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RHAPSODY SIGNED

Assessing risk and progression of prediabetes and type 2 diabetes to enable disease modification - Sofia ref.: 115881

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

RHAPSODY project word cloud

Explore the words cloud of the RHAPSODY project. It provides you a very rough idea of what is the project "RHAPSODY" about.

federation longitudinal physiological cohorts plans organs strategies establishment combine approval validate progression biomarkers pharmaceutical data clinical samples approaches datasets health experts segmentation goals trial prevention patient prominent experimental engagement worldwide maps adoption imi1 molecular regulatory epigenetic t2d treatment expertise discovery mellitus paths causal rhapsody taxonomy diabetes omic tissues biology stated economics precision leaders medicine subtypes biochemical genetic inform

Project "RHAPSODY" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITE DE LAUSANNE Organization address address: Quartier Unil-Centre Bâtiment Unicentre city: LAUSANNE postcode: 1015 website: www.unil.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Switzerland [CH]
Project website	http://www.imi-rhapsody.eu/
Total cost	18˙488˙749 €
EC max contribution	8˙130˙000 € (44%)
Programme	1. H2020-EU.3.1.7. (Innovative Medicines Initiative 2 (IMI2))
Code Call	H2020-JTI-IMI2-2015-03-two-stage
Funding Scheme	IMI2-RIA
Starting year	2016
Duration (year-month-day)	from 2016-04-01 to 2020-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITE DE LAUSANNE UNIVERSITE DE LAUSANNE Organization address address: Quartier Unil-Centre Bâtiment Unicentre city: LAUSANNE postcode: 1015 website: www.unil.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (LAUSANNE)	coordinator	0.00
2	LUNDS UNIVERSITET LUNDS UNIVERSITET Organization address address: Paradisgatan 5c city: LUND postcode: 22100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (LUND)	participant	1˙071˙853.00
3	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	748˙130.00
4	KOBENHAVNS UNIVERSITET KOBENHAVNS UNIVERSITET Organization address address: NORREGADE 10 city: KOBENHAVN postcode: 1165 website: www.ku.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KOBENHAVN)	participant	599˙151.00
5	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	518˙741.00
6	TECHNISCHE UNIVERSITAET DRESDEN TECHNISCHE UNIVERSITAET DRESDEN Organization address address: HELMHOLTZSTRASSE 10 city: DRESDEN postcode: 1069 website: http://www.tu-dresden.de/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (DRESDEN)	participant	518˙723.00
7	UNIVERSITY OF DUNDEE UNIVERSITY OF DUNDEE Organization address address: Nethergate city: DUNDEE postcode: DD1 4HN website: www.dundee.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (DUNDEE)	participant	499˙121.00
8	ITA-SUOMEN YLIOPISTO ITA-SUOMEN YLIOPISTO Organization address address: YLIOPISTONRANTA 1 E city: KUOPIO postcode: 70211 website: www.uef.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (KUOPIO)	participant	472˙587.00
9	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	468˙923.00
10	UNIVERSITE DE PARIS UNIVERSITE DE PARIS Organization address address: 85 BD SAINT GERMAIN city: PARIS postcode: 75006 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	418˙970.00
11	LIPOTYPE LIPOTYPE Organization address address: TATZBERG 47 city: DRESDEN postcode: 1307 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (DRESDEN)	participant	418˙968.00
12	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	408˙745.00
13	UNIVERSITE LIBRE DE BRUXELLES UNIVERSITE LIBRE DE BRUXELLES Organization address address: AVENUE FRANKLIN ROOSEVELT 50 city: BRUXELLES postcode: 1050 website: www.ulb.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	participant	398˙395.00
14	EBERHARD KARLS UNIVERSITAET TUEBINGEN EBERHARD KARLS UNIVERSITAET TUEBINGEN Organization address address: GESCHWISTER-SCHOLL-PLATZ city: TUEBINGEN postcode: 72074 website: www.uni-tuebingen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (TUEBINGEN)	participant	389˙966.00
15	UNIVERSITA DI PISA UNIVERSITA DI PISA Organization address address: LUNGARNO PACINOTTI 43/44 city: PISA postcode: 56126 website: www.unipi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PISA)	participant	389˙043.00
16	CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE Organization address address: AVENUE OSCAR LAMBRET 2 city: LILLE postcode: 59037 website: http://www.chru-lille.fr/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (LILLE)	participant	299˙296.00
17	STICHTING VUMC STICHTING VUMC Organization address address: DE BOELELAAN 1117 city: AMSTERDAM postcode: 1081 HV website: www.vumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	149˙633.00
18	ACADEMISCH ZIEKENHUIS LEIDEN ACADEMISCH ZIEKENHUIS LEIDEN Organization address address: ALBINUSDREEF 2 city: LEIDEN postcode: 2333 ZA website: www.lumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (LEIDEN)	participant	149˙632.00
19	ACADEMISCH ZIEKENHUIS GRONINGEN ACADEMISCH ZIEKENHUIS GRONINGEN Organization address address: HANZEPLEIN 1 city: GRONINGEN postcode: 9713 GZ website: www.umcg.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (GRONINGEN)	participant	105˙380.00
20	AZIENDA OSPEDALIERA CITTA DELLA SALUTE E DELLA SCIENZA DI TORINO AZIENDA OSPEDALIERA CITTA DELLA SALUTE E DELLA SCIENZA DI TORINO Organization address address: CORSO BRAMANTE 88 90 city: TORINO postcode: 10126 website: www.cittadellasalute.to.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (TORINO)	participant	104˙743.00
21	Eli Lilly and Company Limited Eli Lilly and Company Limited Organization address address: Lilly House, Priestley Road city: Basingstoke postcode: RG24 9NL website: www.lilly.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Basingstoke)	participant	0.00
22	INSTITUT DE RECHERCHES SERVIER INSTITUT DE RECHERCHES SERVIER Organization address address: 3 Rue de la Republique city: SURESNES postcode: 92150 website: www.servier.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (SURESNES)	participant	0.00
23	JANSSEN PHARMACEUTICA NV JANSSEN PHARMACEUTICA NV Organization address address: TURNHOUTSEWEG 30 city: BEERSE postcode: 2340 website: www.janssenpharmaceutica.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BEERSE)	participant	0.00
24	NOVO NORDISK A/S NOVO NORDISK A/S Organization address address: NOVO ALLE 1 city: BAGSVAERD postcode: 2880 website: www.novonordisk.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (BAGSVAERD)	participant	0.00
25	SANOFI-AVENTIS DEUTSCHLAND GMBH SANOFI-AVENTIS DEUTSCHLAND GMBH Organization address address: BRUNINGSTRASSE 50 city: FRANKFURT AM MAIN postcode: 65929 website: www.sanofi.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (FRANKFURT AM MAIN)	participant	0.00
26	SCIPROM SARL SCIPROM SARL Organization address address: RUE DU CENTRE 70 city: SAINT SULPICE postcode: 1025 website: http://www.sciprom.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (SAINT SULPICE)	participant	0.00
27	SIB INSTITUT SUISSE DE BIOINFORMATIQUE SIB INSTITUT SUISSE DE BIOINFORMATIQUE Organization address address: RUE MICHEL SERVET 1 CMU city: GENEVE postcode: 1206 website: www.isb-sib.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVE)	participant	0.00
28	UNIVERSITE PARIS DIDEROT - PARIS 7 UNIVERSITE PARIS DIDEROT - PARIS 7 Organization address address: RUE THOMAS MANN 5 city: PARIS postcode: 75205 website: www.univ-paris-diderot.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	0.00

