The page lists 326 projects related to the topic "receptor".
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1 | APERIM | APERIM: Advanced bioinformatics platform for PERsonalised cancer IMmunotherapy | 2015 |
2 | BETA3_LVH | A multi-center randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease | 2015 |
3 | PentaBrain | Structural studies of mammalian Cys-loop receptors | 2015 |
4 | SILENCE | Mechanisms of Gene Silencing by the Glucocorticoid Receptor | 2015 |
5 | DNAendProtection | DNA end protection in Immunity and Cancer | 2015 |
6 | Crosstag | Unravelling cross-presentation pathways using a chemical biology approach | 2015 |
7 | DE-ORPHAN | DEtermination of Orphan Receptor PHysiological Agonists and sigNals | 2015 |
8 | CannaPreg | Development of pregnenolone derivatives as allosteric inhibitors of CB1 cannabinoid receptors for the treatment of schizophrenia and psychotic syndromes | 2015 |
9 | ONCORNET | ONCOgenic Receptor Network of Excellence and Training | 2015 |
10 | BIOGEL | Engineering responsive and biomimetic hydrogels for biomedical therapeutic and diagnostic applications | 2015 |
11 | EpiPredict | Epigenetic regulation of endocrine therapy resistance in breast cancer: A systems medicine approach to predict treatment outcome | 2015 |
12 | BonePain | European Training Network on Bone Pain | 2015 |
13 | TREGeneration | Repair of tissue and organ damage in refractory chronic graft versus host disease after hematopoietic stem cell transplantation by the infusion of purified allogeneic donor regulatory T lymphocytes | 2015 |
14 | OCN4OS | Organo-Catalytic Nanoparticles for Organic Synthesis | 2015 |
15 | gluactive | Activation Mechanism of a Glutamate Receptor | 2015 |
16 | GLYCO-TOOLS | Bio-Inspired Tools for Glycoscience | 2015 |
17 | BIZEB | Bio-Imaging of Zoonotic and Emerging Bunyaviruses | 2015 |
18 | CircaDopamine | The Role of Dopamine in the Regulation of Sleep and Circadian Rhythms | 2015 |
19 | EMCOP9CRL | Structural basis of Cullin-RING ligase regulation by the COP9 signalosome | 2015 |
20 | PERFECTION | Probing mechanisms of pathogen effector recognition by plant Resistance proteins to elevate defence gene activation | 2016 |
21 | DDRR | Dissecting dsRNA uptake in RNAi-based antiviral immunity | 2015 |
22 | BATTLE | The molecular basis of NleB-mediated bacterial virulence | 2016 |
23 | NIMBLIS | Laser Induced Synthesis of Biocompatible Multifunctional Inorganic Nanoparticles: A Novel Route to Produce Multifunctional Contrast Agents for Early Diagnosis of Breast Cancer | 2016 |
24 | NANOCARB | Self-selection of a multivalent nanosystem for carbohydrate recognition | 2015 |
25 | DecipherBILU | Understanding functional mechanisms leading to the BILU syndrome | 2015 |
26 | CoordinGrowthDev | Characterization of the mechanism of inter-organ communication coordinating tissue growth and developmental timing | 2016 |
27 | SCARtool | Scattered radiation reduction tool to improve computer-aided diagnosis performance in digital breast tomosynthesis | 2015 |
28 | breast cancer dormancy | Molecular characterisation of a clinical model of estrogen receptor-positive breast cancer dormancy | 2015 |
29 | ARENAVIRUS | Molecular mechanisms of arenavirus cell entry and antibody-mediated neutralization | 2015 |
30 | CARiPSCTcells | Generation of safe and efficient, off-the-shelf, chimeric antigen receptor (CAR)-engineered T cells for broad application | 2015 |
31 | ROR2BONE | Investigating Ror2-dependent non-canonical Wnt signaling in bone remodeling | 2015 |
32 | MACROIMAGING | Specific Fluorogenic Peptides for Imaging Metastasis-associated Macrophages | 2015 |
33 | SSPinROOTS | Small Signalling Peptides for Stimulating Root Growth - a Novel Approach to Improve Nutrient Use Efficiency | 2015 |
34 | Glial-Puberty | The role of Glial cells in the control of puberty | 2016 |
35 | CR-PHAGOCYTOSIS | Complement-mediated phagocytosis in neutrophils | 2015 |
36 | CICCI | Characterization of Intestinal Cancer Cell Invasion | 2015 |
37 | EVOLPREG | Origination of novel gene regulatory networks in the evolution of mammalian pregnancy | 2016 |
38 | MEMBRANEPROT | Membrane proteins – development of new computational approaches and its application to G-Protein Coupled Receptors | 2016 |
39 | SorCSbalance | Role of the sorting receptor SorCS1 in controlling excitation/inhibition balance in neural circuits. | 2015 |
40 | EGFR-Activ | Epidermal growth factor receptor (EGFR) activation by cytohesins - Structural Insights | 2015 |
