NanoPP
Large Scale Protein Library Screening Biosensor
Total Cost €
0EC-Contrib. €
0Partnership
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0NanoPP project word cloud
Explore the words cloud of the NanoPP project. It provides you a very rough idea of what is the project "NanoPP" about.
Project "NanoPP" data sheet
The following table provides information about the project.
| Coordinator |
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Organization address contact info |
| Coordinator Country | United Kingdom [UK] |
| Total cost | 149˙990 € |
| EC max contribution | 149˙990 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2015-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-01-01 to 2017-06-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE | UK (LONDON) | coordinator | 149˙990.00 |
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Project objective
In this application a platform is proposed that builds on preliminary work from ERC starting grant NanoP in order to develop a technology for high throughput electronic recognition of a large library of proteins using nanometer sized channels. These channel (or nanopore) dimensions are on the same order of magnitude as the proteins that we are using, making a natural confinement mechanism. Importantly, this allows for the efficient detection and screening of individual protein molecules and as will be shown in a high throughput manner. Here we propose to couple protein recognition to an electrical readout via a nanopore, that will result in improved prospects in efficiency, scalability, and sensitivity. Furthermore, this grant will allow for appropriate market research and IP landscaping to be performed in order to ensure the preferred option of setting up a spin-out company will be positioned correctly to ensure success.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2015 |
William H. Pitchford, Hyung-Jun Kim, Aleksandar P. Ivanov, Hyun-Mi Kim, Jae-Seok Yu, Robin J. Leatherbarrow, Tim Albrecht, Ki-Bum Kim, Joshua B. Edel Synchronized Optical and Electronic Detection of Biomolecules Using a Low Noise Nanopore Platform published pages: 1740-1748, ISSN: 1936-0851, DOI: 10.1021/nn506572r |
ACS Nano 9/2 | 2019-07-26 |
| 2015 |
Colin R. Crick, Pablo Albella, Binghao Ng, Aleksandar P. Ivanov, Tyler Roschuk, Michael P. Cecchini, Fernando Bresme, Stefan A. Maier, Joshua B. Edel Precise Attoliter Temperature Control of Nanopore Sensors Using a Nanoplasmonic Bullseye published pages: 553-559, ISSN: 1530-6984, DOI: 10.1021/nl504536j |
Nano Letters 15/1 | 2019-07-26 |
| 2015 |
Aleksandar P. Ivanov, Paolo Actis, Peter Jönsson, David Klenerman, Yuri Korchev, Joshua B. Edel On-Demand Delivery of Single DNA Molecules Using Nanopipets published pages: 3587-3595, ISSN: 1936-0851, DOI: 10.1021/acsnano.5b00911 |
ACS Nano 9/4 | 2019-07-26 |
| 2016 |
Kevin J. Freedman, Colin R. Crick, Pablo Albella, Avijit Barik, Aleksandar P. Ivanov, Stefan A. Maier, Sang-Hyun Oh, Joshua B. Edel On-Demand Surface- and Tip-Enhanced Raman Spectroscopy Using Dielectrophoretic Trapping and Nanopore Sensing published pages: 1036-1044, ISSN: 2330-4022, DOI: 10.1021/acsphotonics.6b00119 |
ACS Photonics 3/6 | 2019-07-26 |
| 2017 |
Ren Ren, Yanjun Zhang, Binoy Paulose Nadappuram, Bernice Akpinar, David Klenerman, Aleksandar P. Ivanov, Joshua B. Edel, Yuri Korchev Nanopore extended field-effect transistor for selective single-molecule biosensing published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-00549-w |
Nature Communications 8/1 | 2019-07-26 |
| 2017 |
Paolo Cadinu, Binoy Paulose Nadappuram, Dominic J. Lee, Jasmine Y. Y. Sze, Giulia Campolo, Yanjun Zhang, Andrew Shevchuk, Sylvain Ladame, Tim Albrecht, Yuri Korchev, Aleksandar P. Ivanov, Joshua B. Edel Single Molecule Trapping and Sensing Using Dual Nanopores Separated by a Zeptoliter Nanobridge published pages: , ISSN: 1530-6984, DOI: 10.1021/acs.nanolett.7b03196 |
Nano Letters | 2019-07-26 |
| 2017 |
Jasmine Y. Y. Sze, Aleksandar P. Ivanov, Anthony E. G. Cass, Joshua B. Edel Single Molecule Multiplexed Nanopore Protein Screening in Human Serum using Aptamer modified DNA Carriers published pages: , ISSN: 2041-1723, DOI: |
Nature Communications | 2019-07-26 |
| 2014 |
Aleksandar P. Ivanov, Kevin J. Freedman, Min Jun Kim, Tim Albrecht, Joshua B. Edel High Precision Fabrication and Positioning of Nanoelectrodes in a Nanopore published pages: 1940-1948, ISSN: 1936-0851, DOI: 10.1021/nn406586m |
ACS Nano 8/2 | 2019-07-26 |
| 2016 |
Kevin J. Freedman, Lauren M. Otto, Aleksandar P. Ivanov, Avijit Barik, Sang-Hyun Oh, Joshua B. Edel Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping published pages: 10217, ISSN: 2041-1723, DOI: 10.1038/ncomms10217 |
Nature Communications 7 | 2019-07-26 |
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