Map

Project objective

The stated goal of RHAPSODY is to define a molecular taxonomy of type 2 diabetes mellitus (T2D) that will support patient segmentation, inform clinical trial design, and the establishment of regulatory paths for the adoption of novel strategies for diabetes prevention and treatment. To address these goals, RHAPSODY will bring together prominent European experts, including the leaders of the diabetes-relevant IMI1 projects to identify, validate and characterize causal biomarkers for T2D subtypes and progression. Our plans are built upon: (a) access to large European cohorts with comprehensive genetic analyses and rich longitudinal clinical and biochemical data and samplesÍ¾ (b) detailed multi-omic maps of key T2D-relevant tissues and organsÍ¾ (c) large expertise in the development and use of novel genetic, epigenetic, biochemical and physiological experimental approachesÍ¾ (d) the ability to combine existing and novel data sets through effective data federation and use of these datasets in systems biology approaches towards precision medicineÍ¾ and (e) expertise in regulatory approval, health economics and patient engagement. These activities will lead to the discovery of novel biomarkers for improved T2D taxonomy, to support development of pharmaceutical activities, and for use in precision medicine to improve health in Europe and worldwide.

Deliverables

List of deliverables.
Assessment of insulin action and secretion in preclinical models	Documents, reports	2020-02-19 14:08:31
Project flyer	Websites, patent fillings, videos etc.	2020-02-19 14:08:31
Website	Websites, patent fillings, videos etc.	2020-02-19 14:08:31