41 | BRACE | Breaking down arenavirus cell entry | 2015 |
42 | SORT1LIG | Identification and characterization of new cytosolic ligands of Sortilin | 2016 |
43 | WntTraffic | Characterising the spatial organisation and regulation of the Wnt receptor complex in stem cells and cancer | 2016 |
44 | LYMPHOSIGN | Integrated study of the role of B-cell receptor signaling in the development of Follicular Lymphoma | 2015 |
45 | TITLY | Inhibition of the T-cell receptor signalling pathway for treatment of T-cell lymphoma | 2015 |
46 | UbiGABA | The role of ubiquitination in stability and plasticity of the GABAergic synapse | 2015 |
47 | BI-MARK | Clinical validation of the CD32b biomarker on the European market | 2015 |
48 | NEWCARBOVAX | New generation of carbohydrate-based vaccines via rational understanding of their immunological mechanism | 2017 |
49 | NanoSmell | NanoSmells: Artificial remote-controlled odorants | 2015 |
50 | VERTICAL CITY | Versatility of scaffold complexes in vivo to control synaptic plasticity | 2015 |
51 | ER_disease | Defining hormonal cross-talk and the role of mutations in estrogen receptor positive breast cancer | 2015 |
52 | CONCERT | Description of information transfer across macromolecules by concerted conformational changes | 2015 |
53 | CARDYADS | Controlling Cardiomyocyte Dyadic Structure | 2015 |
54 | FLYghtCaRe | Ca2+ feedback control of TRP/TRPL channels in Drosophila photoreceptors | 2015 |
55 | MucoVac | Unravelling the mode of action of mucosal adjuvants | 2016 |
56 | HOARDEVOL | The evolution of food hoarding: from environmental pressures to brain mechanisms | 2016 |
57 | CilDyn | Molecular analysis of the Hedgehog signal transduction complex in the primary cilium | 2015 |
58 | PROGSY | Prosaposin and GPR37 in synucleinopathies | 2015 |
59 | CaSR Biomedicine | Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases | 2016 |
60 | MeLiLoN | Metabolic Networks that Link Longevity to Reproduction in Response to Nutrition | 2015 |
61 | p38Cure | New breast cancer therapies based on available p38 MAPK inhibitors | 2015 |
62 | SurfaceInhibition | The role of 5HT3a inhibitory interneurons in sensory processing | 2015 |
63 | IL7sigNETure | IL-7/IL-7R signaling networks in health and malignancy | 2015 |
64 | ISOTOPICS | ISOTOPIC LABELING FOR DRUG INNOVATION | 2016 |
65 | GENESIS | GENEtic DiSsection of Innate Immune Sensing and Signalling | 2015 |
66 | CsnCRL | The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome | 2016 |
67 | ImmunityByPairDesign | Design and redesign of a plant immune receptor complex | 2015 |
68 | SYNECT | Immunological synapse derived ectosomes in T cell effector function | 2015 |
69 | PRION2020 | Function and malfunction of the prion protein | 2015 |
70 | AcTafactors | AcTafactors: Tumor Necrosis Factor-based immuno-cytokines with superior therapeutic indexes | 2015 |
71 | PolyDrug Discovery | Discovery of anticancer polymeric drugs that mimic the action of TRAIL | 2016 |
72 | channelopathies | Type 1 reyanodine receptor Structure and regulation by post-translational modifications and small molecules. | 2016 |
73 | ThruBlood | Clinical validation of Trop-2 as a serum biomarker for monitoring of disease-course in patients affected by breast and colon cancer | 2016 |
74 | CaNANObinoids | From Peripheralized to Cell- and Organelle-Targeted Medicine: The 3rd Generation of Cannabinoid-1 Receptor Antagonists for the Treatment of Chronic Kidney Disease | 2016 |
75 | NEUTRO-LILR | Leukocyte immunoglobulin-like receptors (LILRs) on neutrophils | 2016 |
76 | OPRAS | Olfactory processing of repellent and attractive stimuli in the brain of Drosophila | 2017 |
77 | OptoNMDA | Optical strategies to investigate NMDA receptor functional diversity and its therapeutic potential | 2016 |
78 | IFNBetaMito | Role of IFN-β in mitochondrial homeostasis and impact on Parkinson Disease | 2016 |
79 | LIPID IMMUNITY | Regulation of lipid-mediated immunity in the intestine | 2016 |
80 | MCANALSMSCA2015 | Receptor signalling in space and time - Gaining high-resolution information of the temporal and spatial control of G protein-coupled receptor signalling. | 2018 |
81 | CorCir | Cortical circuit assembly in the developing mouse neocortex | 2017 |
82 | CHERI | Chromatin targeting and remodelling by bacterial effectors in plant immunity | 2016 |
83 | PYANO | Retargeted Pyocins: A novel tool for combating major food borne pathogens and exploitingphage-host interactions | 2016 |
