Opendata, web and dolomites

MultimodalCellTrack SIGNED

Multimodal preclinical imaging probes to evaluate the safety and efficacy of regenerative medicine therapies

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MultimodalCellTrack project word cloud

Explore the words cloud of the MultimodalCellTrack project. It provides you a very rough idea of what is the project "MultimodalCellTrack" about.

place    engrafted    humboldt    resonance    brings    temporal    therapies    anatomical    combine    cellular    safety    organ    nano    she    host    functional    hub    imaging    ameliorate    micro    single    building    modalities    platform    efficacy    technologies    organs    multimodal    biodistribution    functionalization    time    centre    labelling    liverpool    supervisory    photoacoustic    accurately    synthesis    monitor    preclinical    spatial    gained    suite    sumaira    members    resolution    proportion    live    university    team    regenerative    cells    ashraf    irshad    barrier    monitoring    probes    monitored    sensitivity    wolfgang    particles    magnetophoresis    parak    mri    mouse    effect    magnetic    provides    technique    transplanted    injury    medicine    inability    assembly    germany    prepare    assessing    inaugurated    adverse    our    optimize    hussain    persist    tissues    phd    models    ukrmp    pakistan    cell    uk    bioluminescence    fellowship   

Project "MultimodalCellTrack" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF LIVERPOOL 

Organization address
address: BROWNLOW HILL 765 FOUNDATION BUILDING
city: LIVERPOOL
postcode: L69 7ZX
website: www.liverpool.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-08-01   to  2018-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) coordinator 183˙454.00

Map

 Project objective

Our inability to accurately monitor the biodistribution of transplanted cells is a major barrier to assessing the safety and efficacy of cell-based regenerative medicine therapies. To assess safety, it is important to know if cells have engrafted into non-target organs so that possible adverse effects can be monitored over time; and to assess efficacy, it is crucial to know what proportion of cells reach the target organ, for how long they persist, and whether they ameliorate injury. Various imaging technologies, including magnetic resonance imaging (MRI), bioluminescence imaging and photoacoustic imaging can be used for monitoring cellular biodistribution and assessing the effect of the cells on host organs and tissues, but no single technique provides high sensitivity, spatial and temporal resolution, and functional and anatomical imaging. It is therefore necessary to combine several imaging approaches.

The University of Liverpool is leading the UK Regenerative Medicine Platform Safety and Efficacy Hub. The hub includes all members of the supervisory team. The University has just inaugurated its new centre for preclinical imaging which brings together in a single place a unique suite of state of the art imaging modalities (including high field MRI and photoacoustic imaging).

Building on her wide experience in the synthesis, functionalization and assembly of nano/micro-particles gained during her PhD with Irshad Hussain (Pakistan) and a Humboldt Fellowship with Wolfgang Parak (Germany), Sumaira Ashraf (the applicant) will prepare probes tailored for cell labelling and multimodal imaging. She will evaluate and optimize the properties of the probes following cell uptake (live cell imaging, magnetophoresis, etc) and finally test the most promising multimodal probes in mouse models of injury that are established within the UKRMP hub.

 Publications

year authors and title journal last update
List of publications.
2018 Sumaira Ashraf, Arthur Taylor, Jack Sharkey, Michael Barrow, Patricia Murray, Bettina Wilm, Harish Poptani, Matthew J. Rosseinsky, Dave Adams and Raphael Levy
In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells
published pages: , ISSN: 2516-0230, DOI: 10.1039/c8na00098k
Nanoscale advances Monthly 2019-06-13
2017 Sumaira Ashraf, Michael Barrow, Arthur Taylor, Jack Sharkey, Patricia Murray, Bettina Wilm, Harish Poptani, Matthew Rosseinsky, & Raphaël Lévy
Multimodal Colloidal Imaging Probes
published pages: , ISSN: , DOI:
Centre for Preclinical Imaging – 3rd Annual Symposium 3rd Annual Symposium 2019-06-13
2017 Sumaira Ashraf
AT THE 254TH ACS CONFERENCE IN WASHINGTON DC
published pages: , ISSN: , DOI:
Blog post 2019-06-13
2017 Sumaira Ashraf, Michael Barrow, Joan Comenge, Arthur Taylor, Jack Sharkey, Patricia Murray, Bettina Wilm, Antonius Plagge, Harish Poptani, Matthew Rosseinsky, Raphael Levy
Multimodal stem cell imaging and tracking
published pages: , ISSN: , DOI:
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254 2019-06-13
2017 Sumaira Ashraf, Michael Barrow, Joan Comenge, Arthur Taylor, Jack Sharkey, Patricia Murray, Bettina Wilm, Harish Poptani, Matthew Rosseinsky, & Raphaël Lévy
Multimodal Colloidal Imaging Probes for Cell Tracking
published pages: , ISSN: , DOI:
Northern Postdoctoral Researcher Meeting 3 3 2019-06-13

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MULTIMODALCELLTRACK" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MULTIMODALCELLTRACK" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

PmNC (2019)

Policy-making of early nature conservation. The Netherlands and the United Kingdom compared, 1930-1960

Read More  

TheaTheor (2018)

Theorizing the Production of 'Comedia Nueva': The Process of Play Configuration in Spanish Golden Age Theater

Read More  

InBPSOC (2020)

Increases biomass production and soil organic carbon stocks with innovative cropping systems under climate change

Read More