Take a look to the deliverables list in detail: detailed list of RHAPSODY deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2020	Gaelle R. Carrat, Elizabeth Haythorne, Alejandra Tomas, Leena Haataja, Andreas MÃ¼ller, Peter Arvan, Alexandra Piunti, Kaiying Cheng, Mutian Huang, Timothy J. Pullen, Eleni Georgiadou, Theodoros Stylianides, Nur Shabrina Amirruddin, Victoria Salem, Walter Distaso, Andrew Cakebread, Kate J.Heesom, Philip A. Lewis, David J. Hodson, Linford J. Briant, Annie C.H. Fung, Richard B. Sessions, Fabien The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis published pages: , ISSN: , DOI: 10.1101/2020.03.25.007286		2020-04-24
2020	Thomas J. Clough, Nicoleta Baxan, Emma J. Coakley, Charlotte Rivas, Lan Zhao, Isabelle Leclerc, Aida Martinez-Sanchez, Guy A. Rutter, Nicholas J. Long Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of Î²-cell-dependent contrast enhancement in the pancreas published pages: 4732-4740, ISSN: 1477-9226, DOI: 10.1039/d0dt00332h	Dalton Transactions 49/15	2020-04-24
2020	Masaya Oshima, SÃ©verine Pechberty, Lara Bellini, Sven O. GÃ¶pel, MÃ©lanie Campana, Claude Rouch, Julien Dairou, Cristina Cosentino, Federica Fantuzzi, Sanna Toivonen, Piero Marchetti, Christophe Magnan, Miriam Cnop, HervÃ© Le Stunff, RaphaÃ«l Scharfmann Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity published pages: 395-409, ISSN: 0012-186X, DOI: 10.1007/s00125-019-05046-x	Diabetologia 63/2	2020-04-24
2019	Raphael Scharfmann, Willem Staels, Olivier Albagli The supply chain of human pancreatic Î² cell lines published pages: 3511-3520, ISSN: 0021-9738, DOI: 10.1172/jci129484	Journal of Clinical Investigation 129/9	2020-04-24
2020	Christopher Dumayne, David Tarussio, Ana Rodriguez Sanchez-Archidona, Alexandre Picard, Davide Basco, Xavier Pascal Berney, Mark Ibberson, Bernard Thorens Klf6 protects Î²-cells against insulin resistance-induced dedifferentiation published pages: 100958, ISSN: 2212-8778, DOI: 10.1016/j.molmet.2020.02.001	Molecular Metabolism 35	2020-04-24
2019	Victoria Salem, Luis Delgadillo Silva, Kinga Suba, Eleni Georgiadou, S. Neda Mousavy Gharavy, Nadeem Akhtar, Aldara Martin-Alonso, David C. A. Gaboriau, Stephen M. Rothery, Theodoros Stylianides, Gaelle Carrat, Timothy J. Pullen, Sumeet Pal Singh, David J. Hodson, Isabelle Leclerc, A. M. James Shapiro, Piero Marchetti, Linford J. B. Briant, Walter Distaso, Nikolay Ninov, Guy A. Rutter Leader Î²-cells coordinate Ca2+ dynamics across pancreatic islets in vivo published pages: 615-629, ISSN: 2522-5812, DOI: 10.1038/s42255-019-0075-2	Nature Metabolism 1/6	2020-04-24
2019	MickaÃ«l Canouil, Gerard A Bouland, AmÃ©lie Bonnefond, Philippe Froguel, Leen â€™t Hart, Roderick Slieker NACHO: a Nanostring nCounter data QC package published pages: , ISSN: 1367-4803, DOI: 10.1093/bioinformatics/btz647	Bioinformatics	2020-02-19
2019	Pamela L. Toledo, Juha M. Torkko, Andreas Mueller, Carolin Wegbrod, Anke SÃ¶nmez, Michele Solimena, Mario R. ErmÃ¡cora ICA512 RESP18 homology domain is a protein condensing factor and insulin fibrillation inhibitor published pages: 521351, ISSN: 0021-9258, DOI: 10.1101/521351	bioRxiv	2020-02-19
