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NanoSil4Cancer

Smart Multifunctional silica-based Nanoparticles for Targeted Therapy

Total Cost €

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EC-Contrib. €

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Partnership

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 NanoSil4Cancer project word cloud

Explore the words cloud of the NanoSil4Cancer project. It provides you a very rough idea of what is the project "NanoSil4Cancer" about.

environmental    vehicles    accelerate    nano    innovative    chemotherapy    feasibility    sensitive    internalized    pro    toxicity    pct    prototypes    customers    released    dosage    adherence    marketing    saving    bortezomib    active    cells    antitumor    commercial    nanoparticles    proprietary    cancer    folic    silica    trend    customer    minimizing    smart    search    sparing    nevertheless    lowering    sectorial    ep06745236    stakeholder    strategical    acid    individuate    fr    missing    therapeutic    drugs    optimized    agents    dramatically    ph    receptor    final    sme    limited    big    normal    patent    report    mesoporous    13511    acquire    depends    release    thomson    therapy    overexpressing    nanosil4cancer    compartments    efficacy    drug    patients    interests    market    90    medical    molecules    buy    communication    formulated    prototype    device    platform    technologies    epo    nanotechnologies    intracellular    attractiveness    business    minimize    290b    folate    healthcare    competence    pharma   

Project "NanoSil4Cancer" data sheet

The following table provides information about the project.

Coordinator
NANOSILICAL DEVICES SRL 

Organization address
address: VIA PIETRO BUCCI CUBO 44A
city: RENDE
postcode: 87036
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.nanosilicaldevices.com/it/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2017-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NANOSILICAL DEVICES SRL IT (RENDE) coordinator 50˙000.00

Map

 Project objective

NanoSil4Cancer project will be able to accelerate the uptake of nanotechnologies, by developing, mesoporous silica-based prototypes of nano-vehicles, according to an innovative and proprietary approach (EP06745236), active in smart chemotherapy. This is aimed to minimize toxicity and the side effects of the traditional antitumor agents and to increase their therapeutic potential. This technology platform enables customers’ molecules to be formulated as pH–sensitive pro-drugs and introduced in smart nanoparticles able to reach the intracellular compartments of cancer cells where the drug is released. Development of new prototypes will lead to new patent applications. Recently we have developed and optimized a device, provided with folic acid, able to manage bortezomib release in cancer cells overexpressing folate receptor, FR (PCT-13511). The nanoparticles are only recognized and internalized by FR overexpressing cancer cells, where they release the drug, sparing normal cells. Nevertheless, our technology is general, not limited to a specific prototype, but depends on customer's needs, market and final users' needs. The feasibility study will individuate strategical market interests to address the prototypes production as business opportunities for our SME. Market trend and the role of Big Pharma will be defined to identify commercial partners and stakeholder to be involved in the project. We will buy sectorial report, we will use patent search such as EPO and Thomson, we will acquire missing competence in marketing and communication. The approach will represent a strong step forward in chemotherapy, improving the efficacy, lowering drug dosage (thus minimizing side effects for cancer patients and environmental impact), other than dramatically lowering EU Healthcare costs (up to 80-90% saving on non-adherence to the therapy costs, estimated in $290B/year), allowing Europe to increase its attractiveness in the field of innovative medical technologies.

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The information about "NANOSIL4CANCER" are provided by the European Opendata Portal: CORDIS opendata.

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