Explore the words cloud of the MicrobioS project. It provides you a very rough idea of what is the project "MicrobioS" about.
The following table provides information about the project.
Coordinator |
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Organization address contact info |
Coordinator Country | Germany [DE] |
Total cost | 2˙184˙432 € |
EC max contribution | 2˙184˙432 € (100%) |
Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
Code Call | ERC-2014-ADG |
Funding Scheme | ERC-ADG |
Starting year | 2016 |
Duration (year-month-day) | from 2016-07-01 to 2021-06-30 |
Take a look of project's partnership.
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1 | EUROPEAN MOLECULAR BIOLOGY LABORATORY | DE (HEIDELBERG) | coordinator | 2˙184˙432.00 |
With the genome sequencing of hundreds of bacterial isolates per day and a vast and growing number of metagenomic sequencing projects on gut microbiomes in healthy and diseased people all over the world, it becomes feasible to explore the microbial diversity in us not only at the level of genera and species, but at strains. As two different strains of a prokaryotic species might only share 40% of the genes and can also have vastly differ in single nucleotide polymorphism (SNP) many aspects of a proper understanding of the microbial communities we host in the gut might only be revealed at this high resolution level. This proposal aims (i) to develop a robust methodology to characterize the SNP and gene content landscape from metagenomic shotgun data (ii) to explore patterns of variation in the human population to stratify geographically, but also in subpopulations such as families and to understand spreading patterns and the evolution of microbial strains as well as iii) to work towards medical applications, for example by monitoring fecal microbiota transplantation (FMT) at strain resolution or monitoring particular strain of interest in the population
year | authors and title | journal | last update |
---|---|---|---|
2017 |
Paul I Costea, Luis Pedro Coelho, Shinichi Sunagawa, Robin Munch, Jaime Huertaâ€Cepas, Kristoffer Forslund, Falk Hildebrand, Almagul Kushugulova, Georg Zeller, Peer Bork Subspecies in the global human gut microbiome published pages: 960, ISSN: 1744-4292, DOI: 10.15252/msb.20177589 |
Molecular Systems Biology 13/12 | 2019-07-04 |
2017 |
J. R. Bedarf, F. Hildebrand, L. P. Coelho, S. Sunagawa, M. Bahram, F. Goeser, P. Bork, U. Wüllner Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients published pages: , ISSN: 1756-994X, DOI: 10.1186/s13073-017-0428-y |
Genome Medicine 9/1 | 2019-07-04 |
2017 |
Jaime Huerta-Cepas, Kristoffer Forslund, Luis Pedro Coelho, Damian Szklarczyk, Lars Juhl Jensen, Christian von Mering, Peer Bork Fast Genome-Wide Functional Annotation through Orthology Assignment by eggNOG-Mapper published pages: 2115-2122, ISSN: 0737-4038, DOI: 10.1093/molbev/msx148 |
Molecular Biology and Evolution 34/8 | 2019-07-04 |
2017 |
Paul Igor Costea, Robin Munch, Luis Pedro Coelho, Lucas Paoli, Shinichi Sunagawa, Peer Bork metaSNV: A tool for metagenomic strain level analysis published pages: e0182392, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0182392 |
PLOS ONE 12/7 | 2019-07-04 |
2017 |
J. R. Bedarf, F. Hildebrand, L. P. Coelho, S. Sunagawa, M. Bahram, F. Goeser, P. Bork, U. Wüllner Erratum to: Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients published pages: , ISSN: 1756-994X, DOI: 10.1186/s13073-017-0451-z |
Genome Medicine 9/1 | 2019-07-04 |
2016 |
