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EURO SHOCK SIGNED

Testing the value of a novel strategic approach and its cost efficacy to improve the poor outcomes in Cardiogenic Shock

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

EURO SHOCK project word cloud

Explore the words cloud of the EURO SHOCK project. It provides you a very rough idea of what is the project "EURO SHOCK" about.

providers halt spiralling multidisciplinary extremely oxygenation versus delivering economic elderly suggests ecg mechanistic groups decline informing exists disease strategy spiral burden renowned therapeutic transfer efficacy recurrent morbidity physician statisticians death worse technologies rate trial guidelines significantly clear expensive risk phase3 12 unacceptably attack leave suffering mortality 4 chronic time clinical scientists pa extracorporeal core drugs cgs outcomes too admissions networks interventions females 42 cardiac alone health full shock patients 70 therapies heart incidence intervention life gt membrane ecmo framework economists attacks re medical europe unmet sick socio data randomised benefit care sme sub standard innovative true magnetic irrecoverable imaging specialised return ad resonance hoc ill protocols healthcare cardiogenic survivors reducing reduce

Project "EURO SHOCK" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY OF LEICESTER Organization address address: UNIVERSITY ROAD city: LEICESTER postcode: LE1 7RH website: www.le.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.euroshock-study.eu
Total cost	6˙499˙572 €
EC max contribution	6˙499˙572 € (100%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-SC1-2017-Two-Stage-RTD
Funding Scheme	RIA
Starting year	2018
Duration (year-month-day)	from 2018-01-01 to 2022-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY OF LEICESTER UNIVERSITY OF LEICESTER Organization address address: UNIVERSITY ROAD city: LEICESTER postcode: LE1 7RH website: www.le.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LEICESTER)	coordinator	946˙312.00
2	UNIVERSITY OF GLASGOW UNIVERSITY OF GLASGOW Organization address address: UNIVERSITY AVENUE city: GLASGOW postcode: G12 8QQ website: www.gla.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (GLASGOW)	participant	1˙327˙843.00
3	CHALICE MEDICAL LIMITED CHALICE MEDICAL LIMITED Organization address address: UNIT 1-2 DRAYTONVOURT MANTON ROAD WOOD. ENTREPRISE PARK. WORKSOP NOTTINGHAMDHIRE city: WORKSOP postcode: S80 2RS website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (WORKSOP)	participant	793˙750.00
4	KATHOLIEKE UNIVERSITEIT LEUVEN KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: OUDE MARKT 13 city: LEUVEN postcode: 3000 website: www.kuleuven.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	participant	517˙400.00
5	ACCELOPMENT AG ACCELOPMENT AG Organization address address: SEEFELDSTRASSE 198 city: ZUERICH postcode: 8008 website: www.accelopment.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	421˙171.00
6	CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER Organization address address: CALLE ROSSELLO 149 PUERTA BJS city: BARCELONA postcode: 8036 website: http://www.idibaps.org/en_index.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	360˙812.00
7	CENTRE EUROPEEN DE RECHERCHE CARDIOVASCULAIRE CERC CENTRE EUROPEEN DE RECHERCHE CARDIOVASCULAIRE CERC Organization address address: 7 RUE DU THEATRE city: MASSY postcode: 91300 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (MASSY)	participant	320˙000.00
8	UNIVERSITETSSYKEHUSET NORD-NORGE HF UNIVERSITETSSYKEHUSET NORD-NORGE HF Organization address address: SYKEHUSVEIEN 38 city: TROMSO postcode: 9019 website: www.unn.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (TROMSO)	participant	289˙253.00
9	UNIVERSITY OF EAST ANGLIA UNIVERSITY OF EAST ANGLIA Organization address address: EARLHAM ROAD city: NORWICH postcode: NR4 7TJ website: http://www.uea.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (NORWICH)	participant	267˙717.00
10	DEUTSCHES HERZZENTRUM MUNCHEN DEUTSCHES HERZZENTRUM MUNCHEN Organization address address: Lazarettstrasse 36 city: MUNICH postcode: 80636 website: www.dhm.mhn.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNICH)	participant	252˙500.00
11	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 website: www.uni-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	252˙500.00
12	UNIVERSITAIR ZIEKENHUIS ANTWERPEN UNIVERSITAIR ZIEKENHUIS ANTWERPEN Organization address address: WILRIJKSTRAAT 10 city: EDEGEM postcode: 2650 website: www.uza.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (EDEGEM)	participant	252˙500.00
13	AZIENDA OSPEDALIERA PAPA GIOVANNI XXIII AZIENDA OSPEDALIERA PAPA GIOVANNI XXIII Organization address address: PIAZZA OMS 1 city: BERGAMO postcode: 24127 website: www.ospedaliriuniti.bergamo.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (BERGAMO)	participant	252˙375.00
14	UNIVERSITAT POLITECNICA DE CATALUNYA UNIVERSITAT POLITECNICA DE CATALUNYA Organization address address: CALLE JORDI GIRONA 31 city: BARCELONA postcode: 8034 website: www.upc.edu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	148˙440.00
15	PAULA STRADINA KLINISKA UNIVERSITATES SLIMNICA PAULA STRADINA KLINISKA UNIVERSITATES SLIMNICA Organization address address: PILSONU IELA 13 city: RIGA postcode: 1002 website: www.stradini.lv contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LV (RIGA)	participant	82˙500.00
16	UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET Organization address address: HANSINE HANSENS VEG 14 city: TROMSO postcode: 9019 website: http://uit.no/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (TROMSO)	participant	14˙496.00