2018	Emma Ahlqvist, Petter Storm, Annemari KÃ¤rÃ¤jÃ¤mÃ¤ki, Mats Martinell, Mozhgan Dorkhan, Annelie Carlsson, Petter Vikman, Rashmi B Prasad, Dina Mansour Aly, Peter Almgren, Ylva Wessman, Nael Shaat, Peter SpÃ©gel, Hindrik Mulder, Eero Lindholm, Olle Melander, Ola Hansson, Ulf Malmqvist, Ã…ke Lernmark, Kaj Lahti, Tom ForsÃ©n, Tiinamaija Tuomi, Anders H Rosengren, Leif Groop Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables published pages: 361-369, ISSN: 2213-8587, DOI: 10.1016/s2213-8587(18)30051-2	The Lancet Diabetes & Endocrinology 6/5	2020-02-19
2019	Amna Khamis, MickaÃ«l Canouil, Afshan Siddiq, Hutokshi Crouch, Mario Falchi, Manon von Bulow, Florian Ehehalt, Lorella Marselli, Marius Distler, Daniela Richter, JÃ¼rgen Weitz, Krister Bokvist, Ioannis Xenarios, Bernard Thorens, Anke M. Schulte, Mark Ibberson, Amelie Bonnefond, Piero Marchetti, Michele Solimena, Philippe Froguel Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes published pages: , ISSN: 2212-8778, DOI: 10.1016/j.molmet.2019.03.004	Molecular Metabolism	2020-02-19
2019	Cristina Cosentino, Miriam Cnop, Mariana Igoillo-Esteve The tRNA epitranscriptome and diabetes: emergence of tRNA hypomodifications as a cause of pancreatic Î²-cell failure published pages: , ISSN: 1945-7170, DOI: 10.1210/en.2019-00098	Endocrinology	2020-02-19
2019	Jose Leal, Liam Mc Morrow, Waqar Khurshid, Eva Pagano, Talitha Feenstra Decision models of prediabetes populations: A systematic review published pages: , ISSN: 1462-8902, DOI: 10.1111/dom.13684	Diabetes, Obesity and Metabolism	2020-02-19
2017	Guy A. Rutter, David J. Hodson, Pauline Chabosseau, Elizabeth Haythorne, Timothy J. Pullen, Isabelle Leclerc Local and regional control of calcium dynamics in the pancreatic islet published pages: 30-41, ISSN: 1462-8902, DOI: 10.1111/dom.12990	Diabetes, Obesity and Metabolism 19	2020-02-19
2018	Cristina Cosentino, Sanna Toivonen, Esteban DiazÂ Villamil, Mohamed Atta, Jean-Luc Ravanat, StÃ©phane Demine, AndreaÂ Alex Schiavo, Nathalie Pachera, Jean-Philippe Deglasse, Jean-Christophe Jonas, Diego Balboa, Timo Otonkoski, Ewan R Pearson, Piero Marchetti, DÃ©cio L Eizirik, Miriam Cnop, Mariana Igoillo-Esteve Pancreatic Î²-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes published pages: 10302-10318, ISSN: 0305-1048, DOI: 10.1093/nar/gky839	Nucleic Acids Research 46/19	2020-02-19
2018	Felicia Gerst, Benjamin A Jaghutriz, Harald Staiger, Anke M Schulte, Estela Lorza-Gil, Gabriele Kaiser, Madhura Panse, Sieglinde Haug, Martin Heni, Monika SchÃ¼tz, Mandy Stadion, Annette SchÃ¼rmann, Flavia Marzetta, Mark Ibberson, Bence Sipos, Falko Fend, Thomas Fleming, Peter P Nawroth, Alfred KÃ¶nigsrainer, Silvio Nadalin, Silvia Wagner, Andreas Peter, Andreas Fritsche, Daniela Richter, Michele Solimena, Hans-Ulrich HÃ¤ring, Susanne Ullrich, Robert Wagner The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans published pages: 4373-4383, ISSN: 0021-972X, DOI: 10.1210/jc.2018-00791	The Journal of Clinical Endocrinology & Metabolism 103/12	2020-02-19
