Explore the words cloud of the MAGNAMED project. It provides you a very rough idea of what is the project "MAGNAMED" about.
The following table provides information about the project.
Coordinator |
UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA
Organization address contact info |
Coordinator Country | Spain [ES] |
Total cost | 846˙000 € |
EC max contribution | 846˙000 € (100%) |
Programme |
1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge) |
Code Call | H2020-MSCA-RISE-2016 |
Funding Scheme | MSCA-RISE |
Starting year | 2017 |
Duration (year-month-day) | from 2017-04-01 to 2021-03-31 |
Take a look of project's partnership.
MAGNAMED designs, fabricates, and assesses novel magnetic nanostructures (MNS) with unique spin configurations for innovative diagnostics and therapy techniques. An early stage detection and an effective treatment are keystones to reduce cancer mortality. Current clinical procedures fail to detect small concentration of tumoral biomarkers. Magnetic nanoparticles (MNP), like beads, have attracted much attention for their capability to improve cancer detection limits and treatment technologies. However, there are several limitations to the use of MNP. As an emerging alternative, MNS are being explored. Unlike MNP, MNS (e.g. nanodisks) present a planar shape with novel properties for diagnosis: high magnetic moment and large size, which can significantly improve the sensor sensitivity, and for therapy: due to their planar shape, alternate magnetic fields provoke a magneto-mechanical action on the cell membrane that triggers cell death. The efficiency of MNS in these two medical applications has not been investigated yet for MNS at the nanometer scale. The challenge of this project is to produce MNS with nanometer dimensions suitable for medical applications. Several lithography techniques will be used to fabricate MNS in vortex and antiferromagnetic spin configurations covering a broad size range (40 to 4000 nm). After functionalization, MNS will be exploited in: (i) Diagnostics, using giant magnetoresistance (GMR) sensors for the detection of tumoral biomarkers (dermcidin and carcinoembryonic antigen), and (ii) Therapy, effectiveness of tumoral cell annihilation by the magneto-mechanical action of MNS will be evaluated in vitro assays of melanoma and colorectal cancer cells. MAGNAMED is a cross-sectoral and interdisciplinary project involving Physics, Chemistry and Medicine. Findings will have a medium-term impact on the European strategy for early stage detection of cancer and a long-term impact on the development of novel and groundbreaking therapeutics techniques.
year | authors and title | journal | last update |
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2018 |
MarÃa Francisca Matus, Cristian Vilos, Bruno A. Cisterna, Eduardo Fuentes, Iván Palomo Nanotechnology and primary hemostasis: Differential effects of nanoparticles on platelet responses published pages: 1-8, ISSN: 1537-1891, DOI: 10.1016/j.vph.2017.11.004 |
Vascular Pharmacology 101 | 2019-09-02 |
2018 |
Eduardo Ortega, Beatriz Mora, Carlos Monton, Carolina Redondo, Josefina Arellano, Rafael Morales, Edgar Voelkl, Arturo Ponce Study of Vortex State in Permalloy Plates Using Optimized Electron Holography published pages: 952-953, ISSN: 1431-9276, DOI: 10.1017/s1431927618005251 |
Microscopy and Microanalysis 24/S1 | 2019-09-02 |
2017 |
Felipe Torres, Rafael Morales, Ivan K. Schuller, Miguel Kiwi Dipole-induced exchange bias published pages: 17074-17079, ISSN: 2040-3364, DOI: 10.1039/c7nr05491b |
Nanoscale 9/43 | 2019-09-02 |
2018 |
Johanna Ãbrigo, Fabian Campos, Felipe Simon, Claudia Riedel, Daniel Cabrera, Cristian Vilos, Claudio Cabello-Verrugio TGF-β requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy published pages: 253-264, ISSN: 1431-6730, DOI: 10.1515/hsz-2017-0217 |
Biological Chemistry 399/3 | 2019-09-02 |
2019 |
Rita Soares, Verónica C. Martins, Rita Macedo, Filipe A. Cardoso, Sofia A. M. Martins, Diogo M. Caetano, Pedro H. Fonseca, Vânia Silvério, Susana Cardoso, Paulo P. Freitas Go with the flow: advances and trends in magnetic flow cytometry published pages: 1839-1862, ISSN: 1618-2642, DOI: 10.1007/s00216-019-01593-9 |
Analytical and Bioanalytical Chemistry 411/9 | 2019-09-02 |
2017 |
D. Navas, N. Soriano, F. Béron, C. T. Sousa, K. R. Pirota, J. Torrejon, C. Redondo, R. Morales, C. A. Ross Microscopic reversal magnetization mechanisms in CoCrPt thin films with perpendicular magnetic anisotropy: Fractal structure versus labyrinth stripe domains published pages: , ISSN: 2469-9950, DOI: 10.1103/physrevb.96.180403 |
Physical Review B 96/18 | 2019-09-02 |
2018 |
Beatriz Mora, Arantza Perez-Valle, Carolina Redondo, Maria Dolores Boyano, Rafael Morales Cost-Effective Design of High-Magnetic Moment Nanostructures for Biotechnological Applications published pages: 8165-8172, ISSN: 1944-8244, DOI: 10.1021/acsami.7b16779 |
ACS Applied Materials & Interfaces 10/9 | 2019-09-02 |
2019 |
A. S. Silva, A. Hierro-Rodriguez, S. A. Bunyaev, G. N. Kakazei, O. V. Dobrovolskiy, C. Redondo, R. Morales, H. Crespo, D. Navas Magnetic properties of permalloy antidot array fabricated by interference lithography published pages: 35136, ISSN: 2158-3226, DOI: 10.1063/1.5080111 |
AIP Advances 9/3 | 2019-09-02 |
2018 |
Abhishek Sahu, Youngmin Hwang, Cristian Vilos, Jong-Min Lim, Sunghyun Kim, Won Il Choi, Giyoong Tae A novel alendronate functionalized nanoprobe for simple colorimetric detection of cancer-associated hypercalcemia published pages: 13375-13383, ISSN: 2040-3364, DOI: 10.1039/c8nr02570c |
Nanoscale 10/28 | 2019-09-02 |
2017 |
Won Il Choi, Abhishek Sahu, Cristian Vilos, Nazila Kamaly, Seong-Min Jo, Jin Hyung Lee, Giyoong Tae Bioinspired Heparin Nanosponge Prepared by Photo-crosslinking for Controlled Release of Growth Factors published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-14040-5 |
Scientific Reports 7/1 | 2019-09-02 |
2018 |
MarÃa Francisca Matus, MartÃn Ludueña, Cristian Vilos, Iván Palomo, Marcelo M Mariscal Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules published pages: 1328-1338, ISSN: 2190-4286, DOI: 10.3762/bjnano.9.126 |
Beilstein Journal of Nanotechnology 9 | 2019-09-02 |
2018 |
Suellen Moraes, David Navas, Fanny Béron, Mariana Proenca, Kleber Pirota, Célia Sousa, João Araújo The Role of Cu Length on the Magnetic Behaviour of Fe/Cu Multi-Segmented Nanowires published pages: 490, ISSN: 2079-4991, DOI: 10.3390/nano8070490 |
Nanomaterials 8/7 | 2019-09-02 |
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