Map

Project objective

Heart attacks are common and can leave survivors suffering cardiogenic shock (CGS), with its extremely high risk of early death (42% versus 4% for non-CGS) and high incidence of chronic heart failure, with its associated socio-economic disease burden (ill-health, recurrent heart failure admissions, no return to full time activities, need for expensive therapeutic devices and life-long drugs). Outcomes from CGS are even worse in, females, the elderly (mortality>70%) and high risk sub-groups. The incidence of CGS in Europe alone is >50 000 patients pa. This unacceptably high mortality/morbidity rate represents a true unmet clinical need. No clear strategy exists to improve outcomes, with ad hoc therapies given too late in a spiralling, irrecoverable process. EURO SHOCK aims to improve outcomes for CGS patients. At its core is a robust phase3 randomised trial comparing a novel strategy of very early use of ECMO (Extracorporeal Membrane Oxygenation) to current standard of care. Evidence suggests very early ECMO will halt the spiral of decline and so significantly reduce 12 month death rate and need for heart failure re-admissions. Since both costs of CGS, and ECMO are high a health-economic cost efficacy analysis will be core. A cardiac magnetic resonance imaging sub-study will test novel protocols in sick patients and provide mechanistic data. We will test transfer networks for CGS patients and analyse ECG data to determine which patients benefit most from early transfer. Our multidisciplinary consortium comprises renowned physician-scientists, statisticians, health economists and technology providers, including specialised ECMO SME. EURO SHOCK will impact on heart attack survivors, healthcare providers and Europe`s medical technology sector by 1) reducing healthcare costs associated with CGS 2) provide novel cost effective framework for cardiac interventions 3) delivering innovative healthcare technologies and 4) informing guidelines for effective CGS intervention.

Deliverables

List of deliverables.
Dissemination and Outreach Plan (DOP)	Documents, reports	2019-10-15 13:15:19
Statistical analysis plan	Documents, reports	2019-10-15 13:15:26
EURO SHOCK website	Websites, patent fillings, videos etc.	2019-10-15 13:15:18
Training materials for sites in all relevant health economic aspects	Other	2019-10-15 13:15:27
Trial governance report	Documents, reports	2019-10-15 13:15:21

Take a look to the deliverables list in detail: detailed list of EURO SHOCK deliverables.

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