100 Archaic Genomes SIGNED
Genome sequences from extinct hominins
Total Cost €
0EC-Contrib. €
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0100 Archaic Genomes project word cloud
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Project "100 Archaic Genomes" data sheet
The following table provides information about the project.
| Coordinator |
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Project website | https://www.eva.mpg.de/genetics/neandertals-and-more/overview.html |
| Total cost | 2˙350˙000 € |
| EC max contribution | 2˙350˙000 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2015-AdG |
| Funding Scheme | ERC-ADG |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-11-01 to 2021-10-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV | DE (Munich) | coordinator | 2˙350˙000.00 |
Map
Project objective
Neandertals and Denisovans, an Asian group distantly related to Neandertals, are the closest evolutionary relatives of present-day humans. They are thus of direct relevance for understanding the origin of modern humans and how modern humans differ from their closest relatives. We will generate genome-wide data from a large number of Neandertal and Denisovan individuals from across their geographical and temporal range as well as from other extinct hominin groups which we may discover. This will be possible by automating highly sensitive approaches to ancient DNA extraction and DNA libraries construction that we have developed so that they can be applied to many specimens from many sites in order to identify those that contain retrievable DNA. Whenever possible we will sequence whole genomes and in other cases use DNA capture methods to generate high-quality data from representative parts of the genome. This will allow us to study the population history of Neandertals and Denisovans, elucidate how many times and where these extinct hominins contributed genes to present-day people, and the extent to which modern humans and archaic groups contributed genetically to Neandertals and Denisovans. By retrieving DNA from specimens that go back to the Middle Pleistocene we will furthermore shed light on the early history and origins of Neandertals and Denisovans.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2017 |
Gokhman, D.; Agranat-Tamir, L.; Housman, G.; Nissim-Rafinia, M.; Nieves-Colón, M.; Gu, H.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Quillen, E.; Meissner, A.; Stone, A.; Pusey, A.; Mjungu, D.; Kandel, L.; Liebergall, M.; Prada, M.; Vidal, J.; Krause, J.; Yakir, B.; Pääbo, S.; Reich, D.; Lalueza-Fox, C.; Marques-Bonet, T.; Meshorer, E.; Carmel, L. Recent regulatory changes shaped human facial and vocal anatomy published pages: , ISSN: , DOI: 10.1101/106955 |
1 | 2019-09-04 |
| 2018 |
Petra Korlević, Sahra Talamo, Matthias Meyer A combined method for DNA analysis and radiocarbon dating from a single sample published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-22472-w |
Scientific Reports 8/1 | 2019-09-04 |
| 2019 |
Martin Petr, Svante Pääbo, Janet Kelso, Benjamin Vernot Limits of long-term selection against Neandertal introgression published pages: 1639-1644, ISSN: 0027-8424, DOI: 10.1073/pnas.1814338116 |
Proceedings of the National Academy of Sciences 116/5 | 2019-09-04 |
| 2018 |
Viviane Slon, Fabrizio Mafessoni, Benjamin Vernot, Cesare de Filippo, Steffi Grote, Bence Viola, Mateja Hajdinjak, Stéphane Peyrégne, Sarah Nagel, Samantha Brown, Katerina Douka, Tom Higham, Maxim B. Kozlikin, Michael V. Shunkov, Anatoly P. Derevianko, Janet Kelso, Matthias Meyer, Kay Prüfer, Svante Pääbo The genome of the offspring of a Neanderthal mother and a Denisovan father published pages: 113-116, ISSN: 0028-0836, DOI: 10.1038/s41586-018-0455-x |
Nature 561/7721 | 2019-09-04 |
| 2019 |
