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MOBETA SIGNED

Motor cortical beta bursts for movement planning and evaluation: Mechanisms, functional roles, and development

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MOBETA project word cloud

Explore the words cloud of the MOBETA project. It provides you a very rough idea of what is the project "MOBETA" about.

daily    clicking    relevance    holding    course    ongoing    evaluation    muscle    apparent    substantially    developmental    thinking    mouse    performs    involve    healthy    button    lasting    recordings    longitudinal    integration    computational    opportunity    relatively    sustained    forthcoming    overturn    untenable    relate    modal    signaling    personalized    actually    oscillatory    disorders    interplay    aberrant    behavioral    averaged    columns    unclear    online    actions    cut    thousands    electrophysiological    line    signature    trial    beta    discrete    neuroimaging    trials    13    infants    scissors    hallmark    invasive    treatments    intricate    region    extend    oscillations    pathological    networks    occurs    30hz    modeling    behavior    monkey    power    theories    appear    ranging    bursts    multiple    functional    sensory    provides    examine    motor    cortical    movement    pathophysiological    frequency    powered    straight    basis    paper    theory    transient    renders    each    implications    human    slow    sheet   

Project "MOBETA" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙988˙189 €
 EC max contribution 1˙988˙189 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-COG
 Funding Scheme ERC-COG
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2025-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙988˙189.00

Map

 Project objective

Each of us performs thousands of actions during the course of daily tasks, ranging from relatively simple (e.g. clicking on a mouse button), to highly complex (e.g. holding a sheet of paper in one hand while using scissors to cut it in a straight line with the other). All of these actions involve an intricate interplay between sensory integration, muscle coordination, and movement evaluation processes. Motor cortical activity in the beta frequency range (13-30Hz) is a hallmark signature of healthy and pathological movement, but its behavioral relevance remains unclear. Recently, it has become apparent that oscillatory beta activity actually occurs in discrete, transient bursts, and that short-lasting, high-powered bursts of activity only appear to be sustained oscillations when averaged over multiple trials. This renders previous theories of beta activity’s functional relevance, which involve slow changes of oscillatory power, untenable. However, this insight provides an exciting opportunity to examine beta activity on a trial-by-trial basis and directly relate it to forthcoming and ongoing motor behavior. Here, I propose a new theory for understanding motor-related beta activity that has the potential to overturn current thinking of the motor role of beta. The proposed project will build upon my recent research and use a multi-modal (electrophysiological recordings, non-invasive neuroimaging, and computational modeling), multi-scale (from cortical columns to multi-region networks), comparative (monkey and human), and developmental (longitudinal measures of human infants) approach to develop and test this theory. Not only will results from this project substantially extend our knowledge on the role of motor-related beta activity, they will have important implications for personalized, online treatments for pathophysiological disorders characterized by aberrant beta signaling.

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The information about "MOBETA" are provided by the European Opendata Portal: CORDIS opendata.

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