Opendata, web and dolomites

INTACT SIGNED

Imaging NM: A Nanoparticulate Precision Medicine Approach to Target Cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 INTACT project word cloud

Explore the words cloud of the INTACT project. It provides you a very rough idea of what is the project "INTACT" about.

assures    alopecia    market    bladder    lab    neutropenia    death    avoids    personalisation    worldwide    patients    turns    efficacy    docetaxel    visualize    diseases    pet    cripec    patient    limited    intact    2022    exhibit    medicine    reg    drugs    projected    licensing    close    nanomedicines    deal    cancer    adverse    treat    oncologists    insufficient    ct    100m    launch    gap    significantly    whereby    decorated    receive    nanoparticles    enhanced    generation    revenues    heterogeneity    platform    trial    pharmacokinetic    cristal    business    exposing    therapeutic    treatment    perform    time    nanomedicine    10fte    biodistribution    ovarian    tumour    tracer    therapeutics    finalizing    site    generate    boost    appropriate    deals    2024    truly    selectively    validate    drug    superior    exceeding    develops    inappropriate    89zr    safety    profile    causes    preclinically    trials    gt    demonstrated    clinical    correlated    performance    personalized    options    maximum   

Project "INTACT" data sheet

The following table provides information about the project.

Coordinator
CRISTAL DELIVERY BV 

Organization address
address: OXFORDLAAN 55
city: MAASTRICHT
postcode: 6229 EV
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://www.cristaltherapeutics.com
 Total cost 8˙996˙610 €
 EC max contribution 2˙499˙999 € (28%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2017
 Duration (year-month-day) from 2017-08-01   to  2019-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CRISTAL DELIVERY BV NL (MAASTRICHT) coordinator 2˙499˙999.00

Map

 Project objective

Cristal Therapeutics (CT) develops the next generation of nanomedicines to treat cancer. Cancer remains one the leading causes of death worldwide, and current treatment options are insufficient, in part due to the tumour heterogeneity between patients. CT has developed state-of-the-art nanoparticles (CriPec®) to target a drug of choice more selectively to the tumour site(s). The superior therapeutic performance of this approach has already been demonstrated preclinically for CT’ lead product CriPec® docetaxel and a promising clinical phase I trial is finalizing, providing a significantly increased pharmacokinetic and safety profile. CT already observed activity in patients and much reduced neutropenia and alopecia. In INTACT, CT will perform phase II clinical trials in ovarian and bladder cancer to evaluate the therapeutic efficacy of CriPec® docetaxel. Furthermore, CriPec® docetaxel will be decorated with a PET tracer (89Zr), which enables oncologists to visualize CriPec® biodistribution in real-time. Tumour uptake will be correlated with therapeutic responses and result in parameters for future patient selection. This approach turns the drug into a personalized medicine whereby only those patients that exhibit enhanced tumour-targeting will be treated. This personalisation assures maximum efficacy in selected patients, avoids exposing patients to inappropriate drugs and adverse effects, and allows patients with limited tumour targeting to receive other more appropriate treatment. CT will use INTACT to close the gap from lab to market and facilitate a licensing deal for CriPec® docetaxel, projected to generate revenues exceeding >€100M in 2024. More importantly, INTACT will validate the CriPec® nanomedicine platform, boost product development for other diseases through licensing deals, and provide a growth of 10FTE by 2022. Success in INTACT will truly launch Cristal Therapeutics’ business.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "INTACT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "INTACT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.2.1.4.;H2020-EU.2.3.1.)

FlexiBiome (2018)

Next Generation Microbiome Platform

Read More  

N-IF (2017)

The N-IF mouse – a new and unique fibrosis model for preclinical efficacy studies

Read More  

SINUSLIGHT (2018)

Laser-spectroscopic sensing device for diagnostic assessment of sinusitis

Read More