84 | RAMSES | Aryl amide metallofoldamersas selective saccharide sensors | 2016 |
85 | DynaSpaCER | Molecular Mechanisms of Dynamic and Spatial Control of Eph Receptors clustering | 2016 |
86 | ADHERE | Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy | 2016 |
87 | DrugCrops | Drought discovery to improve drought tolerance in crops | 2017 |
88 | GENDER-CF | Gender-related differences in expression of microRNAs in cystic fibrosis | 2017 |
89 | ZF-ILC | Characterization of zebrafish innate lymphoid cells and IL-22 | 2017 |
90 | JHSIGNAL | Modulation of juvenile hormone signaling by receptor phosphorylation | 2017 |
91 | STrkB | The structural biology of TrkB-BDNF signalling | 2017 |
92 | REFOLDAMER | Communication through Polarity-Switchable Foldamers | 2016 |
93 | NANOZ-ONIC | Bio-inspired electrONIC NOSE interfacing olfactory electrical biosensors and carbon NANOtubes | 2016 |
94 | NMDARETT | Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits | 2016 |
95 | GUIDESIGINT | Competitive assembly dynamics of the DCC receptor with its guidance cues integrates signals for cellular steering | 2017 |
96 | CD4DNASP | Cell intrinsic control of CD4 T cell differentiation by cytosolic DNA sensing pathways | 2016 |
97 | nextDART | Next-generation Detection of Antigen Responsive T-cells | 2016 |
98 | VIREX | Mumps VIRus EXploitation of the human adhesion receptor GPR125 | 2016 |
99 | ImmunoBile | Bile acid, immune-metabolism, lipid and glucose homeostasis | 2016 |
100 | TagIt | A Minimal-Tag Bioorthogonal Labelling Approach to Protein Uptake, Traffic and Delivery | 2016 |
101 | PLEIO-RANK | Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity | 2016 |
102 | PROVASC | Cell-specific vascular protection by CXCL12/CXCR4 | 2016 |
103 | NMDADYN | NMDA receptor diversity: from molecular dynamics to synaptic physiopathology | 2016 |
104 | Autonomous CLL-BCRs | Role of autonomous B cell receptor signalling and external antigen in the pathogenesis of chronic lymphocytic leukaemia (CLL) | 2016 |
105 | NanoSil4Cancer | Smart Multifunctional silica-based Nanoparticles for Targeted Therapy | 2016 |
106 | ONOFF | Perception of voices that do not exist: Tracking the temporal signatures of auditory hallucinations | 2016 |
107 | GRO-BAT | Growth hormone: an endocrine factor that integrates thermogenic and circadian signals to regulate brown adipose tissue activity. | 2016 |
108 | TaGFrag | Stabilising Protein-Protein Interactions: A Target-Guided Fragment-Based Approach | 2016 |
109 | SPLICECODE | Alternative Splicing Codes for Synaptic Specificity | 2016 |
110 | BITCAT | Blocking Inhibition of T-cell Co-stimulation for Anti-tumour Therapy | 2017 |
111 | SEMA3C | Genetic dissection of the SEMA3C/Neuropilin 1 signalling pathway in Chronic Kidney Disease progression | 2016 |
112 | PAPA | Pathophysiology of Primary Aldosteronism | 2017 |
113 | MULTIFUNSOME | Anti-EGFR Monoclonal Antibody Conjugated Thermoresponsive Liposome for Triple Negative Breast Cancer Thermo-Chemotherapy | 2017 |
114 | NanoCellActivity | Nanoscale live-cell activity sensing using smart probes and imaging | 2017 |
115 | MMA | Molecular Mechanical Adhesives | 2017 |
116 | INHIBITHUMAN | Dis-inhibitory circuits in the human cerebral cortex | 2016 |
117 | Neuroheart | Cardiovascular Molecular Imaging for Personalized Tailored Treatment | 2017 |
118 | GUTPEPTIDES | Novel therapeutic approaches to improve gastrointestinal wound healing | 2017 |
119 | NANOGLU | Enlightening synaptic architecture: nanoscale segregation of glutamate receptor subtypes | 2017 |
120 | EURE-CART | EURopean Endeavour for Chimeric Antigen Receptor Therapies | 2017 |
121 | MODulATE | Gut microbiota-dependent tryptophan metabolism: role in disease pathogenesis and therapeutic target | 2017 |
122 | VAHVISTUS | Integrative development of smart drug-vector nanostructures for adaptive delivery to target cells | 2017 |
123 | iNAPS | Illuminating Neuronal-Astrocytic Pathways for Sleep homeostasis | 2017 |
124 | STRUGGLE | Statistical physics of immune-viral co-evolution | 2017 |
125 | CARBOFLU | Chemoenzymatic synthesis of complex glycans to decipher the interactions between them and Influenza A virus | 2017 |
126 | BRECASTEM | Functional and Molecular Characterisation of Breast Cancer Stem Cells | 2017 |
127 | INVESTIGERFE | Investigating the regulation of iron homeostasis by erythroferrone and therapeutic applications | 2017 |
128 | TRPLigDrugConj | TRPV1-targeted ligand-drug conjugates to treat prostate cancer | 2017 |
