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ANCHOR
Articular cartilage regeneration through the recruitment of bone marrow derived mesenchymal stem cells into extracelluar matrix derived scaffolds anchored by 3D printed polymeric supports
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0ANCHOR project word cloud
Explore the words cloud of the ANCHOR project. It provides you a very rough idea of what is the project "ANCHOR" about.
leverage
articular
commercialise
prior
procedure
treat
economic
commercialization
ip
cartilage
orthopaedic
marrow
scaffolds
population
maximise
ecm
serious
arthritis
defect
defects
disease
patient
anchored
technically
supporting
synovial
bone
extensive
supports
inductivity
thereby
dramatically
chondro
printing
printed
10
repair
reducing
onset
faceted
create
consuming
inherent
subchondral
implantation
nearly
surgeons
cells
extracellular
matrix
3d
strategies
applicants
overcome
endogenous
transform
prohibitively
worldwide
hyaline
recruits
oa
health
time
obviate
scaffold
seeding
lines
joints
osteoarthritis
surgical
regeneration
anchor
polymeric
commercial
suturing
bones
stem
complexity
medicinal
recruiting
ineffective
biomaterials
damaged
expensive
form
Project "ANCHOR" data sheet
The following table provides information about the project.
| Coordinator |
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Organization address contact info |
| Coordinator Country | Ireland [IE] |
| Total cost | 149˙945 € |
| EC max contribution | 149˙945 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2017-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2018 |
| Duration (year-month-day) | from 2018-01-01 to 2019-06-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN | IE (DUBLIN) | coordinator | 124˙945.00 |
| 2 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN | IE (DUBLIN) | participant | 25˙000.00 |
Map
Project objective
Osteoarthritis (OA), the most common form of arthritis, is a serious disease of the joints affecting nearly 10% of the population worldwide. The onset of OA has been associated with defects to articular cartilage that lines the bones of synovial joints. Current strategies to treat articular cartilage defects are ineffective and/or prohibitively expensive. The aim of ANCHOR is to develop and commercialise a new medicinal product for articular cartilage regeneration that recruits endogenous bone marrow derived stem cells into an extracellular matrix derived scaffold anchored to the subchondral bone by 3D printed polymeric supports. By recruiting endogenous cells into a supporting scaffold, ANCHOR will obviate the need for pre-seeding scaffolds with cells prior to implantation into cartilage defects, thereby dramatically reducing the cost and complexity of the repair procedure. It will also overcome the need for suturing of a scaffold into a cartilage defect, which is a very time consuming and technically challenging surgical procedure. Finally, the inherent chondro-inductivity of the cartilage ECM derived scaffolds developed by the applicant will maximise the potential for hyaline cartilage regeneration. The project will leverage the applicants extensive experience in ECM derived biomaterials and 3D printing to develop a new product with significant commercial potential. The impact of ANCHOR will be multi-faceted: it will transform how damaged joints are treated by orthopaedic surgeons, it will create economic value through the commercialization of IP, and most importantly it will improve patient experience and their long-term health and well-being.
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The information about "ANCHOR" are provided by the European Opendata Portal: CORDIS opendata.
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lastchecktime (2024-07-16 12:28:27) correctly updated