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DEMO SIGNED

Dementia modelling

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

DEMO project word cloud

Explore the words cloud of the DEMO project. It provides you a very rough idea of what is the project "DEMO" about.

framework clinical fdg av45 patients doctoral innovative spend glucose phd cdt relatives studentships perfusion denmark purpose abnormalities professional ad guidance pathologies university biomediq cmic vascular drc brain modeling constitutes model centre morphology flair vad mri enrolled quantitative supervision copenhagen disease white stage pathological accumulation medical computational dementia turnover college monetary pet imaging dwi majority burden structural maximum industry biomarkers ucl suffering etiology final collaborators network proteins construct london pib alzheimer epsrc cohort researcher society create t2 time training quantification image t1 computing asl facilities students diseases exposed

Project "DEMO" data sheet

The following table provides information about the project.

Coordinator	BIOMEDIQ AS Organization address address: FRUEBJERGVEJ 3 city: KOBENHAVN postcode: 2100 website: www.biomediq.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Denmark [DK]
Project website	http://dementia-modelling.eu/
Total cost	853˙451 €
EC max contribution	853˙451 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2016
Funding Scheme	MSCA-ITN-EID
Starting year	2016
Duration (year-month-day)	from 2016-09-01 to 2020-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	BIOMEDIQ AS BIOMEDIQ AS Organization address address: FRUEBJERGVEJ 3 city: KOBENHAVN postcode: 2100 website: www.biomediq.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KOBENHAVN)	coordinator	580˙163.00
2	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	142˙717.00
3	KING'S COLLEGE LONDON KING'S COLLEGE LONDON Organization address address: STRAND city: LONDON postcode: WC2R 2LS website: www.kcl.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	130˙570.00

Map

Project objective

Dementia constitutes a major burden on society, both in monetary costs and the suffering of patients and their relatives. It comprises a number of diseases including Alzheimer’s disease (AD) and vascular dementia (VaD). In recent years, imaging biomarkers have been developed including measures of brain morphology (MRI T1), vascular pathologies (MRI T2*/FLAIR), white matter abnormalities (MRI DWI), perfusion (MRI ASL), glucose turnover (PET FDG), and accumulation of pathological proteins (PET PIB/AV45). Quantitative measures using these biomarkers in large cohort studies have the potential to model the pathological process of the disease. This proposal would create an innovative training network, in which early stage researchers will develop new computational imaging biomarkers, under the supervision of experienced researchers, for the purpose of modeling dementia etiology. One researcher will investigate quantification of vascular pathologies, another will develop quantitative measures of white matter abnormalities from structural MRI, and the final researcher will construct a quantitative model of disease etiology using a maximum-likelihood framework. The early stage researchers will be enrolled as PhD students at University College London (UCL) under the EPSRC Centre for Doctoral Training in Medical Imaging (CDT), which is based in Centre for Medical Image Computing (CMIC), with the Dementia Research Centre (DRC) being one of the main clinical collaborators for CDT studentships. However, they will spend the majority of time at the research facilities of Biomediq A/S, Copenhagen Denmark, where they will be exposed to industry and work under professional guidance.

Deliverables

List of deliverables.
Recruitment completed	Other	2019-07-24 11:09:15
Webpage completion	Websites, patent fillings, videos etc.	2019-07-18 19:26:50

Take a look to the deliverables list in detail: detailed list of DEMO deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Mostafa Mehdipour Ghazi, Mads Nielsen, Akshay Pai, M. Jorge Cardoso, Marc Modat, SÃ©bastien Ourselin, Lauge SÃ¸rensen Training recurrent neural networks robust to incomplete data: Application to Alzheimerâ€™s disease progression modeling published pages: 39-46, ISSN: 1361-8415, DOI: 10.1016/j.media.2019.01.004	Medical Image Analysis 53	2019-10-08
2018	Mostafa Mehdipour Ghazi, Mads Nielsen, Akshay Pai, M. Jorge Cardoso, Marc Modat, Sebastien Ourselin, Lauge SÃ¸rensen Robust training of recurrent neural networks to handle missing data for disease progression modeling published pages: , ISSN: 2331-8422, DOI:	1st International Conference on Medical Imaging with Deep Learning (MIDL)	2019-07-18
2018	Mauricio Orbes-Arteaga, Lauge SÃ¸rensen, Marc Modat, M. Jorge Cardoso, SÃ©bastien Ourselin, Mads Nielsen, Akshay Pai Simultaneous synthesis of FLAIR and segmentation of white matter hypointensities from T1 MRIs published pages: , ISSN: 2331-8422, DOI:	1st International conference on Medical Imaging with Deep Learning (MIDL)	2019-07-18

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The information about "DEMO" are provided by the European Opendata Portal: CORDIS opendata.