Thibaut Devièse, Diyendo Massilani, Seonbok Yi, Daniel Comeskey, Sarah Nagel, Birgit Nickel, Erika Ribechini, Jungeun Lee, Damdinsuren Tseveendorj, Byambaa Gunchinsuren, Matthias Meyer, Svante Pääbo, Tom Higham Compound-specific radiocarbon dating and mitochondrial DNA analysis of the Pleistocene hominin from Salkhit Mongolia published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-08018-8 |
Nature Communications 10/1 | 2019-09-04 |
| 2017 |
Thibaut Devièse, Ivor Karavanić, Daniel Comeskey, Cara Kubiak, Petra Korlević, Mateja Hajdinjak, Siniša Radović, Noemi Procopio, Michael Buckley, Svante Pääbo, Tom Higham Direct dating of Neanderthal remains from the site of Vindija Cave and implications for the Middle to Upper Paleolithic transition published pages: 10606-10611, ISSN: 0027-8424, DOI: 10.1073/pnas.1709235114 |
Proceedings of the National Academy of Sciences 114/40 | 2019-06-13 |
| 2017 |
Viviane Slon, Charlotte Hopfe, Clemens L. Weiß, Fabrizio Mafessoni, Marco de la Rasilla, Carles Lalueza-Fox, Antonio Rosas, Marie Soressi, Monika V. Knul, Rebecca Miller, John R. Stewart, Anatoly P. Derevianko, Zenobia Jacobs, Bo Li, Richard G. Roberts, Michael V. Shunkov, Henry de Lumley, Christian Perrenoud, Ivan Gušić, Željko Kućan, Pavao Rudan, Ayinuer Aximu-Petri, Elena Essel, Sarah Nagel, Birgit Nickel, Anna Schmidt, Kay Prüfer, Janet Kelso, Hernán A. Burbano, Svante Pääbo, Matthias Meyer Neandertal and Denisovan DNA from Pleistocene sediments published pages: 605-608, ISSN: 0036-8075, DOI: 10.1126/science.aam9695 |
Science 356/6338 | 2019-06-13 |
| 2017 |
Melinda A. Yang, Xing Gao, Christoph Theunert, Haowen Tong, Ayinuer Aximu-Petri, Birgit Nickel, Montgomery Slatkin, Matthias Meyer, Svante Pääbo, Janet Kelso, Qiaomei Fu 40,000-Year-Old Individual from Asia Provides Insight into Early Population Structure in Eurasia published pages: 3202-3208.e9, ISSN: 0960-9822, DOI: 10.1016/j.cub.2017.09.030 |
Current Biology 27/20 | 2019-06-13 |
| 2018 |
Mateja Hajdinjak, Qiaomei Fu, Alexander Hübner, Martin Petr, Fabrizio Mafessoni, Steffi Grote, Pontus Skoglund, Vagheesh Narasimham, Hélène Rougier, Isabelle Crevecoeur, Patrick Semal, Marie Soressi, Sahra Talamo, Jean-Jacques Hublin, Ivan Gušić, Željko Kućan, Pavao Rudan, Liubov V. Golovanova, Vladimir B. Doronichev, Cosimo Posth, Johannes Krause, Petra Korlević, Sarah Nagel, Birgit Nickel, Montgomery Slatkin, Nick Patterson, David Reich, Kay Prüfer, Matthias Meyer, Svante Pääbo, Janet Kelso Reconstructing the genetic history of late Neanderthals published pages: 652-656, ISSN: 0028-0836, DOI: 10.1038/nature26151 |
Nature 555/7698 | 2019-06-13 |
| 2017 |
Kay Prüfer, Cesare de Filippo, Steffi Grote, Fabrizio Mafessoni, Petra Korlević, Mateja Hajdinjak, Benjamin Vernot, Laurits Skov, Pinghsun Hsieh, Stéphane Peyrégne, David Reher, Charlotte Hopfe, Sarah Nagel, Tomislav Maricic, Qiaomei Fu, Christoph Theunert, Rebekah Rogers, Pontus Skoglund, Manjusha Chintalapati, Michael Dannemann, Bradley J. Nelson, Felix M. Key, Pavao Rudan, Željko Kućan, Ivan Gušić, Liubov V. Golovanova, Vladimir B. Doronichev, Nick Patterson, David Reich, Evan E. Eichler, Montgomery Slatkin, Mikkel H. Schierup, Aida M. Andrés, Janet Kelso, Matthias Meyer, Svante Pääbo A high-coverage Neandertal genome from Vindija Cave in Croatia published pages: 655-658, ISSN: 0036-8075, DOI: 10.1126/science.aao1887 |
Science 358/6363 | 2019-06-13 |
| 2017 |
Viviane Slon, Bence Viola, Gabriel Renaud, Marie-Theres Gansauge, Stefano Benazzi, Susanna Sawyer, Jean-Jacques Hublin, Michael V. Shunkov, Anatoly P. Derevianko, Janet Kelso, Kay Prüfer, Matthias Meyer, Svante Pääbo A fourth Denisovan individual published pages: e1700186, ISSN: 2375-2548, DOI: 10.1126/sciadv.1700186 |
Science Advances 3/7 | 2019-06-13 |
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