Opendata, web and dolomites

SynGenes SIGNED

Defining the genetics of grapheme-colour synaesthesia

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 SynGenes project word cloud

Explore the words cloud of the SynGenes project. It provides you a very rough idea of what is the project "SynGenes" about.

technologies    contribution    suite    platform    public    professional    date    heterogeneous    competitiveness    genes    heritable    underlying    career    researcher    unmask    advancing    community    independent    avenues       1000    individuals    genome    newly    sensory    ascertained    neurogenetics    strategy    wp2    synaesthesia    genetic    grapheme    rare    poorly    prevailing    population    remove    toward    wp3    wp1    neurobiology    diverse    families    letters    plans    perform    hindrance    contributions    informatics    parallel    associate    triggers    variation    landscape    opening    barrier    interrogation    skillset    unrelated    integrative    stakeholders    genetics    utilizing    measured    candidates    outreach    wp4    stimulation    multigenerational    significantly    silico    genotyping    indicates    scientific    add    synaesthetes    training    automatically    complementary    colour    phenomenon    fellowship    familial    discovered    sequencing    quality    supports    deepen    theory    perception    hyperconnectivity    milestones    neurodevelopmental    aetiology    skills    stepping    neural    variants    clustering    sense    reliably    stones   

Project "SynGenes" data sheet

The following table provides information about the project.

Coordinator
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV 

Organization address
address: HOFGARTENSTRASSE 8
city: Munich
postcode: 80539
website: www.mpg.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.mpi.nl/synaesthesia
 Total cost 171˙460 €
 EC max contribution 171˙460 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-06-01   to  2018-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV DE (Munich) coordinator 171˙460.00

Map

 Project objective

Synaesthesia is a common neurodevelopmental phenomenon (2-5% of the population) where stimulation of one sense automatically triggers an experience of another. Familial clustering indicates that synaesthesia is highly heritable. However, this genetic contribution is poorly understood and likely heterogeneous, a major hindrance to our understanding of the neurobiology. My objective is to remove this barrier through the most comprehensive interrogation of synaesthesia genetics to date, utilizing state-of-the-art technologies and integrative approaches. This study will focus on individuals who associate letters and numbers with colour (grapheme-colour synaesthesia), as this type of synaesthesia is common and the most reliably measured. I will apply two complementary approaches in parallel. Whole genome sequencing in two newly ascertained multigenerational synaesthesia families will determine the role of rare genetic variants (Work Package 1, WP1), while genome-wide genotyping of 1000 unrelated synaesthetes will unmask contributions from common variation (WP2). Using existing candidates and novel genes discovered in this work, I will perform multi-level in silico analyses to test if genetic information supports the prevailing theory of neural hyperconnectivity as an underlying aetiology (WP3). WP1-3 will help to define the genetic landscape of synaesthesia, while opening novel research avenues into the neurobiology of sensory perception. This fellowship will provide a diverse set of stepping-stones toward my professional goal of becoming an independent researcher in the rapidly advancing field of neurogenetics. The research and training plans will deepen my current skillset and add a suite of complementary informatics skills that will significantly enhance the quality and competitiveness of my scientific career. The multi-platform dissemination and public outreach strategy involves both the scientific community and main stakeholders at the major milestones (WP4).

 Publications

year authors and title journal last update
List of publications.
2018 Amanda K. Tilot, Katerina S. Kucera, Arianna Vino, Julian E. Asher, Simon Baron-Cohen, Simon E. Fisher
Rare variants in axonogenesis genes connect three families with sound–color synesthesia
published pages: 3168-3173, ISSN: 0027-8424, DOI: 10.1073/pnas.1715492115
Proceedings of the National Academy of Sciences 115/12 2019-06-14

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SYNGENES" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SYNGENES" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

CoCoNat (2019)

Coordination in constrained and natural distributed systems

Read More  

PaSION (2018)

A longitudinal assessment of treatment experience, symptoms and potential associations with biomarkers in cancer patients undergoing immune checkpoint inhibitor therapy

Read More  

GainGrain (2019)

Understanding genetic hubs in rice inflorescence architecture to increase grain yield

Read More