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MOBETA SIGNED

Motor cortical beta bursts for movement planning and evaluation: Mechanisms, functional roles, and development

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MOBETA project word cloud

Explore the words cloud of the MOBETA project. It provides you a very rough idea of what is the project "MOBETA" about.

overturn    electrophysiological    relatively    apparent    motor    ongoing    intricate    region    developmental    computational    opportunity    implications    disorders    infants    relevance    examine    mouse    discrete    bursts    trial    provides    columns    each    recordings    basis    muscle    modal    oscillations    modeling    slow    paper    human    monkey    daily    relate    renders    pathological    pathophysiological    powered    oscillatory    actually    invasive    holding    beta    sensory    personalized    transient    forthcoming    cut    signature    theories    integration    button    thinking    frequency    sustained    appear    functional    behavioral    involve    sheet    treatments    straight    extend    untenable    multiple    performs    unclear    trials    occurs    actions    neuroimaging    theory    13    clicking    ranging    averaged    evaluation    movement    online    behavior    aberrant    line    thousands    lasting    course    substantially    longitudinal    signaling    healthy    cortical    interplay    30hz    scissors    power    networks    hallmark   

Project "MOBETA" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙988˙189 €
 EC max contribution 1˙988˙189 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-COG
 Funding Scheme ERC-COG
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2025-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙988˙189.00

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 Project objective

Each of us performs thousands of actions during the course of daily tasks, ranging from relatively simple (e.g. clicking on a mouse button), to highly complex (e.g. holding a sheet of paper in one hand while using scissors to cut it in a straight line with the other). All of these actions involve an intricate interplay between sensory integration, muscle coordination, and movement evaluation processes. Motor cortical activity in the beta frequency range (13-30Hz) is a hallmark signature of healthy and pathological movement, but its behavioral relevance remains unclear. Recently, it has become apparent that oscillatory beta activity actually occurs in discrete, transient bursts, and that short-lasting, high-powered bursts of activity only appear to be sustained oscillations when averaged over multiple trials. This renders previous theories of beta activity’s functional relevance, which involve slow changes of oscillatory power, untenable. However, this insight provides an exciting opportunity to examine beta activity on a trial-by-trial basis and directly relate it to forthcoming and ongoing motor behavior. Here, I propose a new theory for understanding motor-related beta activity that has the potential to overturn current thinking of the motor role of beta. The proposed project will build upon my recent research and use a multi-modal (electrophysiological recordings, non-invasive neuroimaging, and computational modeling), multi-scale (from cortical columns to multi-region networks), comparative (monkey and human), and developmental (longitudinal measures of human infants) approach to develop and test this theory. Not only will results from this project substantially extend our knowledge on the role of motor-related beta activity, they will have important implications for personalized, online treatments for pathophysiological disorders characterized by aberrant beta signaling.

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The information about "MOBETA" are provided by the European Opendata Portal: CORDIS opendata.

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