#	Pagina
attuale pagina	/open-h2020/projects/198410/index.html
-1	/open-h2020/projects/208154/index.html

Opendata, web and dolomites

IonoChem

IonoChem: A new and highly efficient cross membrane drug delivery strategy

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

IonoChem project word cloud

Explore the words cloud of the IonoChem project. It provides you a very rough idea of what is the project "IonoChem" about.

worth 11 establishment nature clients 2013 contract lipophilization solution platform manufacturer sufficient facilities gmp therapeutics head techniques toxic initial annual technologies company systemic perform eg contact turn segments membrane drugs customer inside elaboration ionochem times ionovation withdrawn vioxx proprietary refinement enter preclinical designed manufacturers intracellular search pass tail setting drug upscaling sales valued one patient fee cells customers market quantities 151 suitable model global business membranes us lipohilic amounts rnai ratio molecules easily experimental dna types biological many classes administered ups adding tails introduction line plan molecule cell licensing vs qualification hydrophobic service pricing quarters billion rna

Project "IonoChem" data sheet

The following table provides information about the project.

Coordinator	IONOVATION GMBH Organization address address: WESTERBREITE 7 city: OSNABRUCK postcode: 49084 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Project website	http://www.ionovation.com/index.php/ionochem
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument) 2. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
Code Call	H2020-SMEINST-1-2015
Funding Scheme	SME-1
Starting year	2015
Duration (year-month-day)	from 2015-09-01 to 2016-02-29

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	IONOVATION GMBH IONOVATION GMBH Organization address address: WESTERBREITE 7 city: OSNABRUCK postcode: 49084 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (OSNABRUCK)	coordinator	50˙000.00

Map

Project objective

Many drugs are designed to target molecules inside cells. Due to the hydrophobic nature of the cell membranes however not all types of drugs can enter the cells in sufficient quantities. Thus large amounts of drug need to be administered which can lead to highly toxic systemic effects for the patient. Furthermore, new classes of therapeutics such as RNA- and DNA-based drugs require advanced delivery techniques to reach their intracellular targets. Ionovation’s proprietary IonoChem technology will provide a novel and highly effective solution to this problem by adding lipohilic “tails” directly to drug molecules at a one-on-one ratio. These “tails” allow drugs to easily pass through the cell membrane. As part of a service offer Ionovation will work with clients to identify the most effective tail for a particular molecule, and will also perform the lipophilization. The IonoChem platform will enable Ionovation GmbH (a manufacturer of experimental set-ups for the analysis of biological membranes) to enter the market for drug delivery technologies, thus creating a new line of business for the company. IonoChem will target the market for drug delivery systems, which was valued at US$151 billion in 2013. Market segments for initial introduction of the technology include RNAi drug delivery (a market worth US $11,7 billion in 2013) and drugs withdrawn from the market (eg Vioxx with 2.5 billion US $ annual global sales). Objectives of the phase I project include analysis of customer needs (pricing, expected turn-around times etc.), refinement of business model (licensing/fee for use model for contract manufacturers vs. service offer with production facilities at Ionovation’s head quarters); search for a suitable contract manufacturer for the phase II activities and the elaboration of a business plan. Phase II objectives include upscaling of the production under GMP conditions, establishment of contact to customers and the qualification of IonoChem in a preclinical setting.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "IONOCHEM" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "IONOCHEM" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.2.3.1.;H2020-EU.2.1.2.)

S3D (2015)

Feasibility study to determine the use of ITS technology to replace nuclear density meters in mining, dredging and other areas of hydraulic transport.