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IonoChem

IonoChem: A new and highly efficient cross membrane drug delivery strategy

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

IonoChem project word cloud

Explore the words cloud of the IonoChem project. It provides you a very rough idea of what is the project "IonoChem" about.

molecules annual perform administered gmp refinement easily adding toxic suitable ionovation therapeutics eg solution types valued turn biological fee drugs technologies clients customer pricing establishment introduction techniques 2013 amounts inside lipohilic one contact model ups 11 experimental membranes global hydrophobic preclinical facilities vs tails many nature customers upscaling designed 151 manufacturer proprietary contract market rnai lipophilization systemic sufficient pass vioxx business manufacturers sales quarters enter company dna tail worth qualification setting intracellular licensing times ratio billion head plan line classes search cell initial drug segments withdrawn platform ionochem quantities patient molecule elaboration service cells rna us membrane

Project "IonoChem" data sheet

The following table provides information about the project.

Coordinator	IONOVATION GMBH Organization address address: WESTERBREITE 7 city: OSNABRUCK postcode: 49084 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Project website	http://www.ionovation.com/index.php/ionochem
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument) 2. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
Code Call	H2020-SMEINST-1-2015
Funding Scheme	SME-1
Starting year	2015
Duration (year-month-day)	from 2015-09-01 to 2016-02-29

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	IONOVATION GMBH IONOVATION GMBH Organization address address: WESTERBREITE 7 city: OSNABRUCK postcode: 49084 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (OSNABRUCK)	coordinator	50˙000.00

Map

Project objective

Many drugs are designed to target molecules inside cells. Due to the hydrophobic nature of the cell membranes however not all types of drugs can enter the cells in sufficient quantities. Thus large amounts of drug need to be administered which can lead to highly toxic systemic effects for the patient. Furthermore, new classes of therapeutics such as RNA- and DNA-based drugs require advanced delivery techniques to reach their intracellular targets. Ionovation’s proprietary IonoChem technology will provide a novel and highly effective solution to this problem by adding lipohilic “tails” directly to drug molecules at a one-on-one ratio. These “tails” allow drugs to easily pass through the cell membrane. As part of a service offer Ionovation will work with clients to identify the most effective tail for a particular molecule, and will also perform the lipophilization. The IonoChem platform will enable Ionovation GmbH (a manufacturer of experimental set-ups for the analysis of biological membranes) to enter the market for drug delivery technologies, thus creating a new line of business for the company. IonoChem will target the market for drug delivery systems, which was valued at US$151 billion in 2013. Market segments for initial introduction of the technology include RNAi drug delivery (a market worth US $11,7 billion in 2013) and drugs withdrawn from the market (eg Vioxx with 2.5 billion US $ annual global sales). Objectives of the phase I project include analysis of customer needs (pricing, expected turn-around times etc.), refinement of business model (licensing/fee for use model for contract manufacturers vs. service offer with production facilities at Ionovation’s head quarters); search for a suitable contract manufacturer for the phase II activities and the elaboration of a business plan. Phase II objectives include upscaling of the production under GMP conditions, establishment of contact to customers and the qualification of IonoChem in a preclinical setting.

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The information about "IONOCHEM" are provided by the European Opendata Portal: CORDIS opendata.

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