Jürgen Groll, Jos Malda, Paul D. Dalton Out-of-Plane 3D-Printed Microfibers Improve the Shear Properties of Hydrogel Composites published pages: 1702773, ISSN: 1613-6810, DOI: 10.1002/smll.201702773 |
Small | 2019-06-06 |
| 2016 |
Vivian H. M. Mouser, Riccardo Levato, Lawrence J. Bonassar, Darryl D. D’Lima, Daniel A. Grande, Travis J. Klein, Daniel B. F. Saris, Marcy Zenobi-Wong, Debby Gawlitta, Jos Malda Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration published pages: 327-340, ISSN: 1947-6035, DOI: 10.1177/1947603516665445 |
CARTILAGE 8/4 | 2019-06-06 |
| 2017 |
R. Levato, V. Mouser, W. Dhert, D. Gawlitta, R. van Weeren, J. Malda Bioink development and role of cell-bioink interaction for the biofabrication. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
P. Diloksumpan, M. Castilho, T. Vermonden, R. van Weeren, J. Malda, R. Levato Reinforcing hydrogel-to-ceramic interface in osteochondral constructs by converging additive manufacturing techniques. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
M. de Ruijter, A. Ribeiro, I. Dokter, M. Castilho, J. Malda Converging MEW and extrusion-based bioprinting enables further mimicking of complex tissue architectures. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2017 |
M. Blokzijl, A. Ribeiro, C. Visser, R. Levato, M. Castilho, W. Hennink, T. Vermonden, J. Malda Approach for standardized evaluation of printability and structural deformation of extruded bioink filaments. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
Ferry P W Melchels, Maarten M Blokzijl, Riccardo Levato, Quentin C Peiffer, Mylène de Ruijter, Wim E Hennink, Tina Vermonden, Jos Malda Hydrogel-based reinforcement of 3D bioprinted constructs published pages: 35004, ISSN: 1758-5090, DOI: 10.1088/1758-5090/8/3/035004 |
Biofabrication 8/3 | 2019-06-06 |
| 2016 |
Barbara J. Klotz, Debby Gawlitta, Antoine J.W.P. Rosenberg, Jos Malda, Ferry P.W. Melchels Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair published pages: 394-407, ISSN: 0167-7799, DOI: 10.1016/j.tibtech.2016.01.002 |
Trends in Biotechnology 34/5 | 2019-06-06 |
| 2017 |
R. Levato, I.A. Otto, W.R. Webb, R. Van Weeren, I.M. Khan, J. Malda Application of different cell populations in hydrogel bioinks for zonal cartilage biofabrication. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2015 |
J. Visser, F. Melchels, I. Mancini, H. Brommer, P.Dalton, W.r Dhert, D. Saris, D. Hutmacher, R. van Weeren, J. Malda Reinforced gelatin hydrogels for cartilage repair: from in vitro testing to implantation in the equine knee joint. published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2016 |
F.P.W Melchels, K.E.C. Blokland, M. de Ruijter, J. Malda A dual crosslinking strategy for reinforcing gelatine-methacrylamide hydrogels for tissue repair published pages: , ISSN: , DOI: |
2019-06-06 | |
| 2018 |
Miguel Castilho, Gernot Hochleitner, Wouter Wilson, Bert van Rietbergen, Paul D. Dalton, Jürgen Groll, Jos Malda, Keita Ito Mechanical behavior of a soft hydrogel reinforced with three-dimensional printed microfibre scaffolds published pages: 1245, ISSN: 2045-2322, DOI: 10.1038/s41598-018-19502-y |
Scientific Reports 8/1 | 2019-06-06 |
| 2017 |
V H M Mouser, A Abbadessa, R Levato, W E Hennink, T Vermonden, D Gawlitta, J Malda Development of a thermosensitive HAMA-containing bio-ink for the fabrication of composite cartilage repair constructs published pages: 15026, ISSN: 1758-5090, DOI: 10.1088/1758-5090/aa6265 |
Biofabrication 9/1 | 2019-06-06 |
| 2017 |
M. de Ruijter, A. Hrynevich, J.N. Haigh, M. Castilho, G. Hochleitner, J. Groll, J Malda, and P.D. Dalton Fabricatie van microvezels ter versterking van hydrogelen voor regeneratie van kraakbeen. published pages: , ISSN: , DOI: |
2019-06-06 |
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