129 | GlycoModels | 3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management | 2017 |
130 | GLYCONHC | Exploiting carbohydrate/N-heterocyclic carbene hybrid complexes as innovative multifunctional oxidation catalysts with tailoring of weak interactions allowing for development of enzyme mimics | 2017 |
131 | NeuroModSense | Peptidergic Neuromodulation of Sensory Representation in the Brain | 2017 |
132 | GD TCR LIGAND | Identification of the ligand of a human public anti-HCMV/cancer γδ T cell receptor | 2017 |
133 | C18Signaling | Regulation of Cellular Growth and Metabolism by C18:0 | 2017 |
134 | MultiLevelLandscape | Multilevel Selection for Specificity and Divergence in Bacteria | 2017 |
135 | MAREXT | Macrocyclic receptors for selective anion extraction | 2018 |
136 | Cytokine Signalosome | Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands | 2017 |
137 | MIREDI | Mechanisms of Immune Receptor Diversification in Cereals | 2017 |
138 | TOPPER | Targeting of host proteins by unrelated pathogen effectors and their surveillance by allelic immune receptors | 2018 |
139 | ThromboForce | Platelet tractions through the Glycoprotein (GP) GPIb receptor as a potential marker for platelet reactivity | 2017 |
140 | MitoDyaD | The role of the glucocorticoid receptor in dopaminoceptive neurons in mitochondrial dysfunction and vulnerability to depression | 2017 |
141 | DevoSignGammaDelta | Tracking γδ T cell development and TCRγδ proximal signalling | 2018 |
142 | WallWatchers | Plant cell wall communication and remodelling: the wall watchers. | 2017 |
143 | MArylAND | At the host-bacteria interface: Modulation of the intestinal microbiota and its metabolic activity by Card9 signalling in health and Inflammatory Bowel Diseases | 2017 |
144 | FISHODOR | Integrating conspecific odors into tilapia reproductive behaviour | 2017 |
145 | RTKPalm | Modulating and Profiling Receptor Tyrosine Kinase S-palmitoylation in Breast Cancer | 2017 |
146 | ARC-NeuroHet | Unravelling neuronal heterogeneity in energy homeostasis regulation | 2017 |
147 | AcTaferon | Revitalizing the clinical potential of type I IFNs in fighting influenza A virus infections with AcTaferon. | 2017 |
148 | PHAGO | Inflammation and AD: modulating microglia function focussing on TREM2 and CD33 - Sofia ref.: 115976 | 2016 |
149 | CHI-ZEF | Cdon-Hh Interaction: functional in vivo analysis in zebrafish | 2017 |
150 | CD4CRISPR | A quorum sensing mechanism regulating CD4 T cell proliferation | 2017 |
151 | CRYO-EM TRPV5 | Structure-function analysis of the calcium channel TRPV5 | 2017 |
152 | RoNDBioCan | NLRP3 in cancer: Deciphering the role of NLRP3 in the DNA Damage response pathway | 2018 |
153 | THAT IS HUNT | Triggering Haematological Adoptive T-cell Immunotherapy Strategies by HUnting Novel T-cellreceptors | 2018 |
154 | CAR ART | Chimeric Antigen Receptor to generate Alloantigen-specific Regulatory T cells and promote allograft tolerance | 2017 |
155 | DYNAMO | Structural Dynamics of Membrane Receptors at native-like conditions | 2018 |
156 | EpiPur | The ATP-P2X7R axis: a target for drug-refractory epilepsy | 2018 |
157 | INIMUD | Impact of Neuromedin U in type 2 immunity and mucosal defence | 2017 |
158 | ONCOSYSTEMS | Phenotypic characterization of Liver-derived exosomes populations associated with liver metastasis in pancreatic cancers | 2017 |
159 | Signalling-in-NODs | Investigation of the role and mechanism of action of NOD2-mediated isoform selective PI3K signalling in gut immunity and inflammation | 2017 |
160 | BEAT | The functional interaction of EGFR and beta-catenin signalling in colorectal cancer: Genetics, mechanisms, and therapeutic potential. | 2017 |
161 | GLUCOTANYCYTES | Glucotanycytes: a role for hypothalamic barriers in the control of metabolism by peripheral glucose | 2017 |
162 | MagneticMoth | Hunting for the elusive “sixth” sense: navigation and magnetic sensation in a nocturnal migratory moth | 2017 |
163 | StressPFCog | Mechanisms of stress-induced cognitive deficits : Role of the glucocorticoid receptor and its partners in the regulation of PFC function. | 2018 |
164 | FRAGMENT2DRUG | Jigsaw puzzles at atomic resolution: Computational design of GPCR drugs from fragments | 2017 |
165 | TIGITtherapy | TIGIT therapy for cancer treatment | 2017 |
166 | BLASTOFF | Retooling plant immunity for resistance to blast fungi | 2017 |
167 | gdTCR-Ligand | Investigating the recognition of a novel ligand by gamma-delta T cells and the translation of this interaction into molecules for future cancer immunotherapy | 2017 |
