Explore the words cloud of the CFQMLD project. It provides you a very rough idea of what is the project "CFQMLD" about.
The following table provides information about the project.
Coordinator |
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Organization address contact info |
Coordinator Country | Germany [DE] |
Project website | https://www.mpipz.mpg.de/tsiantis |
Total cost | 159˙460 € |
EC max contribution | 159˙460 € (100%) |
Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
Code Call | H2020-MSCA-IF-2015 |
Funding Scheme | MSCA-IF-EF-ST |
Starting year | 2017 |
Duration (year-month-day) | from 2017-01-01 to 2018-12-31 |
Take a look of project's partnership.
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1 | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV | DE (MUENCHEN) | coordinator | 159˙460.00 |
Understanding how form emerges in living organisms is a fundamental challenge for biology. Progress, however, has been confounded by the complex chain of interactions underlying the organization of macroscopic forms from molecular processes. Consequently, insights into the manner in which individual genes contribute to the development of form have been elusive; even in well-studied model organisms. In this context, leaves provide a striking example of the self-organization of form – displaying remarkable diversity within and between species. Now, exploiting the close relation between simple leafed A. thaliana and compound leafed C. hirsuta, the Tsiantis lab has identified the key genetic factors underlying their distinct leaf shapes. This opens the door to a detailed understanding of the developmental factors sculpting leaf form.
Due to the complexity of leaf development, however, a mechanistic understanding of these factors requires computational models, informed by detailed quantitative measurements of growth and gene expression. Such models permit the systematic interrogation of the interactions linking genetic regulation, cell division and tissue growth to final form. This action proposes to develop such a computational framework. When combined with experimental efforts, these models promise to help elucidate the regulation of leaf form and provide essential insights into shape regulation in eukaryotic systems. The proposed research is deeply interdisciplinary, working at the interface of computer science and developmental biology. Falling directly at the intersection of the Tsiantis lab's expertise in studying the molecular determinants of leaf form and my expertise in computational modeling of plant development, it fully exploits our relative strengths. Thus providing an ideal vehicle to facilitate essential training while addressing a fundamental research problem.
year | authors and title | journal | last update |
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2018 |
Francesco Vuolo, Daniel Kierzkowski, Adam Runions, Mohsen Hajheidari, Remco A. Mentink, Mainak Das Gupta, Zhongjuan Zhang, Daniela Vlad, Yi Wang, Ales Pecinka, Xiangchao Gan, Angela Hay, Peter Huijser, Miltos Tsiantis LMI1 homeodomain protein regulates organ proportions by spatial modulation of endoreduplication published pages: 1361-1366, ISSN: 0890-9369, DOI: 10.1101/gad.318212.118 |
Genes & Development 32/21-22 | 2019-07-26 |
2019 |
Aleksandra Sapala, Adam Runions, Richard S Smith Mechanics, geometry and genetics of epidermal cell shape regulation: different pieces of the same puzzle published pages: 1-8, ISSN: 1369-5266, DOI: 10.1016/j.pbi.2018.07.017 |
Current Opinion in Plant Biology 47 | 2019-07-26 |
2018 |
Aleksandra Sapala, Adam Runions, Anne-Lise Routier-Kierzkowska, Mainak Das Gupta, Lilan Hong, Hugo Hofhuis, Stéphane Verger, Gabriella Mosca, Chun-Biu Li, Angela Hay, Olivier Hamant, Adrienne HK Roeder, Miltos Tsiantis, Przemyslaw Prusinkiewicz, Richard S Smith Why plants make puzzle cells, and how their shape emerges published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.32794 |
eLife 7 | 2019-07-26 |
2017 |
Adam Runions, Miltos Tsiantis The shape of things to come: From typology to predictive models for leaf diversity published pages: 1437-1441, ISSN: 0002-9122, DOI: 10.3732/ajb.1700251 |
American Journal of Botany 104/10 | 2019-07-26 |
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