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MOBETA SIGNED

Motor cortical beta bursts for movement planning and evaluation: Mechanisms, functional roles, and development

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MOBETA project word cloud

Explore the words cloud of the MOBETA project. It provides you a very rough idea of what is the project "MOBETA" about.

human    forthcoming    actions    renders    powered    appear    implications    cortical    button    overturn    relate    basis    30hz    examine    power    scissors    performs    lasting    course    monkey    bursts    thinking    theory    behavior    recordings    untenable    aberrant    disorders    sustained    behavioral    functional    occurs    motor    networks    muscle    modeling    longitudinal    13    online    computational    movement    sensory    actually    invasive    provides    evaluation    signaling    interplay    personalized    involve    region    integration    apparent    relatively    signature    unclear    holding    mouse    sheet    paper    relevance    electrophysiological    frequency    thousands    hallmark    substantially    daily    trials    treatments    oscillatory    trial    discrete    transient    each    intricate    slow    multiple    straight    line    averaged    developmental    ongoing    extend    theories    oscillations    pathophysiological    clicking    neuroimaging    infants    healthy    ranging    modal    cut    beta    opportunity    pathological    columns   

Project "MOBETA" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙988˙189 €
 EC max contribution 1˙988˙189 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-COG
 Funding Scheme ERC-COG
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2025-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙988˙189.00

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 Project objective

Each of us performs thousands of actions during the course of daily tasks, ranging from relatively simple (e.g. clicking on a mouse button), to highly complex (e.g. holding a sheet of paper in one hand while using scissors to cut it in a straight line with the other). All of these actions involve an intricate interplay between sensory integration, muscle coordination, and movement evaluation processes. Motor cortical activity in the beta frequency range (13-30Hz) is a hallmark signature of healthy and pathological movement, but its behavioral relevance remains unclear. Recently, it has become apparent that oscillatory beta activity actually occurs in discrete, transient bursts, and that short-lasting, high-powered bursts of activity only appear to be sustained oscillations when averaged over multiple trials. This renders previous theories of beta activity’s functional relevance, which involve slow changes of oscillatory power, untenable. However, this insight provides an exciting opportunity to examine beta activity on a trial-by-trial basis and directly relate it to forthcoming and ongoing motor behavior. Here, I propose a new theory for understanding motor-related beta activity that has the potential to overturn current thinking of the motor role of beta. The proposed project will build upon my recent research and use a multi-modal (electrophysiological recordings, non-invasive neuroimaging, and computational modeling), multi-scale (from cortical columns to multi-region networks), comparative (monkey and human), and developmental (longitudinal measures of human infants) approach to develop and test this theory. Not only will results from this project substantially extend our knowledge on the role of motor-related beta activity, they will have important implications for personalized, online treatments for pathophysiological disorders characterized by aberrant beta signaling.

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The information about "MOBETA" are provided by the European Opendata Portal: CORDIS opendata.

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