168 | ALLERGUT | Mucosal Tolerance and Allergic Predisposition: Does it all start in the gut? | 2017 |
169 | NEMESIS | Neuron/mast cell interactions in skin diseases | 2017 |
170 | PurinesDX | Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases. | 2017 |
171 | SAFER | Selective Agonists For Serotonin Receptors | 2017 |
172 | SELFOR | How our adaptive immune system separates “self” from “foreign” – a physicochemical study of binding in cell contacts | 2018 |
173 | VDJtargeting | Engineering T cells and B cells for Immunotherapy using V(D)J recombination | 2017 |
174 | onCOMBINE | Towards evidence-based combinations of approved and novel cancer drugs | 2017 |
175 | TRIPLECON | Triple negative breast cancer control through synergistic inhibition of EGFR and CDK9 signaling | 2017 |
176 | FAITh | Fighting Anxiety with Importin-based Therapeutics | 2017 |
177 | GlypStx | Glycoprotein-based inhibitors of shiga-like toxin | 2018 |
178 | BILITOLERANCE | Control of disease tolerance to infection by Biliverdin Reductase A | 2018 |
179 | MESI-STRAT | Systems Medicine of Metabolic-Signaling Networks: A New Concept for Breast Cancer Patient Stratification | 2018 |
180 | Brain2Bee | How dopamine affects social and motor ability - from the human brain to the honey bee | 2018 |
181 | CLLCLONE | Harnessing clonal evolution in chronic lymphocytic leukemia | 2018 |
182 | DiSect | The Tumour Stroma as a Driver of Clonal Selection | 2018 |
183 | SI | Structural and functional characterization of the ICOS/ICOSL immune complex | 2018 |
184 | UTERUS | Unravelling gamma delta T cell emergence and responses in the uterus | 2018 |
185 | HIV B Cell Function | Understanding HIV-specific B cell function and viral immunogenicity | 2018 |
186 | Acclimatize | Hypothalamic mechanisms of thermal homeostasis and adaptation | 2018 |
187 | KARhet | Molecular architecture of heteromeric kainate receptor complexes | 2018 |
188 | SPLINTER | Signaling of plant intracellular immune receptors | 2018 |
189 | EFHHBBBMS | Endothelial Hedgehog autocrine signaling at the Blood Brain Barrier controls inflammatory CentralNervous System lesion size and severity through Gas1 co-receptor modulation. | 2019 |
190 | INTERGLU | Dissecting mGlu5 receptor internalization pathways using genetic and pharmacological tools | 2018 |
191 | CXCR4THERAPY | IMPROVING HEMATOPOIETIC STEM CELL- BASED GENE THERAPY OUTCOME BY MODULATING CXCR4 EXPRESSION | 2018 |
192 | DC-SIGN-MFN | Dissecting Multivalent Viral Receptor-carbohydrate Interactions Using Polyvalent Multifunctional Glycan-Quantum Dot | 2018 |
193 | EDIOS | Evolutionary development of the insect olfactory system | 2018 |
194 | TRECEPTORS | Transport and Receptor Mechanisms of Human Solute Carriers | 2018 |
195 | IMMUNO-PEPTALK | Regulation of plant receptor kinase-mediated immunity by endogenous peptides and their receptors | 2018 |
196 | RECGLYCANMR | Breaking the limits in glycan recognition by NMR | 2018 |
197 | HGB-StIC | Human Genetic Basis of Severe Staphylococcal Infections in Childhood | 2019 |
198 | SPeNTa-Brain | Synthetic Peptidic Nanovesicles for Targeting Paediatric Brain tumours | 2019 |
199 | MTBHLAE | Investigation of a novel immune cell type in Tuberculosis: characterization of the specificity, function and pathogen killing ability of T cells restricted by non-classical HLA-E molecules | 2018 |
200 | ASTRO_ECM | Deciphering the role of astrocytes in chronic depression. | 2018 |
201 | FA x Force | Reconstitution and Structural Analysis of a Minimal Mechanosensitive Focal Adhesion Complex | 2019 |
202 | LEVADAPT | Identification of new regulators of Acetylcholine receptor using the nematode Caenorhabditis elegans | 2018 |
203 | NLR_NLR-ID power | NLR-ID diversity, mechanism and functionality upon transfer between species | 2018 |
204 | rSAMs-NANO | Nanoparticles with switchable shells for virus sensing and inhibition | 2018 |
205 | NMRSIGN | NMR insights on the soluble Guanylyl Cyclase conformational dynamics to illuminate the SIGNaling pathway | 2018 |
206 | NACHO | Nicotine actions on beta cell function in health and disease | 2018 |
207 | Flat_Leaf | How to grow a flat leaf? | 2019 |
208 | IGpath | Dissecting the functional pathways of B cell receptor immunoglobulin in antigen driven mature B cell lymphomas | 2018 |
209 | EpiBarrier | Control of the blood-brain barrier integrity during seizures via the ATP-gated P2X7 receptor | 2018 |
