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NANOSTEM SIGNED

New nanomaterials for neural stem cells drug delivery

Total Cost €

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EC-Contrib. €

0

Partnership

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 NANOSTEM project word cloud

Explore the words cloud of the NANOSTEM project. It provides you a very rough idea of what is the project "NANOSTEM" about.

formulations    nps    proliferation    permeation    pharmaceuticals    ranging    full    biology    therapeutic    pharmacology    personal    vivo    vitro    containing    distributed    sciences    expertise    regulation    nscs    skills    animal    wp    efficient    differentiate    synthesis    brings    14    organic    traumatic    brain    models    complemented    hospital    neuroscience    clinical    injuries    modern    chemistry    neurodegenerative    neurons    complementary    hypothesis    seven    polymer    evaluation    translation    nanostem    regenerative    computational    differentiation    nanoparticles    professional    nanomaterials    toxicity    efficacy    train    cell    packages    strategy    bbb    neural    scientific    wp3    esrs    academic    stroke    associate    total    cells    nanoparticle    wp2    groups    transport    entrepreneurship    training    nanobiotechnology    burden    migration    teams    characterization    diseases    biological    mayor    union    therapeutics    stem    interdisciplinary    team    uploading    industrial    tackle    society    wp1    six    combined    substantial    modeling   

Project "NANOSTEM" data sheet

The following table provides information about the project.

Coordinator
QUEEN MARY UNIVERSITY OF LONDON 

Organization address
address: 327 MILE END ROAD
city: LONDON
postcode: E1 4NS
website: http://www.qmul.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 3˙590˙354 €
 EC max contribution 3˙590˙354 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    QUEEN MARY UNIVERSITY OF LONDON UK (LONDON) coordinator 819˙863.00
2    CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO PT (COIMBRA) participant 715˙069.00
3    UNIVERSITE D'ARTOIS FR (ARRAS) participant 525˙751.00
4    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 273˙287.00
5    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 263˙659.00
6    UNIVERSITAET INNSBRUCK AT (INNSBRUCK) participant 255˙934.00
7    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH DE (NEUHERBERG) participant 249˙216.00
8    MJR PHARMJET GMBH DE (UBERHERRM) participant 249˙216.00
9    CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E. PT (COIMBRA) participant 238˙356.00
10    THE UNIVERSITY OF WARWICK UK (COVENTRY) participant 0.00
11    BRAINS FOR BRAIN FOUNDATION ONLUS IT (PADOVA) partner 0.00
12    HCS-Pharma FR (LOOS) partner 0.00
13    UNIVERSIDADE DE COIMBRA PT (COIMBRA) partner 0.00
14    UNIVERSITAT DES SAARLANDES DE (SAARBRUCKEN) partner 0.00

Map

 Project objective

Brain conditions such as neurodegenerative diseases, stroke and traumatic injuries are a mayor burden in modern society. Because neural stem cells (NSCs) can differentiate into new neural cells including neurons, the regulation of their proliferation, differentiation and migration represent a promising regenerative/therapeutic strategy. The hypothesis of NanoStem project is that novel nanoparticles (NPs) combined with recent identified/developed pharmaceuticals can be an efficient approach to control the biological activity of NSCs. The scientific project is organized in three work packages (WP), each focusing on specific objectives and containing well-defined deliverables. WP1 will focus on the synthesis of the nanomaterials and the uploading of the therapeutics. WP2 will take the best nanoparticles and focus more on the evaluation of the permeation and efficacy of the formulations against NSCs. WP3 will focus on in vivo studies to evaluate the formulations developed to tackle the brain and to assess their toxicity. The project will train 14 ESRs in areas including organic and polymer chemistry, cell biology, pharmacology, neuroscience, nanobiotechnology and clinical sciences. The project will also provide a substantial training program in complementary skills, targeting both professional and personal development, and translation of research and entrepreneurship. The project brings together six academic partners, one hospital and two industrial teams as full partners, complemented by four associate partners, one of which is an industrial team, distributed over a total of seven European Union member states. The consortium brings together groups with a very interdisciplinary expertise ranging from nanoparticle synthesis and characterization, computational modeling, in vitro BBB models and BBB transport, neural stem cells, animal testing and clinical expertise.

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The information about "NANOSTEM" are provided by the European Opendata Portal: CORDIS opendata.

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