2018	Maria Lytrivi, Mariana Igoillo-Esteve, Miriam Cnop Inflammatory stress in islet Î²-cells: therapeutic implications for type 2 diabetes? published pages: 40-45, ISSN: 1471-4892, DOI: 10.1016/j.coph.2018.08.002	Current Opinion in Pharmacology 43	2020-02-19
2017	Mark I. McCarthy Painting a new picture of personalised medicine for diabetes published pages: 793-799, ISSN: 0012-186X, DOI: 10.1007/s00125-017-4210-x	Diabetologia 60/5	2020-02-19
2018	Rohit Babbar, Martin Heni, Andreas Peter, Martin HrabÄ› de Angelis, Hans-Ulrich HÃ¤ring, Andreas Fritsche, Hubert Preissl, Bernhard SchÃ¶lkopf, RÃ³bert Wagner Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test published pages: , ISSN: 1664-2392, DOI: 10.3389/fendo.2018.00082	Frontiers in Endocrinology 9	2020-02-19
2017	Paul W Franks, Alaitz Poveda Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy? published pages: 784-792, ISSN: 0012-186X, DOI: 10.1007/s00125-017-4207-5	Diabetologia 60/5	2020-02-19
2018	Paul Richards, Latif Rachdi, Masaya Oshima, Piero Marchetti, Marco Bugliani, Mathieu Armanet, Catherine Postic, Sandra Guilmeau, Raphael Scharfmann MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic Î²-Cells published pages: 461-472, ISSN: 0012-1797, DOI: 10.2337/db17-0595	Diabetes 67/3	2020-02-19
2018	Marc Diedisheim, Masaya Oshima, Olivier Albagli, Charlotte Wennberg Huldt, Ingela Ahlstedt, Maryam Clausen, Suraj Menon, Alexander Aivazidis, Anne-Christine Andreasson, William G. Haynes, Piero Marchetti, Lorella Marselli, Mathieu Armanet, Fabrice Chimienti, Raphael Scharfmann Modeling human pancreatic beta cell dedifferentiation published pages: 74-86, ISSN: 2212-8778, DOI: 10.1016/j.molmet.2018.02.002	Molecular Metabolism 10	2020-02-19
2017	Aida Martinez-Sanchez, Marie-Sophie Nguyen-Tu, Isabelle Leclerc, Guy A. Rutter Manipulation and Measurement of AMPK activity in pancreatic islets published pages: 413-431, ISSN: , DOI: 10.1007/978-1-4939-7598-3_26		2020-02-19
2017	Miriam Cnop, Sanna Toivonen, Mariana Igoillo-Esteve, Paraskevi Salpea Endoplasmic reticulum stress and eIF2Î± phosphorylation: The Achilles heel of pancreatic Î² cells published pages: 1024-1039, ISSN: 2212-8778, DOI: 10.1016/j.molmet.2017.06.001	Molecular Metabolism 6/9	2020-02-19
2017	Pascal M. Mutie, Giuseppe N. Giordano, Paul W. Franks Lifestyle precision medicine: the next generation in type 2 diabetes prevention? published pages: , ISSN: 1741-7015, DOI: 10.1186/s12916-017-0938-x	BMC Medicine 15/1	2020-02-19
2017	Jose Leal, Waqar Khurshid, Eva Pagano, Talitha Feenstra Computer simulation models of pre-diabetes populations: a systematic review protocol published pages: e014954, ISSN: 2044-6055, DOI: 10.1136/bmjopen-2016-014954	BMJ Open 7/10	2020-02-19
2018	Roderick C. Slieker, Amber A. W. A. van der Heijden, Nienke van Leeuwen, Hailiang Mei, Giel Nijpels, Joline W. J. Beulens, Leen M. â€™t Hart HbA1c is associated with altered expression in blood of cell cycle- and immune response-related genes published pages: 138-146, ISSN: 0012-186X, DOI: 10.1007/s00125-017-4467-0	Diabetologia 61/1	2020-02-19

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