210 | simpetmr | Development of quantification procedures for simultaneous PET-MR data for human brain imaging | 2018 |
211 | UNNAMEd-2 | Unraveling the conceptional novel ADAM17 regulation by PP2A in metastasis formation. | 2019 |
212 | FUCTURE | Fucosylated Clusterin: a novel mechanism of tumor escape from immune response | 2018 |
213 | ML Potentials | Constructing Intermolecular Potentials by Combining Physics and Machine Learning | 2018 |
214 | TAMYOCAL | Tamoxifen mediated protection on X-linked centronuclear myopathy: a mechanistic and pre-clinical study | 2018 |
215 | ProMeta | Non-histone protein acetylation targets of KAT2A in AML | 2018 |
216 | METAdiag | Detecting serious diseases due to abnormal cellular energetics | 2018 |
217 | MATURE-NK | MAnufacturing of TUmour-REactive Natural Killer cells | 2018 |
218 | Dyn-Syn-Mem | Dynamic mechanisms and functional roles of synaptic plasticity in memory | 2019 |
219 | IMMUNEDIVERSITY | Defining of human adaptive immune gene diversity and its impact on disease | 2018 |
220 | AlloGPCR | Allosteric modulation of G-protein Coupled Receptors conformational landscape | 2018 |
221 | BASILIC | Decoding at systems-level the crosstalk between the T cell antigen receptor, the CD28 costimulator and the PD-1 coinhibitor under physiological and pathological conditions. | 2018 |
222 | SelectiveTGFb-inhib | Pro-tumorigenic effects of TGFb - elucidation of mechanisms and development of selective inhibitors | 2018 |
223 | CARAMBA | SLAMF7-CAR T cells prepared by Sleeping Beauty gene-transfer for immunotherapy of multiple myeloma – a rare hematologic disease | 2018 |
224 | DISCOVER | Death receptor signalling in tumour immune editing | 2018 |
225 | PAH-HOPE | New hope for the PAH patient: A Novel Therapeutic for Pulmonary Arterial Hypertension (PAH) | 2018 |
226 | CG01 | A novel gene therapy for epilepsy | 2018 |
227 | PCAPIP | Towards understanding non-canonical phosphatidylinositol kinases in the maintenance of prostate metabolism. | 2018 |
228 | Para-T System | The Para-T System A quick blood group device to match in situ the donor bag and the receptor arm during a blood transfusion, avoiding major incompatible errors. | 2018 |
229 | LapIt | Making AML treatment a clinical reality: A novel anti-IL7 receptor antibody to deliver Lap to 5LO positive cells | 2019 |
230 | iGLURs - A NEW VIEW | Exposing nature’s view of ligand recognition in ionotropic glutamate receptors | 2019 |
231 | UNIFLUVAC | A novel universal influenza vaccine targeting epitopes of limited variability | 2018 |
232 | ActinSensor | Identification and characterization of a novel damage sensor for cytoskeletal proteins in Drosophila | 2019 |
233 | EPI-X4Health | Therapeutic potential of optimized derivatives of an endogenous CXCR4 antagonist for the treatment of cancers and inflammatory diseases | 2018 |
234 | DYNACEUTICS | Remote control healing: Next generation mechano-nano-therapeutics | 2019 |
235 | Sugar-Enable | Influenza Virus - Sugar Interactions, From Glycan Arrays To Better Vaccines | 2018 |
236 | T-REX | Developing healthy crops for EU: T3SS-Recognition EXploration (T-REX) for plant immunity against bacteria | 2019 |
237 | LeukemiaEnviron | SIGNALING PROPENSITY IN THE MICROENVIRONMENT OF B CELL CHRONIC LYMPHOCYTIC LEUKEMIA | 2019 |
238 | ERGO | Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation | 2019 |
239 | IM2PACT | Investigating Mechanisms and Models Predictive of Accessibility of Therapeutics (IM2PACT) Into The Brain | 2019 |
240 | TIL-FIT | Increasing the fitness of tumor-infiltrating T cells for cellular immunotherapy | 2019 |
241 | SINSTRO | Unique approach to improving neurological function after stroke with SIN020 | 2019 |
242 | IMMCEPTION | Nociception and sensory nerves as regulators of type 2 immunity and skin inflammation | 2019 |
243 | TCRabX | Structural basis for the therapeutic efficiency of optimal-affinity T cell receptors | 2019 |
244 | SEPSCAV | SCAVENGING ON SEPSIS. DEVELOPMENT OF SEPSIS SPECIFIC DRUGS FROM HUMAN SCAVENGER RECEPTORS | 2019 |
245 | XEND | Clinical assessment of PILA PHARMA’s TRPV1 antagonist, XEN-D0501, as a novel type of oral anti-diabetic agent | 2019 |
246 | ENTRI | Enteric-nervous-system-mediated regulation of intestinal inflammation | 2019 |
247 | iHEAR | Gene therapy of inherited and acquired hearing loss | 2019 |
248 | Lakhesys | Lakhesys: building the machine to make the medicines of tomorrow | 2019 |
249 | NovelNMDA | Novel NMDA receptor signaling in cortical synaptic depression | 2019 |
