Explore the words cloud of the ENLIGHT-TEN project. It provides you a very rough idea of what is the project "ENLIGHT-TEN" about.
The following table provides information about the project.
Coordinator |
HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Organization address contact info |
Coordinator Country | Germany [DE] |
Project website | http://www.enlight-ten.eu |
Total cost | 3˙354˙685 € |
EC max contribution | 3˙354˙685 € (100%) |
Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
Code Call | H2020-MSCA-ITN-2015 |
Funding Scheme | MSCA-ITN-ETN |
Starting year | 2015 |
Duration (year-month-day) | from 2015-10-01 to 2019-09-30 |
Take a look of project's partnership.
ENLIGHT-TEN is a European Network Linking Informatics and Genomics of Helper T cells: our mission is to provide cross-disciplinary training in cellular immunology and big data analysis such that we train a new generation of researchers to fully exploit the power of emerging technological platforms. Our network of TEN beneficiaries combines T cell expertise with state-of-the-art technologies such as next generation sequencing (NGS), bioinformatics, multi-colour flow cytometry, preclinical models and tailored genome editing. Trainees will acquire a comprehensive knowledge in T cell immunology and the capacity to generate and interrogate big data sets as well as expertise in identifying novel biomarkers and developing therapeutic concepts. As such the training programme will provide an ideal stepping-stone for creative and innovative early stage researchers (ESRs) to enter and strengthen Europe’s academia as well as pharmaceutical and bioinformatics companies. The research focus of the network lies in the identification of extrinsic and intrinsic factors that control development, differentiation and plasticity of helper T cell subsets with particular emphasis on how T cell differentiation impacts on human diseases. The generation of large data sets is an emerging and challenging field, and there is high demand in both the academic sector as well as pharmaceutical companies for researchers to be able to analyse, integrate and exploit this rich source of information. ENLIGHT-TEN will combine the individual strengths of innovative laboratories and enterprises from complementary disciplines to provide unique interdisciplinary training for 13 ESRs, placing them at the forefront of this emerging field. Trainees will be empowered to perform cutting-edge analysis of the steadily increasing number of different T cell subsets, which play highly diverse and critical roles in the development of autoimmune diseases, making them a key target for pharmaceutical companies.
Midterm review meeting | Other | 2020-04-07 20:07:59 |
Take a look to the deliverables list in detail: detailed list of ENLIGHT-TEN deliverables.
year | authors and title | journal | last update |
---|---|---|---|
2020 |
Yi-Ling Chen, Tomas Gomes, Clare S. Hardman, Felipe A. Vieira Braga, Danuta Gutowska-Owsiak, Maryam Salimi, Nicki Gray, David A. Duncan, Gary Reynolds, David Johnson, Mariolina Salio, Vincenzo Cerundolo, Jillian L. Barlow, Andrew N.J. McKenzie, Sarah A. Teichmann, Muzlifah Haniffa, Graham Ogg Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation published pages: , ISSN: 0022-1007, DOI: 10.1084/jem.20190811 |
The Journal of Experimental Medicine 217/3 | 2020-04-07 |
2019 |
Tomás Gomes, Sarah A. Teichmann, Carlos Talavera-López Immunology Driven by Large-Scale Single-Cell Sequencing published pages: 1011-1021, ISSN: 1471-4906, DOI: 10.1016/j.it.2019.09.004 |
Trends in Immunology 40/11 | 2020-04-07 |
2018 |
Daniel J. Kunz, Tomás Gomes, Kylie R. James Immune Cell Dynamics Unfolded by Single-Cell Technologies published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.01435 |
Frontiers in Immunology 9 | 2020-04-07 |
2018 |
Ekaterina Minskaia, Barbara C. Saraiva, Maria M. V. Soares, Rita I. Azevedo, Ruy M. Ribeiro, Saumya D. Kumar, Ana I. S. Vieira, João F. Lacerda Molecular Markers Distinguishing T Cell Subtypes With TSDR Strand-Bias Methylation published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.02540 |
Frontiers in Immunology 9 | 2020-04-07 |
2018 |
Lina Petersone, Natalie M. Edner, Vitalijs Ovcinnikovs, Frank Heuts, Ellen M. Ross, Elisavet Ntavli, Chun J. Wang, Lucy S. K. Walker T Cell/B Cell Collaboration and Autoimmunity: An Intimate Relationship published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.01941 |
Frontiers in Immunology 9 | 2020-04-07 |
2019 |
Thomas Faux, Kalle T. Rytkönen, Asta Laiho, Laura L. Elo RepViz: a replicate-driven R tool for visualizing genomic regions published pages: , ISSN: 1756-0500, DOI: 10.1186/s13104-019-4473-z |
BMC Research Notes 12/1 | 2020-04-07 |
2018 |
Marisa Stebegg, Saumya D. Kumar, Alyssa Silva-Cayetano, Valter R. Fonseca, Michelle A. Linterman, Luis Graca Regulation of the Germinal Center Response published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.02469 |
Frontiers in Immunology 9 | 2020-04-07 |
2018 |
Jhuma Pramanik, Xi Chen, Gozde Kar, Johan Henriksson, Tomás Gomes, Jong-Eun Park, Kedar Natarajan, Kerstin B. Meyer, Zhichao Miao, Andrew N. J. McKenzie, Bidesh Mahata, Sarah A. Teichmann Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation published pages: , ISSN: 1756-994X, DOI: 10.1186/s13073-018-0589-3 |
Genome Medicine 10/1 | 2020-04-07 |
2017 |
Tomi Suomi, Fatemeh Seyednasrollah, Maria K. Jaakkola, Thomas Faux, Laura L. Elo ROTS: An R package for reproducibility-optimized statistical testing published pages: e1005562, ISSN: 1553-7358, DOI: 10.1371/journal.pcbi.1005562 |
PLOS Computational Biology 13/5 | 2020-04-07 |
2017 |
Verena Brucklacher-Waldert, Cristina Ferreira, Marisa Stebegg, Olivier Fesneau, Silvia Innocentin, Julien C. Marie, Marc Veldhoen Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation published pages: 2357-2370, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2017.05.052 |
Cell Reports 19/11 | 2020-04-07 |
2019 |
Marisa Stebegg, Alyssa Silva-Cayetano, Silvia Innocentin, Timothy P. Jenkins, Cinzia Cantacessi, Colin Gilbert, Michelle A. Linterman Heterochronic faecal transplantation boosts gut germinal centres in aged mice published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-10430-7 |
Nature Communications 10/1 | 2020-04-07 |
2019 |
Vitalijs Ovcinnikovs, Ellen M. Ross, Lina Petersone, Natalie M. Edner, Frank Heuts, Elisavet Ntavli, Alexandros Kogimtzis, Alan Kennedy, Chun Jing Wang, Clare L. Bennett, David M. Sansom, Lucy S. K. Walker CTLA-4–mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells published pages: eaaw0902, ISSN: 2470-9468, DOI: 10.1126/sciimmunol.aaw0902 |
Science Immunology 4/35 | 2020-04-07 |
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The information about "ENLIGHT-TEN" are provided by the European Opendata Portal: CORDIS opendata.