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HepaCheC SIGNED

HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 HepaCheC project word cloud

Explore the words cloud of the HepaCheC project. It provides you a very rough idea of what is the project "HepaCheC" about.

monitor    methodology    requiring    ed    performed    surveillance    standardized    10    laboratory    detects    costly    international    patented    eminent    business    median    hepatitis    japan    fucosylated    discover    incorporated    accelerated    tumours    peptide    western    dependant    merely    diagnosis    grown    combination    diagnosed    glycoprotein    diagnostic    shallow    lifestyle    followed    company    world    glycobond    clinical    stage    elisa    patients    inadequate    carcinoma    validation    easily    minimally    polyclonal    biomarker    certain    antibody    hcc    decreasing    risk    relatively    plan    invasive    hepatocellular    competitiveness    mono    epidemic    solid    successful    agp    chances    standard    launch    workflow    commercial    cancer    specificity    obesity    survival    worldwide    place    acid    healthy    months    death    mainly    ultrasound    selectivity    detection    alpha    infections    blood    guidelines    vitro    size    house    correlates    liver    assay    hepachec    constitutes    elementary    protocols   

Project "HepaCheC" data sheet

The following table provides information about the project.

Coordinator
GLYCOBOND AB 

Organization address
address: TEKNIKRINGEN 1 F
city: LINKOPING
postcode: 583 30
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://glycobond.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-02-01   to  2018-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    GLYCOBOND AB SE (LINKOPING) coordinator 50˙000.00

Map

 Project objective

The objective of this project is to develop a business plan for the clinical validation and commercial launch of HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer (hepatocellular carcinoma (HCC)).

Current diagnostic methods (mainly ultrasound) are inadequate due to not being specific enough, being user-dependant, costly and only able to discover relatively shallow tumours that have grown to a certain size.

The HepaCheC assay, on the other hand, is a minimally invasive method (requiring a blood sample) with high selectivity and specificity that detects a specific liver cancer biomarker; fucosylated AGP (α1-acid glycoprotein). Glycobond’s patented Mono-F peptide constitutes the solid phase of the HepaCheC assay, followed by an in-house developed polyclonal AGP-specific antibody. The assay is based on the ELISA methodology, making it easily incorporated into the workflow of any standard diagnostic/research laboratory requiring only elementary laboratory know-how to be performed.

HCC is one of the leading cause of cancer death worldwide. Currently, only 10% of all HCC cases are diagnosed at an early stage, which directly correlates to decreasing chances of survival: the current median survival is merely 6-20 months following diagnosis. HCC is on the rise in the Western world due to a combination of an increase in Hepatitis B and C infections and our less healthy lifestyle that has resulted in an obesity epidemic. There is therefore an eminent need to improve standardized detection protocols.

The goal of Glycobond is to make HepaCheC part of the existing surveillance guidelines that are in place to monitor high-risk patients in the EU, US and Japan. If successful, the company will increase its international competitiveness and experience accelerated growth.

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The information about "HEPACHEC" are provided by the European Opendata Portal: CORDIS opendata.

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