250 | skILL | Intracellular signalling by modified lipopolysaccharide | 2019 |
251 | iReceptor Plus | ARCHITECTURE AND TOOLS FOR THE QUERY OF ANTIBODY AND T-CELL RECEPTOR SEQUENCING DATA REPOSITORIES FOR ENABLING IMPROVED PERSONALIZED MEDICINE AND IMMUNOTHERAPY | 2019 |
252 | SCAMPICITY | cAMP-dependend plasticity of striatal projection neurons in health and disease | 2019 |
253 | GLU-IMAGE | Glutamate dynamics during visual stimulation and ketamine challenge in the human brain | 2019 |
254 | Biosensor Design | Engineering Chemotactic Biosensors for a Diverse Spectrum of Metastatic Markers | 2020 |
255 | R-FunSel | In vivo functional screening via CRISPR-Cas9 to systematically identify cardiomyocyte receptors as targets for the innovative therapies for myocardial infarction and heart failure | 2019 |
256 | TaPPiNG-EPI | Targeting Purinergic Pathway in drug-resistant epilepsy using human Neurons and Glia. | 2019 |
257 | IMPACT | Immune Mechanisms of Necrotic DNA Phagocytosis by Neutrophils: A Role for Integrins | 2020 |
258 | EOBRECA | Differential Roles of Estrogens in Obesity-mediated ER+ Breast Cancer Development | 2019 |
259 | PCinBC | Plasma cell heterogeneity and dynamics in patient tumors | 2019 |
260 | TLRstorm | Spatial and temporal control of self/non-self discrimination in innate immunity | 2019 |
261 | AR-DDR | Co-targeting androgen receptor signalling and DNA damage repair for precision therapy in advanced prostate cancer | 2019 |
262 | RAMEN | RAMan spectroscopy for tracking Exosome based delivery of Nutraceuticals | 2019 |
263 | PullEd-MS | Finding unknown endocrine disrupting compounds through target pull-down assay filtration, effect direct analysis and ultra-high resolution mass spectrometry for a comprehensive efficient workflow. | 2019 |
264 | ASTRALIS | ASTRocyte Adrenoceptors: Light on Intracellular Signaling | 2019 |
265 | IEOCCD | THE IMPACT OF THE ENVIRONMENT AND ONCOGENESIS ON CANCER CELL DIVISIONS | 2019 |
266 | MGLycan | Targeting hMGL-GalNAc interactions to reverse immune suppression in cancer | 2019 |
267 | CatchGel | Catch Bond Cross-linked Hydrogels | 2020 |
268 | MDR | Structural and functional characterization of MAVS-DDX3-vRNA complex | 2019 |
269 | MINT | Multifunctional Immunocompatible NanoTheranostics to modulate tumor microenvironment and improve treatment monitoring: A double blow to pancreatic cancer | 2019 |
270 | PD-MIND | Parkinson Disease with Mild cognition Impairment treated with Nicotinic agonist Drug | 2019 |
271 | STOPFOP | Saracatinib Trial tO Prevent FOP | 2019 |
272 | ImmUne | Towards identification of the unifying principles of vertebrate adaptive immunity | 2019 |
273 | MIMIC | Mapping and modulating integrin mediated interactions | 2020 |
274 | MIMIC | Deciphering how microbiota modulate anti-tumor immune responses in checkpoint therapy | 2020 |
275 | signalling dynamics | Bridging biophysics and cell biology: The role of G protein-coupled receptor conformations in signalling | 2020 |
276 | LongPlaNet | Long-Range Plasticity of Neuronal Networks in the Adult Brain | 2019 |
277 | HighResCells | A synergistic approach toward understanding receptor signaling in the cell at very high resolution | 2019 |
278 | SUPRA2DMAT | Supramolecular engineering of multifunctional systems and devices: the molecular approach to 2D materials | 2019 |
279 | Metabinnate | Metabolic crosstalk in the regulation of inflammation | 2019 |
280 | Sperm-Egg Phusion | Unexpected connections between a phagocytic machinery and mammalian fertilization | 2019 |
281 | SCOPE | Schwann Cell Options for chronic Pain Eradication | 2019 |
282 | GPCR Transcriptomics | Exploring the role of GPCR expression diversity in receptor physiology and drug response | 2019 |
283 | NeoPur | New treatments and novel diagnostic tests for neonatal seizures based on purinergic signaling. | 2019 |
284 | PhotoXLink | Development of biomolecular tools for the spatiotemporal photocontrol of AMPA receptors mobility | 2019 |
285 | UNPACK PD-L1 | Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells | 2020 |
286 | Hepatic Thermogenesi | Study the functions of the hepatic sympathetic nerve and the receptor Adrb3 in liver-mediated adaptive thermogenesis. | 2019 |
287 | SCHENGEN-ROOT | 'Filling the gaps' in the Schengen pathway for plant root Casparian strip integrity | 2020 |
288 | INTERGLP1 | Dissecting GLP-1 receptor internalization pathways using genetic and pharmacological tools | 2020 |
