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Opendata, web and dolomites

ADOC SIGNED

Characterization and monitoring of vigilance fluctuation in disorders of consciousness

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

ADOC project word cloud

Explore the words cloud of the ADOC project. It provides you a very rough idea of what is the project "ADOC" about.

wakefulness population biomarkers behavioral stable recovery course patients tool periods exploratory fluctuation treat ocular pattern eeg time minimally diurnal marked suggesting consciousness assumption syndrome doc complexity scores unresponsive days revised display conscious neurophysiological vigilance understand characterizing responsiveness disorders bedside prospective monitoring coma

Project "ADOC" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITE DE LIEGE Organization address address: PLACE DU 20 AOUT 7 city: LIEGE postcode: 4000 website: www.ulg.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Belgium [BE]
Project website	http://www.gigacoma.uliege.be/cms/c_4255887/fr/portail-gigacoma
Total cost	160˙800 €
EC max contribution	160˙800 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2016
Funding Scheme	MSCA-IF-EF-ST
Starting year	2017
Duration (year-month-day)	from 2017-08-01 to 2019-11-10

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITE DE LIEGE UNIVERSITE DE LIEGE Organization address address: PLACE DU 20 AOUT 7 city: LIEGE postcode: 4000 website: www.ulg.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LIEGE)	coordinator	160˙800.00

Map

Project objective

This prospective exploratory study will aim at characterizing vigilance fluctuation in patients with disorders of consciousness (as defined by a change in diurnal behavioral response over time) using neurophysiological parameters. We based this project on the assumption that changes at the Coma Recovery Scale-Revised scores (i.e., behavioral responsiveness) will be associated with a change in ocular measures and EEG complexity, suggesting that some of these parameters could be used for monitoring vigilance in this population. We expect that this fluctuation will be particularly marked in patients with a minimally conscious state as compared with patients in an unresponsive wakefulness syndrome who will display a more stable pattern of response over the two days. This project aims to better understand the course of vigilance fluctuation in DOC and to develop an objective tool based on biomarkers that could be used at bedside to determine the best periods to assess and treat these patients.

Publications

List of publications.
year	authors and title	journal	last update
2018	Chatelle C, Thibaut A, Gosseries O, Cassol H, Aubinet C, CarriÃ¨re M, Wolff A, Martens G, Barra A, Martial C, Blandiaux S, Wannez S, Charland-Verville V, Laureys S. Fluctuation in behavioral responsiveness in severely brain-injured patients published pages: 90â€“276, ISSN: 1351-5101, DOI:	European Journal of Neurology 25	2020-04-09
2019	Mortaheb S, Bonin E, Laureys S, Chatelle C. Pupil diameter and Behavioral Responsiveness in Disorders of Consciousness published pages: (Suppl. 33) 189-, ISSN: , DOI:	Brain Injury	2020-04-09

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The information about "ADOC" are provided by the European Opendata Portal: CORDIS opendata.