Simone S. Li, Ana Zhu, Vladimir Benes, Paul I. Costea, Rajna Hercog, Falk Hildebrand, Jaime Huerta-Cepas, Max Nieuwdorp, Jarkko Salojärvi, Anita Y. Voigt, Georg Zeller, Shinichi Sunagawa, Willem M. de Vos, Peer Bork Durable coexistence of donor and recipient strains after fecal microbiota transplantation published pages: 586-589, ISSN: 0036-8075, DOI: 10.1126/science.aad8852 |
Science 352/6285 | 2019-05-22 |
2017 |
Daniel R. Mende, Ivica Letunic, Jaime Huerta-Cepas, Simone S. Li, Kristoffer Forslund, Shinichi Sunagawa, Peer Bork proGenomes: a resource for consistent functional and taxonomic annotations of prokaryotic genomes published pages: D529-D534, ISSN: 0305-1048, DOI: 10.1093/nar/gkw989 |
Nucleic Acids Research 45/D1 | 2019-05-22 |
2019 |
Thomas SB Schmidt, Matthew R Hayward, Luis P Coelho, Simone S Li, Paul I Costea, Anita Y Voigt, Jakob Wirbel, Oleksandr M Maistrenko, Renato JC Alves, Emma Bergsten, Carine de Beaufort, Iradj Sobhani, Anna Heintz-Buschart, Shinichi Sunagawa, Georg Zeller, Paul Wilmes, Peer Bork Extensive transmission of microbes along the gastrointestinal tract published pages: , ISSN: 2050-084X, DOI: 10.7554/elife.42693 |
eLife 8 | 2019-04-18 |
2018 |
Thomas S.B. Schmidt, Jeroen Raes, Peer Bork The Human Gut Microbiome: From Association to Modulation published pages: 1198-1215, ISSN: 0092-8674, DOI: 10.1016/j.cell.2018.02.044 |
Cell 172/6 | 2019-04-18 |
2018 |
Katri Korpela, Paul Costea, Luis Pedro Coelho, Stefanie Kandels-Lewis, Gonneke Willemsen, Dorret I. Boomsma, Nicola Segata, Peer Bork Selective maternal seeding and environment shape the human gut microbiome published pages: 561-568, ISSN: 1088-9051, DOI: 10.1101/gr.233940.117 |
Genome Research 28/4 | 2019-04-18 |
2019 |
Falk Hildebrand, Lucas Moitinho-Silva, Sonja Blasche, Martin T Jahn, Toni Ingolf Gossmann, Jaime Huerta-Cepas, Rajna Hercog, Mechthild Luetge, Mohammad Bahram, Anna Pryszlak, Renato J Alves, Sebastian M Waszak, Ana Zhu, Lumeng Ye, Paul Igor Costea, Steven Aalvink, Clara Belzer, Sofia K Forslund, Shinichi Sunagawa, Ute Hentschel, Christoph Merten, Kiran Raosaheb Patil, Vladimir Benes, Peer Bork Antibiotics-induced monodominance of a novel gut bacterial order published pages: gutjnl-2018-3177, ISSN: 0017-5749, DOI: 10.1136/gutjnl-2018-317715 |
Gut | 2019-04-18 |
2017 |
Julia Kleinteich, Falk Hildebrand, Mohammad Bahram, Anita Y. Voigt, Susanna A. Wood, Anne D. Jungblut, Frithjof C. Küpper, Antonio Quesada, Antonio Camacho, David A. Pearce, Peter Convey, Warwick F. Vincent, Christiane Zarfl, Peer Bork, Daniel R. Dietrich Pole-to-Pole Connections: Similarities between Arctic and Antarctic Microbiomes and Their Vulnerability to Environmental Change published pages: 1-11, ISSN: 2296-701X, DOI: 10.3389/fevo.2017.00137 |
Frontiers in Ecology and Evolution 5 | 2019-04-18 |
2018 |
Lisa Maier, Mihaela Pruteanu, Michael Kuhn, Georg Zeller, Anja Telzerow, Exene Erin Anderson, Ana Rita Brochado, Keith Conrad Fernandez, Hitomi Dose, Hirotada Mori, Kiran Raosaheb Patil, Peer Bork, Athanasios Typas Extensive impact of non-antibiotic drugs on human gut bacteria published pages: 623-628, ISSN: 0028-0836, DOI: 10.1038/nature25979 |
Nature 555/7698 | 2019-04-18 |
2018 |
Youssef Darzi, Ivica Letunic, Peer Bork, Takuji Yamada iPath3.0: interactive pathways explorer v3 published pages: W510-W513, ISSN: 0305-1048, DOI: 10.1093/nar/gky299 |
Nucleic Acids Research 46/W1 | 2019-04-18 |
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The information about "MICROBIOS" are provided by the European Opendata Portal: CORDIS opendata.
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