289 | T-NHL SUPRESSORS | Tumor suppressor pathways counteracting oncogenic immune receptor signaling in T-Cell Lymphoma | 2019 |
290 | RetinDR | RetinDR: The first topical ophthalmic formulation (eye drops) that effectively prevents and/or treats the retinal neurodegeneration induced by diabetes (diabetic retinopathy) and/or aging | 2019 |
291 | TRACER | TRAF-STOP therapy to reduCe inflammation in athERosclerosis. | 2020 |
292 | MechanoGPER | Development of GPER agonists as a novel therapeutic option for pancreatic cancer | 2019 |
293 | GLYCOSWITCH | Probing the mysteries of sweet “on-off” switches of the human immune system: toward the development of novel glycomimetics against bacterial infections | 2020 |
294 | IMMUNE | Investigation into the Molecular Mechanisms Underlying NEmatode recognition by the Ma resistance protein in perennial plum roots | 2019 |
295 | B-DOMINANCE | B Cell Immunodominance in Antiviral Immunity | 2019 |
296 | SYNVIVO | Revealing dendritic cell-CD4+ T cell communication by using synthetic biology in vivo | 2020 |
297 | NeuroPa | Targeting the brain sigma-1 receptor: A paradigm shift for the treatment of neuro-degenerative disorders | 2019 |
298 | Bac2MUC | Bacteria-mucin interactions – Shaping intestinal epithelial responses in health and disease | 2020 |
299 | PANDORA | Pandemics Outbreaks Rationalized: towards a universal therapy to eliminate intracellular pathogens and drug resistance | 2020 |
300 | CLAUSTROFUNCT | Claustrum function in cortical processing and putative claustral dysfunction in schizophrenia | 2020 |
301 | Meta-Targeting | Macro-Nanomedicine to Treat Metastatic Cancer | 2020 |
302 | PDPcardio | Protein phosphatase 1-disrupting peptides: Scope and mechanism of action in the treatment of heart insufficiency | 2020 |
303 | POST-IT | Pathogen Oriented SNARE Trafficking for Immune Tailoring | 2020 |
304 | Controlling MAC | Structural basis of controlling the membrane attack complex | 2020 |
305 | H I C I | Transcriptional and epigenetic control of tissue regenerative HB-EGF in autoimmune CNS inflammation | 2020 |
306 | PreSynPlast | Molecular mechanisms of presynaptic plasticity | 2020 |
307 | QS21-Mech | Target identification and elucidation of the molecular mechanism of action of saponin vaccine adjuvants QS-21 (QS21Mech) | 2020 |
308 | SERWOM | Understanding Serotonergic Regulation of Working Memory | 2020 |
309 | C.A.R.E. OA | Cross-linking Adenosine Receptors - Estrogen receptors for OA treatment | 2021 |
310 | ParkIFNAR | Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context. | 2020 |
311 | Turbo-MPMI-Discovery | TurboID-charging discovery of plant pathogen virulence and host resistance mechanisms | 2020 |
312 | Tac1-Ovulation | Addressing the Roles of Tachykinins in the Control of Ovulation: Focus on the Substance-P/Tachykinin Receptor Type 1 (Tac1/Tacr1) System | 2020 |
313 | NetriCan | Characterization of the role of netrin-1 in the regulation of the Epithelial-to-Mesenchymal Transition during tumor progression. | 2020 |
314 | MITafterVIT | Unravelling maintenance mechanisms of immune tolerance after termination of venom immunotherapy by means of clonal mast cell diseases | 2020 |
315 | NANOCRISPR | NANODELIVERY OF SPECIFIC GENOME ENGINEERING TOOLS AS A NOVEL THERAPEUTIC APPROACH FOR AGGRESSIVE PROSTATE CANCERS | 2021 |
316 | TARNEPC | Targeting treatment-induced neuroendocrine prostate cancer | 2021 |
317 | LAMININ | Light-switchable proteins and Adhesion Micropatterns to Illuminate the Navigation machInery of Neurons | 2020 |
318 | DEFINE | DEciphering mechanisms of presynaptic reFINEment | 2020 |
319 | RENOPROTECT | Targeting tubular reabsorption for kidney protection | 2020 |
320 | MANTARGET | Super resolution imaging of nanoPMOs for cancer drug delivery | 2021 |
321 | PIANISM | Prefrontal Cortex Circuit Dynamics underlying Working Memory and its Serotonin Modulation | 2020 |
322 | FUSION | Single Molecule Imaging-based design of HIV-1 vaccines | 2020 |
323 | ICG68-PROG | Imaging of c-Met aberrant cancers with Gallium-68 chelators for positron emission tomography | 2020 |
324 | ROSETTA | Deciphering the Role of aberrant glycOSylation in the rEsponse to Targeted TherApies for breast cancer | 2020 |
325 | GABARPET | ImmunoPET directed to specific subtypes of GABAA receptors as strategy for molecular mapping of behaviour and mental illness | 2020 |
326 | HT4PD | The role of the serotonin 5-HT4 receptor in motor and non-motor symptoms of Parkinson’s disease | 2021 |